Gene rearrangements as markers of clonal variation and minimal residual disease in acute lymphoblastic leukemia.

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

The Clonal Evolution of Tumor Cell Populations

1976 • 6,310 citations

A human T cell-specific cDNA clone encodes a protein having extensive homology to immunoglobulin chains

1984 • 1,262 citations

Isolation of cDNA clones encoding T cell-specific membrane-associated proteins

1984 • 1,239 citations

Structure of the human immunoglobulin μ locus: Characterization of embryonic and rearranged J and D genes

1981 • 959 citations

Joining of immunoglobulin heavy chain gene segments: implications from a chromosome with evidence of three D-JH fusions.

1982 • 755 citations

Evolution of tumours and the impact of molecular oncology

1985 • 666 citations

Immunoglobulin-Gene Rearrangements as Unique Clonal Markers in Human Lymphoid Neoplasms

1983 • 621 citations

Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins.

1983 • 605 citations

Developmental hierarchy of immunoglobulin gene rearrangements in human leukemic pre-B-cells.

1981 • 576 citations

Pre-B-Cell Leukemia

1978 • 428 citations

Cloned human and mouse kappa immunoglobulin constant and J region genes conserve homology in functional segments

1980 • 402 citations

Clustered arrangement of immunoglobulin λ constant region genes in man

1981 • 379 citations

Rearrangements of Genes for the Antigen Receptor on T Cells as Markers of Lineage and Clonality in Human Lymphoid Neoplasms

1985 • 367 citations

B cell origin of non-T cell acute lymphoblastic leukemia. A model for discrete stages of neoplastic and normal pre-B cell differentiation.

1984 • 324 citations

Continuing kappa-gene rearrangement in a cell line transformed by Abelson murine leukemia virus

1982 • 278 citations

ACUTE LYMPHOBLASTIC LEUKÆMIA IN CHILDREN: CLASSIFICATION AND PROGNOSIS

1977 • 256 citations

Structure of human immunoglobulin gamma genes: implications for evolution of a gene family

1982 • 231 citations

Biclonal B-Cell Lymphoma

1984 • 212 citations

Immunological Classification of Acute Lymphoblastic Leukaemias: Evaluation of its Clinical Significance in a Hundred Patients

1976 • 210 citations

High capacity gel preparative electrophoresis for purification of fragments of genomic DNA

1978 • 128 citations

Acute lymphoblastic leukemia with pre-B-cell characteristics

1979 • 116 citations

Adult acute lymphoblastic leukemia phenotypes defined by monoclonal antibodies

1985 • 109 citations

Biologic and prognostic significance of the presence of more than two mu heavy-chain genes in childhood acute lymphoblastic leukemia of B precursor cell origin

1986 • 95 citations

Acute lymphoblastic leukaemia associated antigen. III Alterations in expression during treatment and in relapse

1980 • 87 citations

Immunoglobulin gene rearrangements in remission bone marrow specimens from patients with acute lymphoblastic leukemia

1986 • 81 citations

CLINICAL USEFULNESS OF MONOCLONAL- ANTIBODY PHENOTYPING IN CHILDHOOD ACUTE LYMPHOBLASTIC LEUKAEMIA

1982 • 76 citations

Shifts in expression of cell membrane phenotypes in childhood lymphoid malignancies at relapse

1979 • 54 citations

Predicting Relapse of Human Leukemia by Means of Premature Chromosome Condensation

1980 • 50 citations

Pre-B-cells in normal human bone marrow and in bone marrow from patients with leukemia in remission: persistent quantitative differences and possible expression of cell surface IgM in vitro

1983 • 17 citations

Chromosome Abnormalities in Adult Acute Leukemia: Biologic and Therapeutic Significance

1982 • 13 citations

Evaluation of leukemic cell chromosomes as a guide to therapy.

1982 • 11 citations

Evidence for clonal evolution in pre-B-cell leukaemia

1984 • 10 citations

Human malignancy-associated nucleolar antigen as a marker for tumor cells in patients with acute leukemia

1984 • 7 citations

Terminal-Deoxynucleotidyl Transferase (TdT): Serial Observations on Patients with Leukemia

1983 • 7 citations