Interleukin-4 Downregulates Interleukin-6 Production in Human Peripheral Blood Mononuclear Cells

The biology of interleukin-6

1989 • 1,964 citations

Identification of a T cell-derived b cell growth factor distinct from interleukin 2.

1982 • 1,095 citations

Isolation and characterization of a mouse interleukin cDNA clone that expresses B-cell stimulatory factor 1 activities and T-cell- and mast-cell-stimulating activities.

1986 • 529 citations

IL-4 down-regulates IL-1 and TNF gene expression in human monocytes.

1989 • 421 citations

Modulation of phenotypic and functional properties of human peripheral blood monocytes by IL-4.

1988 • 303 citations

B cell stimulatory factor-1 (interleukin 4) activates macrophages for increased tumoricidal activity and expression of Ia antigens.

1987 • 299 citations

Receptors for B-cell stimulatory factor-1 expressed on cells of haematopoietic lineage

1987 • 280 citations

Regulation of interleukin-6 expression in cultured human blood monocytes and monocyte-derived macrophages

1988 • 234 citations

Characterization of the human B cell stimulatory factor 1 receptor.

1987 • 232 citations

Regulation of the expression of IL-6 in human monocytes.

1989 • 176 citations

IL-4 inhibits IL-2-mediated induction of human lymphokine-activated killer cells, but not the generation of antigen-specific cytotoxic T lymphocytes in mixed leukocyte cultures.

1988 • 167 citations

Regulation of cytolytic cell populations from human peripheral blood by B cell stimulatory factor 1 (interleukin 4).

1987 • 137 citations

The effects of IL-4 on human natural killer cells. A potent regulator of IL-2 activation and proliferation.

1988 • 118 citations

Interleukin 4 induces selective production of interleukin 6 from normal human B lymphocytes.

1989 • 93 citations

Influences of interleukins 2 and 4 on tumor necrosis factor production by murine mononuclear phagocytes.

1990 • 45 citations

TNF-α and IFN-γ reverse IL-4 inhibition of lymphokine-activated killer cell function

1990 • 20 citations

Interleukin 4 inhibits the interleukin 2-induced production of its functional antagonist, interferon gamma

1989 • 19 citations

Stimulation of Interleukin 6‐Like B‐Cell Differentiation Factor Production in Human Adherent Synovial Cells by Recombinant Interleukin 1

1989 • 11 citations