Nitric oxide exposure inhibits endothelial NOS activity but not gene expression: a role for superoxide

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase

1992 • 1,499 citations

Inhaled Nitric Oxide and Persistent Pulmonary Hypertension of the Newborn

1997 • 787 citations

Evidence for enhanced vascular superoxide anion production in nitrate tolerance. A novel mechanism underlying tolerance and cross-tolerance.

1995 • 660 citations

A novel citrulline-forming enzyme implicated in the formation of nitric oxide by vascular endothelial cells

1989 • 612 citations

NADH oxidoreductase is a major source of superoxide anion in bovine coronary artery endothelium

1994 • 546 citations

Feedback inhibition of nitric oxide synthase activity by nitric oxide

1993 • 396 citations

Translational regulation via iron-responsive elements by the nitric oxide/NO-synthase pathway.

1993 • 393 citations

Negative feedback regulation of endothelial cell function by nitric oxide.

1993 • 371 citations

Inhibition of Cytochromes P450 by Nitric Oxide and a Nitric Oxide-Releasing Agent

1993 • 358 citations

Nitric oxide is a mediator of the decrease in cytochrome P450-dependent metabolism caused by immunostimulants.

1993 • 287 citations

The primary localization of free radical generation after anoxia/reoxygenation in isolated endothelial cells.

1987 • 285 citations

Conformation, co-operativity and ligand binding in human hemoglobin

1975 • 263 citations

Agonist-Induced Peroxynitrite Production from Endothelial Cells

1994 • 254 citations

Constitutive nitric oxide synthase from cerebellum is reversibly inhibited by nitric oxide formed from L-arginine

1992 • 254 citations

Inducible nitric oxide synthase from a rat alveolar macrophage cell line is inhibited by nitric oxide.

1993 • 225 citations

Agonist-modulated Palmitoylation of Endothelial Nitric Oxide Synthase

1995 • 220 citations

Inhibition of coronary artery superoxide dismutase attenuates endothelium-dependent and -independent nitrovasodilator relaxation.

1991 • 215 citations

Oxidation and reduction of hemoproteins by trioxodinitrate(II). The role of nitrosyl hydride and nitrite

1988 • 212 citations

Nitric oxide inhibits neuronal nitric oxide synthase by interacting with the heme prosthetic group. Role of tetrahydrobiopterin in modulating the inhibitory action of nitric oxide.

1994 • 199 citations

Inhibition of cytochromes P4501A by nitric oxide.

1994 • 198 citations

Nitric oxide and cGMP analogs activate transcription from AP‐1‐responsive promoters in mammalian cells

1995 • 193 citations

Inhibition of Endothelial Nitric Oxide Synthase Activity by Protein Kinase C

1995 • 188 citations

Rebound Pulmonary Hypertension After Inhalation of Nitric Oxide

1996 • 184 citations

Nitric oxide synthase from cerebellum catalyzes the formation of equimolar quantities of nitric oxide and citrulline from L-arginine

1992 • 181 citations

Superoxide anion release by human endothelial cells: Synergism between a phorbol ester and a calcium ionophore

1986 • 165 citations

Mutation of N-myristoylation site converts endothelial cell nitric oxide synthase from a membrane to a cytosolic protein.

1993 • 162 citations

Bradykinin induces superoxide anion release from human endothelial cells

1990 • 142 citations

Superoxide Formation and Macrophage Resistance to Nitric Oxide-mediated Apoptosis

1997 • 121 citations

Spectral Characterization and Effect on Catalytic Activity of Nitric Oxide Complexes of Inducible Nitric Oxide Synthase

1995 • 119 citations

Intracellular generation of reactive oxygen species in endothelial cells exposed to anoxia-reoxygenation

1997 • 115 citations

Role of superoxide anion and endothelium in vasoconstrictor action of prostaglandin endoperoxide

1992 • 90 citations

Nitric oxide-induced inhibition of lung endothelial cell nitric oxide synthase via interaction with allosteric thiols: role of thioredoxin in regulation of catalytic activity.

1996 • 84 citations

NMDA and nitric oxide act through the cGMP signal transduction pathway to repress hypothalamic gonadotropin-releasing hormone gene expression.

1996 • 78 citations

Inhaled Nitric Oxide Selectively Decreases Pulmonary Vascular Resistance without Impairing Oxygenation during One-lung Ventilation in Patients Undergoing Cardiac Surgery

1994 • 74 citations

Inhaled Nitric Oxide Therapy

1995 • 73 citations

Pharmacology of endothelium-derived nitric oxide and nitrovasodilators.

1991 • 73 citations

[7] Methods for the study of superoxide chemistry in nonaqueous solutions

1984 • 67 citations

cAMP post-transcriptionally diminishes the abundance of adrenodoxin reductase mRNA.

1992 • 62 citations

Growth factor induction of nitric oxide synthase in rat pheochromocytoma cells

1997 • 56 citations

Regulation of proteins in the cholesterol side-chain cleavage system in JEG-3 and Y-1 cells.

1993 • 56 citations

Nitric oxide induces c-fos gene expression via cyclic AMP response element binding protein (CREB) phosphorylation in rat retinal pigment epithelium

1995 • 53 citations

Tumor necrosis factor-alpha decreases pulmonary artery endothelial nitrovasodilator via protein kinase C

1994 • 14 citations

Characterization of Rat Neuronal Nitric Oxide Synthase Expressed inSaccharomyces cerevisiae

1995 • 12 citations