Comprehensive molecular profiling of lung adenocarcinoma

EGFR Mutations in Lung Cancer: Correlation with Clinical Response to Gefitinib Therapy

2004 • 9,201 citations

Mutational heterogeneity in cancer and the search for new cancer-associated genes

2013 • 5,186 citations

Sensitive detection of somatic point mutations in impure and heterogeneous cancer samples

2013 • 4,522 citations

International Association for the Study of Lung Cancer/American Thoracic Society/European Respiratory Society International Multidisciplinary Classification of Lung Adenocarcinoma

2011 • 4,371 citations

Anaplastic Lymphoma Kinase Inhibition in Non–Small-Cell Lung Cancer

2010 • 4,281 citations

Comprehensive genomic characterization of squamous cell lung cancers

2012 • 3,654 citations

Discovery and saturation analysis of cancer genes across 21 tumour types

2014 • 2,855 citations

Somatic mutations affect key pathways in lung adenocarcinoma

2008 • 2,653 citations

Classification of human lung carcinomas by mRNA expression profiling reveals distinct adenocarcinoma subclasses

2001 • 2,560 citations

Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development

2011 • 2,254 citations

Gene-expression profiles predict survival of patients with lung adenocarcinoma

2002 • 2,005 citations

Absolute quantification of somatic DNA alterations in human cancer

2012 • 1,898 citations

Mapping the Hallmarks of Lung Adenocarcinoma with Massively Parallel Sequencing

2012 • 1,734 citations

ROS1 Rearrangements Define a Unique Molecular Class of Lung Cancers

2012 • 1,480 citations

Integrative genome analyses identify key somatic driver mutations of small-cell lung cancer

2012 • 1,296 citations

p53: A Frequent Target for Genetic Abnormalities in Lung Cancer

1989 • 1,214 citations

Characterizing the cancer genome in lung adenocarcinoma

2007 • 1,110 citations

Genomic Landscape of Non-Small Cell Lung Cancer in Smokers and Never-Smokers

2012 • 1,100 citations

Assessing the significance of chromosomal aberrations in cancer: Methodology and application to glioma

2007 • 1,049 citations

Comprehensive genomic analysis identifies SOX2 as a frequently amplified gene in small-cell lung cancer

2012 • 996 citations

Dysfunctional KEAP1–NRF2 Interaction in Non-Small-Cell Lung Cancer

2006 • 985 citations

Intragenic ERBB2 kinase mutations in tumours

2004 • 753 citations

The transcriptional landscape and mutational profile of lung adenocarcinoma

2012 • 554 citations

New Pathologic Classification of Lung Cancer: Relevance for Clinical Practice and Clinical Trials

2013 • 534 citations

The Relationship between Epidermal Growth Factor Receptor Mutations and Clinicopathologic Features in Non–Small Cell Lung Cancers

2005 • 492 citations

Somatic Mutations Lead to an Oncogenic Deletion of Met in Lung Cancer

2006 • 458 citations

Response to Cabozantinib in Patients with RET Fusion-Positive Lung Adenocarcinomas

2013 • 448 citations

Functional recognition of the 3′ splice site AG by the splicing factor U2AF35

1999 • 438 citations

Pattern discovery and cancer gene identification in integrated cancer genomic data

2013 • 409 citations

TTF-1 Expression in Pulmonary Adenocarcinomas

2002 • 372 citations

Gene Expression Profiling Reveals Reproducible Human Lung Adenocarcinoma Subtypes in Multiple Independent Patient Cohorts

2006 • 287 citations

Differential Pathogenesis of Lung Adenocarcinoma Subtypes Involving Sequence Mutations, Copy Number, Chromosomal Instability, and Methylation

2012 • 262 citations

Frequent BRG1/SMARCA4-inactivating mutations in human lung cancer cell lines

2008 • 251 citations

Proteomic and transcriptomic profiling reveals a link between the PI3K pathway and lower estrogen-receptor (ER) levels and activity in ER+ breast cancer

2010 • 245 citations

Mga, a dual-specificity transcription factor that interacts with Max and contains a T-domain DNA-binding motif

1999 • 174 citations

A Pan-Cancer Analysis of Transcriptome Changes Associated with Somatic Mutations in U2AF1 Reveals Commonly Altered Splicing Events

2014 • 170 citations

Oncogenic RIT1 mutations in lung adenocarcinoma

2014 • 80 citations

Integrated analysis of genetic and epigenetic alterations reveals CpG island methylator phenotype associated with distinct clinical characters of lung adenocarcinoma

2012 • 58 citations

A Novel Gene, DXS8237E, Lies within 20 kb Upstream of UBE1 in Xp11.23 and Has a Different X Inactivation Status

1996 • 31 citations