Escherichia coli heat-labile enterotoxin. Ganglioside specificity and ADP-ribosyltransferase activity.

PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENT

1951 • 319,299 citations

Mechanism of cholera toxin action: Covalent modification of the guanyl nucleotide-binding protein of the adenylate cyclase system

1978 • 902 citations

ADP-ribosylation of membrane proteins catalyzed by cholera toxin: basis of the activation of adenylate cyclase.

1978 • 732 citations

Interaction of Vibrio cholerae enterotoxin with cell membranes

1973 • 531 citations

HUMAN DIARRHEAL DISEASE CAUSED BY ENTEROTOXIGENIC ESCHERICHIA COLI

1975 • 440 citations

Travelers' Diarrhea in Mexico

1976 • 395 citations

Activation of Adenylate Cyclase by Choleragen

1979 • 394 citations

Mechanism of action of choleragen. Evidence for ADP-ribosyltransferase activity with arginine as an acceptor.

1977 • 391 citations

Travelers' Diarrhea and ToxigenicEscherichia coli

1975 • 322 citations

Genetic evidence that cholera toxin substrates are regulatory components of adenylate cyclase.

1978 • 281 citations

Comparison of the Tissue Receptors for Vibrio cholerae and Escherichia coli Enterotoxins by Means of Gangliosides and Natural Cholera Toxoid

1973 • 261 citations

Stimulation of Adenyl Cyclase by Escherichia coli Enterotoxin

1972 • 234 citations

Enzymic activity of cholera toxin. II. Relationships to proteolytic processing, disulfide bond reduction, and subunit composition.

1979 • 230 citations

Role of Toxigenic and Invasive Bacteria in Acute Diarrhea of Childhood

1975 • 229 citations

Hydrolysis of nicotinamide adenine dinucleotide by choleragen and its A protomer: possible role in the activation of adenylate cyclase.

1976 • 212 citations

Involvement of nicotinamide adenine dinucleotide in the action of cholera toxin in vitro.

1975 • 171 citations

Activation of Adenylate Cyclase by Heat-Labile Escherichia Coli Enterotoxin

1978 • 163 citations

Properties of homogeneous heat-labile enterotoxin from Escherichia coli

1980 • 151 citations

Dissociation and Recombination of the Subunits of the Cholera Enterotoxin (Choleragen)

1974 • 150 citations

Interaction of choleragen with the oligosaccharide of ganglioside GM1: evidence for multiple oligosaccharide Binding sites

1978 • 145 citations

DIFFERENTIAL INHIBITORY EFFECTS OF CHOLERA TOXOIDS AND GANGLIOSIDE ON THE ENTEROTOXINS OF VIBRIO CHOLERAE AND ESCHERICHIA COLI

1973 • 144 citations

Carbohydrate Components of Extraneuronal Gangliosides from Bovine and Human Spleen, and Bovine Kidney

1970 • 138 citations

Adenosine Diphosphate-Ribosylation of Adenylate Cyclase Catalyzed by Heat-Labile Enterotoxin of Escherichia coli: Comparison with Cholera Toxin

1980 • 128 citations

Cholera toxin interactions with thyrotropin receptors on thyroid plasma membranes.

1976 • 115 citations

Purification and Chemical Characterization of the Heat-Labile Enterotoxin Produced by Enterotoxigenic Escherichia coli

1979 • 106 citations

Effects of Cholera andE. coliEnterotoxins on Cyclic Adenosine 3'5'–Monophosphate Levels and Intermediary Metabolism in the Thyroid1

1973 • 106 citations

CHOLERA TOXIN

1977 • 98 citations

Biosynthesis of bovine thyroid gangliosides

1978 • 88 citations

Laboratory investigation of diarrhea in travelers to Mexico: evaluation of methods for detecting enterotoxigenic Echerichia coli

1976 • 82 citations

Mechanism of action of cholera toxin: Studies on the lag period

1980 • 82 citations

Stimulation of Intestinal Adenyl Cyclase by Escherichia coli Enterotoxin: Comparison of Strains from an Infant and an Adult with Diarrhea

1974 • 78 citations

Mechanisms of action of cholera and Escherichia coli enterotoxins

1979 • 76 citations

NAD-dependent ADP-ribosylation of arginine and proteins by Escherichia coli heat-labile enterotoxin.

1979 • 73 citations

Mechanism of action of cholera toxin: Effect of receptor density and multivalent binding on activation of adenylate cyclase

1980 • 72 citations

Absence of a Specific Ganglioside Galactosyltransferase in Mouse Cells Transformed by Murine Sarcoma Virus

1974 • 71 citations

Mechanism of Activation of Adenylate Cyclase in Vitro by Polymyxin-Released, Heat-Labile Enterotoxin of Escherichia coli

1976 • 71 citations

Inhibition of the steroidogenic effects of cholera and heat-labile Escherichia coli enterotoxins by GM1 ganglioside: evidence for a similar receptor site for the two toxins

1975 • 71 citations

Effect of gangliosides and substrate analogues on the hydrolysis of nicotinamide adenine dinucleotide by choleragen.

1977 • 71 citations

Toxins of Vibrio cholerae and Escherichia coli stimulate adenyl cyclase in rat fat cells

1974 • 61 citations

NAD glycohydrolase and ADP-ribosyltransferase activities are intrinsic to the A1 peptide of choleragen.

1979 • 57 citations

Comparison of the Action of Escherichia coli Enterotoxin on the Thymocyte Adenylate Cyclase-Cyclic Adenosine Monophosphate System to That of Cholera Toxin and Prostaglandin E 1

1974 • 56 citations

Gangliosides sensitize unresponsive fibroblasts to Escherichia coli heat-labile enterotoxin.

1979 • 51 citations

Interactions of Choleragenoid and GM1 Ganglioside with Enterotoxins of Vibrio cholerae and Escherichia coli in Cultured Adrenal Cells

1976 • 38 citations

Stimulation of intestinal and liver adenyl cyclase by enterotoxin from strains of Escherichia coli enteropathogenic for calves

1974 • 22 citations

Effects of choleragenoid and glucose on the response of dog intestine to Escherichia coli enterotoxins

1978 • 18 citations