Biliary atresia--translational research on key molecular processes regulating biliary injury and obstruction.

Alagille syndrome is caused by mutations in human Jagged1, which encodes a ligand for Notch1

1997 • 1,239 citations

Mutations in the human Jagged1 gene are responsible for Alagille syndrome

1997 • 1,121 citations

Congenital diseases of intrahepatic bile ducts: Variations on the theme “ductal plate malformation”

1992 • 564 citations

Reversal of Left-Right Asymmetry: a Situs Inversus Mutation

1993 • 470 citations

Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects

2000 • 337 citations

Biliary atresia: Current concepts and research directions. Summary of a symposium

1996 • 318 citations

Pathogenesis and Outcome of Biliary Atresia: Current Concepts

2003 • 293 citations

Detection of Group C Rotavirus in Infants with Extrahepatic Biliary Atresia

1996 • 242 citations

Studies of the aetiology of neonatal hepatitis and biliary atresia.

1977 • 238 citations

Detection of reovirus RNA in hepatobiliary tissues from patients with extrahepatic biliary atresia and choledochal cysts

1998 • 229 citations

Biliary Atresia and Reovirus Type 3 Infection

1982 • 228 citations

Group A Rotaviruses Produce Extrahepatic Biliary Obstruction in Orally Inoculated Newborn Mice

1993 • 221 citations

Genetic induction of proinflammatory immunity in children with biliary atresia

2002 • 203 citations

Immunohistochemistry of the liver and biliary tree in extrahepatic biliary atresia

2001 • 192 citations

Biliary Atresia Is Associated with CD4+ Th1 Cell–Mediated Portal Tract Inflammation

2004 • 191 citations

Obstruction of extrahepatic bile ducts by lymphocytes is regulated by IFN-γ in experimental biliary atresia

2004 • 186 citations

The Viral Association of Neonatal Cholestasis in Sweden: A Possible Link Between Cytomegalovirus Infection and Extrahepatic Biliary Atresia

1998 • 171 citations

Detection of retroviral antibodies in primary biliary cirrhosis and other idiopathic biliary disorders

1998 • 157 citations

New aspects in a murine model for extrahepatic biliary atresia

1997 • 136 citations

Extrahepatic biliary atresia: A disease or a phenotype?

2002 • 133 citations

Anomalous development of the hepatobiliary system in theinv mouse

1999 • 132 citations

The significance of human jagged 1 mutations detected in severe cases of extrahepatic biliary atresia

2002 • 116 citations

Extrahepatic biliary atresia and associated anomalies: Etiologic heterogeneity suggested by distinctive patterns of associations

1993 • 114 citations

COMPARATIVE STUDIES OF BILIARY ATRESIA IN THE HUMAN NEWBORN AND REOVIRUS‐INDUCED CHOLANGITIS IN WEANLING MICE

1982 • 113 citations

Lack of correlation between infection with reovirus 3 and extrahepatic biliary atresia or neonatal hepatitis

1988 • 112 citations

Congenital biliary atresia and jaundice in lambs and calves

1990 • 109 citations

Cytomegalovirus and Human Herpesvirus 6, but Not Human Papillomavirus, Are Present in Neonatal Giant Cell Hepatitis and Extrahepatic Biliary Atresia

2000 • 103 citations

Armed CD4+ Th1 effector cells and activated macrophages participate in bile duct injury in murine biliary atresia

2005 • 101 citations

Role of reovirus type 3 in persistent infantile cholestasis

1984 • 99 citations

Studies in the etiology of extrahepatic biliary atresia: Time-space clustering

1982 • 98 citations

Lack of Evidence for Rotavirus by Polymerase Chain Reaction/Enzyme Immunoassay of Hepatobiliary Samples from Children with Biliary Atresia

1997 • 98 citations

Elevation of serum interleukin-18 levels and activation of kupffer cells in biliary atresia

2000 • 94 citations

Hepatic overexpression of MHC Class II antigens and macrophage-associated antigens (CD68) in patients with biliary atresia of poor prognosis

1997 • 94 citations

Immunological Gap in the Infectious Animal Model for Biliary Atresia

2001 • 93 citations

Identification, genomic organization, chromosomal mapping and mutation analysis of the human INV gene, the ortholog of a murine gene implicated in left-right axis development and biliary atresia

2001 • 92 citations

Presence of Human Papillomavirus in Extrahepatic Biliary Atresia

1998 • 89 citations

Biliary Atresia and Cytomegalovirus Infection: A DNA Study

1999 • 88 citations

Detection of Reovirus Type 3 in the Porta Hepatis of an Infant with Extrahepatic Biliary Atresia: Ultrastructural and Immunocytochemical Study

1984 • 83 citations

The Pathogenesis of Biliary Atresia

1993 • 80 citations

Reovirus 3 not detected by reverse transcriptase—mediated polymerase chain reaction analysis of preserved tissue from infants with cholestatic liver disease

1995 • 79 citations

Increased expression of intercellular adhesion molecules in biliary atresia.

1994 • 77 citations

Biliary atresia, cytomegalovirus, and age at referral.

1996 • 76 citations

The inflammatory response in pediatric biliary disease: Macrophage phenotype and distribution

1996 • 73 citations

Different expression of HLA-DR and ICAM-1 in livers from patients with biliary atresia and Byler's disease

1997 • 73 citations

Degeneration of intrahepatic bile duct with lymphocyte infiltration into biliary epithelial cells in biliary atresia

1995 • 71 citations

The Role of Reovirus Type 3 Infection in an Established Murine Model for Biliary Atresia

2002 • 55 citations

Summary of a Symposium

1961 • 54 citations

Progress in Developing Animal Models for Biliary Atresia

1998 • 53 citations

CD8+ T cells infiltrating into bile ducts in biliary atresia do not appear to function as cytotoxic T cells: a clinicopathological analysis

2001 • 53 citations

Biliary atresia: Histopathologic observations and reflections upon its natural history

1977 • 53 citations

Association of the reovirus S1 gene with serotype 3-induced biliary atresia in mice

1994 • 50 citations

Reovirus serotype 3 infection in infants with extrahepatic biliary atresia or neonatal hepatitis

1994 • 43 citations

Differential Expression of the Major Histocompatibility Antigens and ICAM-1 on Bile Duct Epithelial Cells in Biliary Atresia.

1997 • 43 citations

Negative Serology for Hepatitis A and B Viruses in 18 Cases of Neonatal Cholestasis

1980 • 35 citations

Prenatal ultrasonographic appearance of type IIId (uncorrectable type with cystic dilatation) biliary atresia

2002 • 32 citations

EVALUATION OF THE ROLE OF HEPATITIS C VIRUS IN BILIARY ATRESIA

1994 • 30 citations

Immunologic Reaction and Genetic Factors in Biliary Atresia.

1997 • 27 citations

PEDIATRIC HEPATOLOGY

2000 • 26 citations

Rotavirus-induced murine biliary atresia is mediated by nuclear factor-κB

2005 • 25 citations

A histological study of extrahepatic biliary atresia.

1977 • 22 citations

The pathogenesis of biliary atresia in Japan: Immunohistochemical study of HBV‐associated antigen

1993 • 13 citations

Detection of human papillomavirus in juvenile laryngeal papillomatosis using polymerase chain reaction.

1995 • 13 citations