Challenge with high concentrations of cyclic AMP induces transient changes in the cytosolic free calcium concentration in Dictyostelium discoideum

Fine Structure Immunocytochemistry

1993 • 707 citations

A receptor for protons in the nerve cell membrane

1980 • 494 citations

The acrasin activity of adenosine-3',5'-cyclic phosphate.

1967 • 494 citations

Cryotechniques in biological electron microscopy

1988 • 406 citations

A STUDY OF EXTRACELLULAR SPACE IN CENTRAL NERVOUS TISSUE BY FREEZE-SUBSTITUTION

1965 • 404 citations

Adenosine 3′,5′-Monophosphate Waves in Dictyostelium discoideum : a Demonstration by Isotope Dilution—Fluorography

1981 • 393 citations

Intracellular oscillations and release of cyclic AMP from Dictyostelium cells

1975 • 305 citations

CYCLIC AMP AND OTHER SIGNALS CONTROLLING CELL DEVELOPMENT AND DIFFERENTIATION IN DICTYOSTELIUM

1987 • 240 citations

Regulation and function of Gα protein subunits in Dictyostelium

1989 • 227 citations

Cyclic GMP in Dictyostelium discoideum Oscillations and pulses in response to folic acid and cyclic AMP signals

1977 • 207 citations

G protein linked signal transduction pathways in development: Dictyostelium as an experimental system

1989 • 144 citations

Attractant-induced changes and oscillations of the extracellular Ca++ concentration in suspensions of differentiating Dictyostelium cells.

1984 • 143 citations

Cyclic-AMP stimulated calcium influx into aggregating cells of

1978 • 141 citations

Interaction of cAMP with the cell-surface receptor induces cell-type-specific mRNA accumulation in Dictyostelium discoideum.

1986 • 139 citations

CAR2, a prestalk cAMP receptor required for normal tip formation and late development of Dictyostelium discoideum.

1993 • 136 citations

Binding of cAMP derivatives to Dictyostelium discoideum cells. Activation mechanism of the cell surface cAMP receptor.

1983 • 135 citations

Quenched flow analysis of exocytosis in Paramecium cells: time course, changes in membrane structure, and calcium requirements revealed after rapid mixing and rapid freezing of intact cells.

1991 • 123 citations

A new class of rapidly developing mutants in Dictyostelium discoideum: Implications for cyclic AMP metabolism and cell differentiation

1983 • 121 citations

Inositol 1,4,5-trisphosphate induces calcium release from a non-mitochondrial pool in amoebae of Dictyostelium

1986 • 110 citations

Expression of a cAMP receptor gene of Dictyostelium and evidence for a multigene family.

1991 • 103 citations

Identification and targeted gene disruption of cAR3, a cAMP receptor subtype expressed during multicellular stages of Dictyostelium development.

1993 • 98 citations

The cyclic nucleotide specificity of three cAMP receptors in Dictyostelium.

1992 • 94 citations

cAMP induction of prespore and prestalk gene expression in Dictyostelium is mediated by the cell-surface cAMP receptor.

1986 • 86 citations

Isolation and characterization of cAMP unresponsive (frigid) aggregation‐deficient mutants of Dictyostelium discoideum

1982 • 71 citations

Cyclic AMP levels and turnover during development of the cellular slime mold Dictyostelium discoideum

1978 • 70 citations

The surface cyclic AMP receptors, cAR1, cAR2, and cAR3, promote Ca2+ influx in Dictyostelium discoideum by a G alpha 2-independent mechanism.

1993 • 64 citations

Intracellular calcium during chemotaxis of Dictyostelium discoideum: a new fura-2 derivative avoids sequestration of the indicator and allows long-term calcium measurements.

1992 • 62 citations

Cyclic AMP receptors and the control of cell aggregation in Dictyostelium.

1976 • 61 citations

Signal transduction pathways controlling multicellular development in Dictyostelium

1991 • 59 citations

Oscillations of Ca+ + concentration during the cell differentiation of Dictyostelium discoideum

1986 • 59 citations

Two transmembrane signaling mechanisms control expression of the cAMP receptor gene CAR1 during Dictyostelium development.

1993 • 58 citations

Gtp Analogues Stimulate Inositol Trisphosphate Formation Transiently In Dictyostelium

1987 • 49 citations

Specific photoaffinity labeling of the cAMP surface receptor in Dictyostelium discoideum.

1984 • 49 citations

Down-regulation of cell surface cyclic AMP receptors and desensitization of cyclic AMP-stimulated adenylate cyclase by cyclic AMP in Dictyostelium discoideum. Kinetics and concentration dependence.

1987 • 47 citations

On the role of calcium in chemotaxis and oscillations of dictyostelium cells

1982 • 42 citations

Ca+ + antagonists distinguish different requirements for cAMP-mediated gene expression in the cellular slime mold, Dictyostelium discoideum

1989 • 37 citations

The determination of spatial pattern inDictyostelium discoideum

1992 • 37 citations

Mutant analysis suggests that cyclic GMP mediates the cyclic AMP-induced Ca2+ uptake in Dictyostelium

1991 • 36 citations

Determination of the concentration of free Ca2+ in the presence of magnesium (or manganese) and chelating effectors of the NAD+-linked isocitrate dehydrogenase

1979 • 36 citations

Visualization and measurement of calcium transients in Amoeba proteus by fura-2 fluorescence.

1991 • 35 citations

Cyclic AMP- and Ins(1,4,5)P3-induced ca2+ fluxes in permeabilised cells of Dictyostelium discoideum: cGMP regulates ca2+ entry across the plasma membrane

1993 • 34 citations

Signal transduction pathways controlling multicellular development in Dictyostelium

1991 • 30 citations

A Ca²⁺‐dependent signal transduction system participates in coupling expression of some cAMP‐dependent prespore genes to the cell surface receptor

1988 • 22 citations

Potential morphogens involved in pattern formation during Dictyostelium differentiation

1991 • 20 citations

Differential effects of temperature on cAMP-induced excitation, adaptation, and deadaptation of adenylate and guanylate cyclase in Dictyostelium discoideum.

1987 • 20 citations

Polarized Structures of Cells in the Aggregating Cellular Slime Mold D. discoideum: An Electron Microscope Study

1977 • 14 citations