Structure and Function of Kinetochores in Budding Yeast

Checkpoints: Controls That Ensure the Order of Cell Cycle Events

1989 • 3,036 citations

Feedback control of mitosis in budding yeast

1991 • 1,167 citations

Isolation of a yeast centromere and construction of functional small circular chromosomes

1980 • 788 citations

Creative blocks: cell-cycle checkpoints and feedback controls

1992 • 686 citations

Behavior of spindles and spindle plaques in the cell cycle and conjugation of Saccharomyces cerevisiae

1975 • 617 citations

Mitotic forces control a cell-cycle checkpoint

1995 • 535 citations

Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle.

1994 • 511 citations

Kinetochores are transported poleward along a single astral microtubule during chromosome attachment to the spindle in newt lung cells.

1990 • 488 citations

Mitotic stability of yeast chromosomes: A colony color assay that measures nondisjunction and chromosome loss

1985 • 486 citations

Construction of artificial chromosomes in yeast

1983 • 448 citations

Evidence that the MIF2 gene of Saccharomyces cerevisiae encodes a centromere protein with homology to the mammalian centromere protein CENP-C.

1995 • 410 citations

Two Saccharomyces cerevisiae kinesin-related gene products required for mitotic spindle assembly.

1992 • 401 citations

A mutation in CSE4, an essential gene encoding a novel chromatin-associated protein in yeast, causes chromosome nondisjunction and cell cycle arrest at mitosis.

1995 • 393 citations

Directional instability of kinetochore motility during chromosome congression and segregation in mitotic newt lung cells: a push-pull mechanism

1993 • 389 citations

Kinesin-related proteins required for assembly of the mitotic spindle.

1992 • 347 citations

CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate

1992 • 340 citations

Mitotic chromosome transmission fidelity mutants in Saccharomyces cerevisiae.

1990 • 333 citations

Genetic manipulation of centromere function.

1987 • 207 citations

Mutational analysis of centromere DNA from chromosome VI of Saccharomyces cerevisiae.

1988 • 148 citations

CSE1 and CSE2, two new genes required for accurate mitotic chromosome segregation in Saccharomyces cerevisiae.

1993 • 138 citations

Zinc-finger proteins

1993 • 136 citations

Isolation and characterization of a gene (CBF2) specifying a protein component of the budding yeast kinetochore.

1993 • 112 citations

Microtubule-motor activity of a yeast centromere-binding protein complex

1992 • 112 citations

Isolation of two genes that affect mitotic chromosome transmission in S. cerevisiae

1986 • 101 citations

Disruption of centromere assembly during interphase inhibits kinetochore morphogenesis and function in mitosis

1991 • 96 citations

Factors required for the binding of reassembled yeast kinetochores to microtubules in vitro.

1994 • 95 citations

Alterations in the adenine-plus-thymine-rich region of CEN3 affect centromere function in Saccharomyces cerevisiae.

1987 • 92 citations

The dynamics of chromosome movement in the budding yeast Saccharomyces cerevisiae.

1989 • 86 citations

Purification of a yeast centromere-binding protein that is able to distinguish single base-pair mutations in its recognition site.

1989 • 81 citations

Motor proteins in cell division

1991 • 67 citations

A new role for motor proteins as couplers to depolymerizing microtubules.

1995 • 67 citations

Identification and genetic mapping of CHL genes controlling mitotic chromosome transmission in yeast

1993 • 56 citations

In vivo analysis of the Saccharomyces cerevisiae centromere CDEIII sequence: requirements for mitotic chromosome segregation.

1991 • 47 citations

A chromosome breakage assay to monitor mitotic forces in budding yeast

1994 • 46 citations

In Vivo Characterization of the Saccharomyces cerevisiae Centromere DNA Element I, a Binding Site for the Helix-Loop-Helix Protein CPF1

1991 • 43 citations

Analysis of centromere function in Saccharomyces cerevisiae using synthetic centromere mutants

1991 • 34 citations

Point mutations that separate the role of Saccharomyces cerevisiae centromere binding factor 1 in chromosome segregation from its role in transcriptional activation.

1993 • 28 citations

Mutational analysis of centromeric DNA elements of Klayveromyces lactis and their role in determining the species specificity of the highly homologous centromeres from K. lactis and Saccharomyces cerevisiae

1994 • 28 citations

Saccharomyces cerevisiae mutants defective in chromosome segregation

1989 • 21 citations