Diazoxide-induced insulin deficiency greatly reduced muscle protein synthesis in rats: involvement of eIF4E

The Neuroendocrinology of Stress and Aging: The Glucocorticoid Cascade Hypothesis*

1986 • 2,235 citations

The precision of ultraviolet absorption measurements in the Schmidt-Thannhauser procedure for nucleic acid estimation

1962 • 1,066 citations

A fluorometric method for the estimation of tyrosine in plasma and tissues.

1957 • 973 citations

Effects of insulin, glucose, and amino acids on protein turnover in rat diaphragm.

1975 • 916 citations

Initiation of Protein Synthesis in Eukaryotic Cells

1996 • 715 citations

Repression of cap-dependent translation by 4E-binding protein 1: competition with p220 for binding to eukaryotic initiation factor-4E.

1995 • 606 citations

Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?

1982 • 445 citations

Physiologic hyperinsulinemia stimulates protein synthesis and enhances transport of selected amino acids in human skeletal muscle.

1995 • 435 citations

Regulation by insulin of amino acid release and protein turnover in the perfused rat hemicorpus.

1977 • 294 citations

Chromatographic resolution of in vivo phosphorylated and nonphosphorylated eukaryotic translation initiation factor eIF-4E: increased cap affinity of the phosphorylated form.

1994 • 285 citations

Amino acid infusion increases the sensitivity of muscle protein synthesis in vivo to insulin. Effect of branched-chain amino acids

1988 • 279 citations

HORMONAL REGULATION OF HUMAN MUSCLE PROTEIN METABOLISM

1997 • 220 citations

Insulin stimulates protein synthesis in skeletal muscle by enhancing the association of eIF-4E and eIF-4G

1997 • 175 citations

Sensitivity and protein turnover response to glucocorticoids are different in skeletal muscle from adult and old rats. Lack of regulation of the ubiquitin-proteasome proteolytic pathway in aging.

1995 • 175 citations

Regulation of insulin-like growth factor-I and growth hormone receptor gene expression by diabetes and nutritional state in rat tissues

1989 • 175 citations

Euglycemic hyperinsulinemia augments amino acid uptake by human leg tissues during hyperaminoacidemia

1990 • 160 citations

IL-1 receptor antagonist attenuates sepsis-induced alterations in the IGF system and protein synthesis

1996 • 140 citations

Insulin and diabetes cause reciprocal changes in the association of eIF-4E and PHAS-I in rat skeletal muscle

1996 • 122 citations

The response of muscle protein synthesis to nutrient intake in postabsorptive rats: The role of insulin and amino acids

1986 • 120 citations

Nutrition and Somatomedin

1987 • 120 citations

Insulin-like growth factor-1 and insulin resistance in skeletal muscles of adult and old rats

1994 • 111 citations

Effects of diabetes on protein synthesis in fast- and slow-twitch rat skeletal muscle

1980 • 108 citations

Response of protein synthesis in human skeletal muscle to insulin: an investigation with L-[2H5]phenylalanine

1994 • 87 citations

Postprandial stimulation of muscle protein synthesis is independent of changes in insulin

1997 • 86 citations

Effects of starvation, diabetes and acute insulin treatment on the regulation of polypeptide-chain initiation in rat skeletal muscle

1984 • 86 citations

Changes in protein turnover in skeletal muscle in response to fasting.

1979 • 86 citations

The role of insulin, corticosterone and other factors in the acute recovery of muscle protein synthesis on refeeding food-deprived rats

1983 • 84 citations

Control of peptide-chain initiation in rat skeletal muscle. Development of methods for preparation of native ribosomal subunits and analysis of the effect of insulin on formation of 40 S initiation complexes.

1985 • 76 citations

Attenuated responses of muscle protein synthesis to fasting and insulin in adult female rats

1992 • 71 citations

Effect of denervation on the synthesis of ribonucleic acid and deoxyribonucleic acid in rat diaphragm muscle

1968 • 69 citations

Role of insulin and IGF-I in activation of muscle protein synthesis after oral feeding

1996 • 68 citations

Corticosterone modulates behavioral and metabolic effects of lipopolysaccharide

1996 • 67 citations

Effects of diabetes on protein turnover in cardiac muscle

1980 • 61 citations

Responses of protein synthesis in different skeletal muscles to fasting and insulin in rats

1991 • 58 citations

Insulin Stimulation of Protein Synthesis in Rat Skeletal Muscle Following Resistance Exercise Is Maintained With Advancing Age

1996 • 56 citations

The hormonal control of protein metabolism

1996 • 56 citations

Muscle protein synthesis in the streptozotocin-diabetic rat. A possible role for corticosterone in the insensitivity to insulin infusion in vivo

1982 • 53 citations

Effect of starvation on initiation of protein synthesis in skeletal muscle and heart.

1978 • 43 citations

Nutrition and Somatomedin. XIX. Molecular Regulation of Insulin-Like Growth Factor-1 in Streptozotocin-Diabetic Rats

1988 • 43 citations

Determination of plasma non-esterified fatty acids in herbivores and man : a comparison of values obtained by manual or automatic chromatographic, titrimetric, colorimetric and enzymatic methods

1984 • 42 citations

Acute effects of corticosterone on tissue protein synthesis and insulin-sensitivity in rats in vivo

1990 • 38 citations

The role of substrates in the regulation of protein metabolism

1996 • 34 citations

[Automated micro-determination of bovine plasma 3-hydroxybutyrate without deproteinization].

1986 • 17 citations

Regulation of initiation of protein synthesis by insulin in skeletal muscle

1991 • 17 citations

Effect of Dietary Protein Level on the First Steps of Glucagon Action in Rat Liver Plasma Membranes

1986 • 11 citations

Effects of corticotrophin-releasing factor and vasopressin on plasma adrenocorticotrophin molecular forms, aldosterone and corticosterone in young and adult rats and rabbits

1996 • 10 citations

Protein metabolism in diabetes mellitus

1995 • 5 citations