Safety, Tolerability and Pharmacokinetics of the N‐Methyl‐<scp>d</scp>‐Aspartate Antagonist Ro‐01–6794/706 in Patients with Acute Ischemic Stroke^ab

Measurements of acute cerebral infarction: a clinical examination scale.

1989 • 5,225 citations

Glutamate and the pathophysiology of hypoxic–ischemic brain damage

1986 • 2,428 citations

Blockade of N -Methyl-D-Aspartate Receptors May Protect Against Ischemic Damage in the Brain

1984 • 1,689 citations

Interrater Reliability of the NIH Stroke Scale

1989 • 944 citations

Anticonvulsant Action of Excitatory Amino Acid Antagonists

1982 • 692 citations

Hypoglycemia-Induced Neuronal Damage Prevented by an N -Methyl-D-Aspartate Antagonist

1985 • 673 citations

Possible Therapeutic Applications of Antagonists of Excitatory Amino acid Neurotransmitters

1985 • 558 citations

[³H]MK‐801 Labels a Site on the N‐Methyl‐D‐Aspartate Receptor Channel Complex in Rat Brain Membranes

1988 • 453 citations

A critical appraisal of stroke evaluation and rating scales.

1991 • 174 citations

Dextrorphan and dextromethorphan attenuate glutamate neurotoxicity

1987 • 163 citations

Dextrorphan and levorphanol selectively block N-methyl-D-aspartate receptor-mediated neurotoxicity on cortical neurons.

1987 • 154 citations

Differential effects of dextrorphan and levorphanol on the excitation of rat spinal neurons by amino acids

1985 • 153 citations

Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize in brain slices

1988 • 137 citations

Stereospecific binding of 3H-phencyclidine in brain membranes

1982 • 116 citations

Chronic infusion of endogenous excitatory amino acids into rat striatum and hippocampus

1983 • 110 citations

Delayed treatment with dextromethorphan and dextrorphan reduces cerebral damage after transient focal ischemia

1988 • 102 citations

Protective effect of N-methyl-D-aspartate antagonists after focal cerebral ischemia in rabbits.

1989 • 92 citations

Actions and addiction liabilities of dromoran derivatives in man.

1953 • 91 citations

Dextrorphan and dextromethorphan, common antitussives, are antiepileptic and antagonize N-methyl-D-aspartate in brain slices

1988 • 84 citations

Interaction of dextrorotatory opioids with phencyclidine recognition sites in rat brain membranes

1984 • 69 citations

Chronic infusion ofl-glutamate causes neurotoxicity in rat striatum

1984 • 58 citations

Pretreatment with the NMDA antagonist dextrorphan reduces cerebral injury following transient focal ischemia in rabbits

1989 • 26 citations

A dose-response study of dextrorphan in permanent focal ischemia

1993 • 20 citations

Dextrorphan: An antagonist for phencyclidine receptors

1987 • 6 citations