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Characterization of the mechanism of action of Escherichia coli heat-stable enterotoxin

Data up to Jan 2025

Published1984
Citations47
References53

Total Citations Per Year

Abstract

References (53)

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1975 • 932 citations

Heat-stable enterotoxin of Escherichia coli: in vitro effects on guanylate cyclase activity, cyclic GMP concentration, and ion transport in small intestine.

1978 • 563 citations

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1979 • 553 citations

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1974 • 286 citations

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1980 • 284 citations

Biological evaluation of a methanol-soluble, heat-stable Escherichia coli enterotoxin in infant mice, pigs, rabbits, and calves

1978 • 272 citations

Activation of Intestinal Guanylate Cyclase by Heat-Stable Enterotoxin of Escherichia coli: Studies of Tissue Specificity, Potential Receptors, and Intermediates

1980 • 216 citations

Cyclic adenosine 3′,5′-monophosphate and prostacyclin inhibit membrane phospholipase activity in platelets

1977 • 204 citations

Mechanism for selectively inhibiting the activation of cyclic nucleotide phosphodiesterase and adenylate cyclase by antipsychotic agents.

1978 • 204 citations

Properties and regulation of guanylate cyclase and some proposed functions for cyclic GMP.

1979 • 187 citations

Purification and Chemical Characterization of the Heat-Stable Enterotoxin Produced by Porcine Strains of Enterotoxigenic Escherichia coli

1978 • 148 citations

The effect of 5,8,11,14‐eicosatetraynoic acid on lipid metabolism

1979 • 134 citations

A radioimmunoassay for thromboxane B2

1977 • 134 citations

Calmodulin: an overview.

1982 • 133 citations

Reversible inactivation of guanylate cyclase by mixed disulfide formation.

1981 • 132 citations

Adenosine Diphosphate-Ribosylation of Adenylate Cyclase Catalyzed by Heat-Labile Enterotoxin of Escherichia coli: Comparison with Cholera Toxin

1980 • 128 citations

Mode of action of heat-stable Escherichia coli enterotoxin Tissue and subcellular specificities and role of cyclic GMP

1980 • 119 citations

Arachidonate metabolism via lipoxygenase and 12L-hydroperoxy-5,8,10,14-icosatetraenoic acid peroxidase sensitive to anti-inflammatory drugs.

1980 • 118 citations

Effect of Purified Escherichia coli Heat-Stable Enterotoxin on Intestinal Cyclic Nucleotide Metabolism and Fluid Secretion

1979 • 102 citations

In Vitro Antisecretory Effects of Trifluoperazine and Other Neuroleptics in Rabbit and Human Small Intestine

1980 • 87 citations

Chemical properties of heat-stable enterotoxins produced by enterotoxigenic Escherichia coli of different host origins

1983 • 81 citations

Binding of Escherichia coli heat-stable enterotoxin to rat intestinal cells and brush border membranes

1984 • 76 citations

Escherichia coli heat-labile enterotoxin. Ganglioside specificity and ADP-ribosyltransferase activity.

1981 • 69 citations

Effects of phorbol ester tumor promoters on arachidonic acid metabolism in chick embryo fibroblasts.

1979 • 64 citations

Antisecretory effects of indomethacin on rabbit ileal mucosa in vitro

1981 • 53 citations

The Effect of Calcium and Prostaglandin Inhibitors on the Intestinal Fluid Response to Heat-Stable Enterotoxin of Escherichia coli

1982 • 46 citations

Comparison of Different Assays for Definition of Heat-Stable Enterotoxigenicity of Escherichia coli Porcine Strains

1980 • 46 citations

Inhibition of the secretory activity of Escherichia coli heat-stable enterotoxin by indomethacin

1978 • 45 citations

Hapten mimic elicits antibodies recognizing prostaglandin E2.

1978 • 42 citations

Inhibition of Escherichia coli heat-stable enterotoxin by indomethacin and chlorpromazine

1980 • 38 citations

Effect of chlorpromazine on the secretory activity of Escherichia coli heat-stable enterotoxin

1979 • 36 citations

Effect of extracellular calcium depletion on epithelial structure and function in rabbit ileum: a model for selective crypt or villus epithelial cell damage and suggestion of secretion by villus epithelial cells.

1982 • 34 citations

A rapid, solid phase radioimmunoassay for prostaglandin F2α and its main circulating metabolite

1976 • 31 citations

Cytolytic Mechanisms: Self-Destruction of Mammalian Cells by Activation of Endogenous Hydrolytic Enzymes

1982 • 29 citations

Lanthanum chloride inhibition of the secretory response to Escherichia coli heat-stable enterotoxin

1982 • 26 citations

Phorbol ester induced prostaglandin synthesis and [3H]-TPA metabolism by TPA-sensitive and TPA-resistant friend erythroleukemia cells

1979 • 26 citations

Reduction of the secretory response to Escherichia coli heat-stable enterotoxin by thiol and disulfide compounds

1983 • 25 citations

Effect of Heat-Stable Enterotoxin of Escherichia coli on Cultured Mammalian Cells

1983 • 23 citations

Effects of epinephrine, clonidine, <scp>L</scp>-phenylephrine, and morphine on intestinal secretion mediated by Escherichia coli heat-stable enterotoxin in pig jejunum

1982 • 23 citations

Effect of chlorpromazine on intestinal secretion mediated by Escherichia coli heat-stable enterotoxin and 8-Br-cyclic GMP in infant mice

1981 • 18 citations

Effect of chemical and pharmacological agents on the secretory activity induced by Escherichia coli heat-stable enterotoxin

1981 • 17 citations

Stimulation of calcium uptake and cyclic GMP synthesis in rat basophilic leukemia cells by Escherichia coli heat-stable enterotoxin

1983 • 16 citations

Cytosolic activator of adenylate cyclase: Reconstitution, characterization, and mechanism of action.

1983 • 16 citations

Inhibition of Escherichia coli heat-stable enterotoxin effects on intestinal guanylate cyclase and fluid secretion by quinacrine

1982 • 15 citations

Effects of indomethacin, acetazolamide, ethacrynate sodium, and atropine on intestinal secretion mediated by Escherichia coli heat-stable enterotoxin in pig jejunum

1982 • 14 citations

Effects of isolated heat-stable enterotoxin produced by Escherichia coli on fluid secretion and cyclic nucleotide levels in the jejunum of the weanling pig

1980 • 13 citations

Inhibition by non-steroidal anti-inflammatory agents of the ascorbate-induced elevations of platelet cyclic AMP levels.

1979 • 8 citations

Chemistry and Biology of the Heat-Stable Escherichia coli Enterotoxin

2015 • 6 citations

Failure of chlorpromazine to inhibit fluid accumulation caused by Escherichia coli heat-stable enterotoxin in suckling mice

1981 • 4 citations

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Characterization of the mechanism of action of Escherichia coli heat-stable enterotoxin (1984) – Infection and Immunity | Metascience Observatory Explorer