Decreased synthesis and vasodilation to nitric oxide in piglets with hypoxia-induced pulmonary hypertension

A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding

1976 • 225,752 citations

A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

1976 • 200,127 citations

Vascular endothelial cells synthesize nitric oxide from L-arginine

1988 • 4,800 citations

Nitric oxide mediates glutamate-linked enhancement of cGMP levels in the cerebellum.

1989 • 1,850 citations

Purification and characterization of particulate endothelium-derived relaxing factor synthase from cultured and native bovine aortic endothelial cells.

1991 • 982 citations

Molecular mechanisms and therapeutic strategies related to nitric oxide

1995 • 791 citations

Calmodulin-dependent endothelium-derived relaxing factor/nitric oxide synthase activity is present in the particulate and cytosolic fractions of bovine aortic endothelial cells.

1991 • 599 citations

Role of endothelium-derived relaxing factor during transition of pulmonary circulation at birth

1990 • 447 citations

Hypoxia inhibits expression of eNOS via transcriptional and posttranscriptional mechanisms

1994 • 366 citations

Fetal and Neonatal Pulmonary Circulation

1979 • 336 citations

Techniques in diagnostic human biochemical genetics : a laboratory manual

1991 • 264 citations

Chronic hypoxia upregulates endothelial and inducible NO synthase gene and protein expression in rat lung

1996 • 261 citations

Prolonged in vivo hypoxia enhances nitric oxide synthase type I and type III gene expression in adult rat lung.

1995 • 207 citations

Pulmonary endothelial NO synthase gene expression is decreased in fetal lambs with pulmonary hypertension

1997 • 157 citations

Upregulation of Nitric Oxide Synthase Correlates Temporally With Onset of Pulmonary Vascular Remodeling in the Hypoxic Rat

1996 • 131 citations

Maturational changes in endothelium-derived relaxing factor activity of ovine pulmonary arteries in vitro

1991 • 125 citations

Nitric Oxide and cGMP Signaling

1995 • 124 citations

Chronic intrauterine pulmonary hypertension impairs endothelial nitric oxide synthase in the ovine fetus

1997 • 119 citations

Chronic hypoxia decreases nitric oxide production and endothelial nitric oxide synthase in newborn pig lungs

1998 • 117 citations

Pulmonary endothelial nitric oxide production is developmentally regulated in the fetus and newborn

1993 • 113 citations

Developmental changes in endothelium‐dependent pulmonary vasodilatation in pigs

1992 • 109 citations

Selective upregulation of arterial endothelial nitric oxide synthase in pulmonary hypertension

1997 • 108 citations

Disruption of cGMP production in pulmonary arteries isolated from fetal lambs with pulmonary hypertension

1995 • 104 citations

Peroxynitrite stimulates vascular smooth muscle cell cyclic GMP synthesis

1995 • 104 citations

Endothelial nitric oxide synthase is myristylated

1992 • 93 citations

Chronic hypoxia inhibits postnatal maturation of porcine intrapulmonary artery relaxation

1997 • 86 citations

Pulmonary endothelial nitric oxide synthase gene expression is decreased in a rat model of congenital diaphragmatic hernia.

1995 • 86 citations

An important role for endogenous synthesis of arginine in maintaining arginine homeostasis in neonatal pigs

1996 • 86 citations

L-arginine restores endothelium-dependent relaxation in pulmonary circulation of chronically hypoxic rats

1992 • 82 citations

High-Performance Liquid Chromatographic Determination of Nitric Oxide Synthase-Related Arginine Derivativesin Vitroandin Vivo

1997 • 72 citations

EDRF inhibition attenuates the increase in pulmonary blood flow due to oxygen ventilation in fetal lambs

1992 • 68 citations

Maturational changes in endothelium-derived relaxations in newborn piglet pulmonary circulation

1993 • 53 citations

Chronic hypoxia alters nitric oxide-dependent pulmonary vascular responses in lungs of newborn pigs

1996 • 52 citations

Progressive loss of vasodilator responsive component of pulmonary hypertension in neonatal calves exposed to 4,570 m

1993 • 44 citations

Effects of Excess Arginine with and without Supplemental Lysine on Performance, Plasma Amino Acid Concentrations and Nitrogen Balance of Young Swine

1984 • 33 citations

Endothelin receptor changes in hypoxia-induced pulmonary hypertension in the newborn piglet

1997 • 22 citations

Induction of nitric oxide synthase activity in pulmonary arteries from normoxic and chronically hypoxic rats

1997 • 20 citations

Reduced vasodilator response to ANF in hypoxia-induced pulmonary hypertension in the newborn piglet

1997 • 7 citations