Focal infection: new age or ancient history?

Systemic Diseases Caused by Oral Infection

2000 • 1,009 citations

Infections as a major preventable cause of human cancer

2000 • 729 citations

Systemic Diseases Caused by Oral Infection

2000 • 684 citations

Sarcoidosis

2003 • 599 citations

Molecular Mimicry and Autoimmunity

1999 • 523 citations

Periodontal Disease and Coronary Heart Disease Risk

2000 • 501 citations

Dental and Cardiac Risk Factors for Infective Endocarditis: A Population-Based, Case-Control Study

1998 • 467 citations

Tourette's Syndrome

2001 • 449 citations

Dentists Are Innocent! ``Everyday'' Bacteremia Is the Real Culprit: A Review and Assessment of the Evidence That Dental Surgical Procedures Are a Principal Cause of Bacterial Endocarditis in Children

1999 • 343 citations

Endodontic infections: Concepts, paradigms, and perspectives

2002 • 333 citations

How important are dental procedures as a cause of infective endocarditis?

1984 • 332 citations

Progress in determining the causes and treatment of multiple sclerosis

1999 • 280 citations

Molecular and Cultural Analysis of the Microflora Associated with Endodontic Infections

2002 • 264 citations

PCR-Based Identification of Bacteria Associated with Endodontic Infections

2002 • 262 citations

Antibiotic prophylaxis for dental patients with total joint replacements

2003 • 251 citations

Neuropathological and computerized tomographic findings in experimental brain abscess

1981 • 231 citations

AUSTRALIA

1980 • 230 citations

The oral cavity as a reservoir of bacterial pathogens for focal infections

2000 • 229 citations

Antimicrobial Prophylaxis in Adults

2011 • 216 citations

RISK FACTORS FOR INFECTIVE ENDOCARDITIS

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A current review of brain abscess

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THE HUMAN MOUTH AS A FOCUS OF INFECTION.

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Procedures associated with infective endocarditis in adults

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Microflora in the healthy gingival sulcus in man

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Pharmacology and therapeutics for dentistry

1982 • 207 citations

Dental Bacteremia in Children

1997 • 193 citations

Periodontitis–systemic disease associations in the presence of smoking – causal or coincidental?

2002 • 186 citations

Antibiotic prophylaxis and the medically compromised patient

1996 • 177 citations

The relationships between streptococcal species and periodontopathic bacteria in human dental plaque

1985 • 176 citations

The Intracranial Complications of Rhinosinusitis: Can They Be Prevented?

2002 • 175 citations

Clinical stages of human brain abscesses on serial CT scans after contrast infusion

1983 • 168 citations

Examining the link between coronary heart disease and the elimination of chronic dental infections

2001 • 147 citations

Pathogenetic role of autoantibodies in neurological diseases

2000 • 145 citations

Root canal therapy

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Analysis of 281,797 Consecutive Blood Cultures Performed over an Eight-Year Period: Trends in Microorganisms Isolated and the Value of Anaerobic Culture of Blood

1997 • 134 citations

CHRONIC FOCAL INFECTIONS AND THEIR ETIOLOGIC RELATIONS TO ARTHRITIS AND NEPHRITIS

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Oral Sepsis as a Cause of Disease

1900 • 129 citations

Infective endocarditis, dentistry and antibiotic prophylaxis; time for a rethink?

2000 • 127 citations

Clinical Significance of Bacteremia Involving the ``Streptococcus milleri'' Group: 51 Cases and Review

1998 • 115 citations

Relation between mouth and haematogenous infection in total joint replacements

1994 • 108 citations

Pre-existing Cardiovascular Disease and Periodontitis: A Follow-up Study

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Systemic diseases caused by oral microorganisms

1994 • 105 citations

Antibiotic prophylaxis: problems in paradise

2003 • 98 citations

Current concepts of bacterial infections of the central nervous system

1983 • 94 citations

Root canal treatment and general health: a review of the literature

2000 • 79 citations

Streptococcal Meningitis in Adult Patients: Current Epidemiology and Clinical Spectrum

1999 • 78 citations

Cost-effectiveness of antibiotic prophylaxis for dental procedures in patients with artificial joints.

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The incidence of bacteremias related to endodontic procedures I. Nonsurgical endodontics

1976 • 70 citations

A history of oral sepsis as a cause of disease

2000 • 68 citations

Anaerobic Bacteremia and Fungemia in Patients Undergoing Endodontic Therapy: An Overview

1998 • 66 citations

The micro-organisms of the human mouth : the local and general diseases which are caused by them

2011 • 64 citations

Infections and course of disease in mild forms of Guillain–Barré syndrome

2002 • 60 citations

FOCAL INFECTION AND SYSTEMIC DISEASE: A CRITICAL APPRAISAL

1940 • 60 citations

Casual or Causal Relationship between Periodontal Infection and Non-oral Disease?

1998 • 57 citations

A retrospective investigation of advanced periodontal disease as a risk factor for septicemia in hematopoietic stem cell and bone marrow transplant recipients

2002 • 55 citations

Incidence of bacteremias related to endodontic procedures.

1977 • 52 citations

CLINICAL AND EXPERIMENTAL OBSERVATIONS ON FOCAL INFECTION, WITH AN ANALYSIS OF 200 CASES OF RHEUMATOID ARTHRITIS

1938 • 51 citations

Prophylactic coverage of dental patients with artificial joints: A retrospective analysis of thirty-three infections in hip prostheses

1980 • 50 citations

Long-Term Follow-Up Evaluation of 1000 Consecutive Cemented Total Knee Arthroplasties

1991 • 48 citations

Pseudomonas aeruginosa Causing a Right Carotid Artery Mycotic Aneurysm After a Dental Extraction Procedure

2002 • 48 citations

Prospective study ofStreptococcus milleri bacteremia

1996 • 46 citations

An Evaluation of the Effect of Dental Foci of Infection on Health

1951 • 46 citations

Dental procedures in children with severe congenital heart disease: a theoretical analysis of prophylaxis and non-prophylaxis procedures

2001 • 41 citations

The Focal Infection Theory: Appraisal and Reappraisal

2000 • 40 citations

Studies on Elective Localization: Focal Infection with Special Reference to Oral Sepsis

1919 • 39 citations

Myths of Dental-Induced Prosthetic Joint Infections

1995 • 38 citations

Focal Infection. The Lane Medical Lectures.

1917 • 36 citations

CHRONIC FOCAL INFECTION AS A CAUSATIVE FACTOR IN CHRONIC ARTHRITIS

1913 • 36 citations

Antimicrobial Prophylaxis in Adults

2000 • 34 citations

Environmental Risk Factors for Amyotrophic Lateral Sclerosis

2001 • 34 citations

Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS)

2002 • 33 citations

Medical theories and professional development

1982 • 32 citations

Dialister pneumosintes can be a suspected endodontic pathogen

2002 • 32 citations

Brain abscess and its surgical management

1982 • 32 citations

Germs, Dr. Billings, and the Theory of Focal Infection

1998 • 30 citations

American Attitudes Toward the Germ Theory of Disease (1860–1880)

1954 • 26 citations

Managing Dental Patients with Joint Prostheses

1994 • 21 citations

Bacteriological analysis of pyogenic infections of the brain

1990 • 19 citations

Brain Abscess

1987 • 19 citations

The Aching Head

1988 • 17 citations

Are All Diseases Infectious? Another Look

1999 • 16 citations

Septic Arthritis Due to Streptococcus sanguis

2002 • 15 citations

Focal Infection*

1942 • 14 citations

William Hunter's "oral sepsis" and American odontology.

1973 • 14 citations

The Role of Sepsis and Antisepsis in Medicine and the Importance of Oral Sepsis as Its Chief Cause.

1911 • 13 citations

Oral Microorganisms and Cardiovascular Disease

2000 • 12 citations

Dental Sepsis: Anaemia, Dyspepsia, and Rheumatism

1939 • 12 citations

Fundamentals Suggested by Recent Researches for Diagnosis, Prognosis, and Treatment of Dental Focal Infections

1925 • 11 citations

Results of Experimental Studies on Focal Infection and Elective Localization11The original paper, of which this is an abstract, was read before the American Medical Association, Boston, 1921, and was published in the Medical Clinics of North America, V (1921), 573–92.

1922 • 11 citations

Endodontic Infections

2012 • 8 citations

Fashions in Pathogenetic Concepts During the Present Century: Autointoxication, Focal Infection, Psychosomatic Disease, and Autoimmunity

1992 • 8 citations

Oral and cardiovascular disease associations do not call for extraction of teeth

2002 • 6 citations

Subject: Resolved, that Practically All Infected Pulpless Teeth Should be Removed**The challenge to debate this question was issued by Dr. Buckley and promptly accepted by Dr. Price.

1925 • 4 citations

Devitalized (Dead) Teeth

1918 • 4 citations

Focal Infection and Systemic Disease

1951 • 4 citations

William Hunter and the role of "oral sepsis" in American dentistry.

1985 • 3 citations

A guide to evaluating epidemiological studies.

2000 • 3 citations

BACTERIAL ENDOCARDITIS

1968 • 2 citations

Dental Sepsis in Relation to Anaemia, Dyspepsia, and Rheumatism, with Particular Reference to Treatment.

1939 • 2 citations

A Guide to Evaluating Epidemiologic Studies

2000 • 1 citations

Antibiotic Prophylaxis

2024 • 1 citations