Involvement of Acetaldehyde in Alcohol Addiction

Localization of brain reinforcement mechanisms: intracranial self-administration and intracranial place-conditioning studies

1999 • 573 citations

Intracranial self-administration of morphine into the ventral tegmental area in rats

1981 • 497 citations

Cortical Dopaminergic Involvement in Cocaine Reinforcement

1983 • 491 citations

Self-injection of amphetamine directly into the brain

1983 • 373 citations

Preferential Utilization of Acetate by Astrocytes Is Attributable to Transport

1998 • 362 citations

Ethanol self-infusion into the ventral tegmental area by alcohol-preferring rats

1994 • 270 citations

Self-administration of morphine, DAMGO, and DPDPE into the ventral tegmental area of rats

1994 • 253 citations

Regional heterogeneity for the intracranial self-administration of ethanol within the ventral tegmental area of female Wistar rats

2000 • 211 citations

Alcohol Drinking: Abnormal Intake Caused by Tetrahydropapaveroline in Brain

1977 • 183 citations

Ethanol metabolism in rat brain homogenates by a catalase-H2O2 system

1992 • 179 citations

Enzymatic Production of Acetaldehyde from Ethanol in Rat Brain Tissue

1992 • 175 citations

Role of acetaldehyde in the actions of ethanol on the brain — A review

1996 • 170 citations

Brain acetaldehyde after ethanol administration

1976 • 169 citations

Reinforcing properties of cocaine in the medial prefrontal cortex: Primary action on presynaptic dopaminergic terminals

1986 • 169 citations

Role of ethanol-inducible cytochrome P450 (P450IIE1) in catalysing the free radical activation of aliphatic alcohols

1991 • 146 citations

Catalase Mediates Acetaldehyde Formation from Ethanol in Fetal and Neonatal Rat Brain

1997 • 133 citations

Ethanol Oxidation by Rat Brain in Vivo

1980 • 132 citations

Intraventricular self-administration of acetaldehyde, but not ethanol, in naive laboratory rats

1979 • 127 citations

Ethanol metabolism in the brain

1997 • 127 citations

Central nervous system effects of acetate: contribution to the central effects of ethanol.

1991 • 123 citations

Distribution and Kinetics of Ethanol Metabolism in Rat Brain

1998 • 109 citations

Conditioned place preference induced by intraventricular infusions of acetaldehyde

1984 • 102 citations

The effect of 3-amino-1,2,4-triazole on voluntary ethanol consumption: Evidence for brain catalase involvement in the mechanism of action

1992 • 99 citations

Behavioral and Physiological Effects of Ethanol in High‐Risk and Control Children: A Pilot Study

1983 • 91 citations

A critical evaluation of tetrahydroisoquinoline induced ethanol preference in rats

1980 • 90 citations

Histochemical Study of Aldehyde Dehydrogenase in the Rat CNS

1991 • 86 citations

Catalase and the production of brain acetaldehyde: a possible mediator of the psychopharmacological effects of ethanol

1997 • 80 citations

Intraventricular self-administration of acetaldehyde and voluntary consumption of ethanol in rats

1980 • 75 citations

Increased Salsolinol Levels in Rat Striatum and Limbic Forebrain Following Chronic Ethanol Treatment

1982 • 67 citations

Electrolytic microinfusion transducer system: an alternative method of intracranial drug application

1980 • 62 citations

Regional H2O2 concentration in rat brain after hyperoxic convulsions

1990 • 59 citations

A correlation between voluntary ethanol consumption and brain catalase activity in the rat

1985 • 58 citations

Possible involvement of acetaldehyde, norepinephrine and their tetrahydroisoquinoline derivatives in the regulation of ethanol self-administration

1977 • 56 citations

Cocaine Is Self‐administered into the Shell Region of the Nucleus Accumbens in Wistar Rats

1999 • 54 citations

Characterization of the Production of Acetaldehyde by Astrocytes in Culture after Ethanol Exposure

1997 • 50 citations

Determination of (R)- and (S)-Salsolinol sulfate and dopamine sulfate levels in plasma of nonalcoholics and alcoholics

1995 • 50 citations

Plasma and Urine Salsolinol in Humans: Effect of Acute Ethanol Intake on the Enantiomeric Composition of Salsolinol

1996 • 49 citations

Intracranial self-administration methodologies

1987 • 45 citations

Alcohol‐Induced Euphoria Enhanced by Disulfiram and Calcium Carbimide

1983 • 39 citations

Alcohol induces formation of morphine precursors in the striatum of rats

1996 • 39 citations

Catalase activity measured in rats naive to ethanol correlates with later voluntary ethanol consumption: possible evidence for a biological marker system of ethanol intake

1988 • 37 citations

Enzymic Catalysis of the Accumulation of Acetaldehyde From Ethanol in Human Prenatal Cephalic Tissues: Evaluation of the Relative Contributions of CYP2E1, Alcohol Dehydrogenase, and Catalase/Peroxidases

2000 • 31 citations

Family History of Alcoholism and the Mediation of Alcohol Intake by Catalase: Further Evidence for Catalase as a Marker of the Propensity to Ingest Alcohol

1995 • 28 citations

RELATIONSHIP BETWEEN BLOOD CATALASE ACTIVITY AND DRINKING HISTORY IN A HUMAN POPULATION, A POSSIBLE BIOLOGICAL MARKER OF THE AFFINITY TO CONSUME ALCOHOL

1992 • 28 citations

Free Radical Production After Exposure of Astrocytes and Astrocytic C6 Glioma Cells to Ethanol. Preliminary Results

1997 • 25 citations

The quantitative determination of R‐ and S‐salsolinol in the striatum and adrenal gland of rats selectively bred for disparate alcohol drinking

1999 • 20 citations

Relationship of Brain Ethanol Metabolism to the Hypnotic Effect of Ethanol. I: Studies in Outbred Animals

2001 • 20 citations

Relationship of Brain Ethanol Metabolism to the Hypnotic Effect of Ethanol. II: Studies in Selectively Bred Rats and Mice

2001 • 20 citations

Catalase as a regulator of the propensity to ingest alcohol in genetically determined acatalasemic individuals from Israel

1999 • 8 citations