Striatal Dopamine Dynamics Are Altered Following an Intranigral Infusion of Iron in Adult Rats

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Oxygen toxicity, oxygen radicals, transition metals and disease

1984 • 5,301 citations

Reactive Oxygen Species and the Central Nervous System

1992 • 2,931 citations

Increased Nigral Iron Content and Alterations in Other Metal Ions Occurring in Brain in Parkinson's Disease

1989 • 1,117 citations

Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species.

1993 • 785 citations

Oxidative damage to mitochondrial DNA shows marked age‐dependent increases in human brain

1993 • 759 citations

Parkinson's disease: A disorder due to nigral glutathione deficiency?

1982 • 746 citations

Nafion-coated electrodes with high selectivity for CNS electrochemistry

1984 • 632 citations

Reduced and oxidized glutathione in the substantia nigra of patients with Parkinson's disease

1992 • 575 citations

Selective Increase of Iron in Substantia Nigra Zona Compacta of Parkinsonian Brains

1991 • 516 citations

An introduction to the free radical hypothesis in Parkinson's disease

1992 • 385 citations

Involvement of Free Radicals in Excitotoxicity In Vivo

1995 • 325 citations

Intranigral Iron Injection Induces Behavioral and Biochemical “Parkinsonism” in Rats

1991 • 194 citations

Animal Models of Parkinsonism Using Selective Neurotoxins: Clinical and Basic Implications

1989 • 194 citations

In Vivo Generation of Hydroxyl Radicals and MPTP‐Induced Dopaminergic Toxicity in the Basal Ganglia

1994 • 118 citations

Ferrous‐Citrate Complex and Nigral Degeneration: Evidence for Free‐radical Formation and Lipid Peroxidation^a

1994 • 115 citations

Characterization of the techniques of pressure ejection and microiontophoresis using in vivo electrochemistry

1987 • 96 citations

S-nitrosothiols and nitric oxide, but not sodium nitroprusside, protect nigrostriatal dopamine neurons against iron-induced oxidative stress in vivo

1996 • 91 citations

Iron induces degeneration of nigrostriatal neurons

1992 • 89 citations

Clearance and Diffusion of Locally Applied Dopamine in Normal and 6-Hydroxydopamine-Lesioned Rat Striatum

1994 • 85 citations

Fluorescent and Cross-Linked Proteins Formed by Free Radical and Aldehyde Species Generated during Lipid Oxidation

1990 • 82 citations

Release of Monoamines from Striatum of Rat and Mouse Evoked by Local Application of Potassium: Evaluation of a New In Vivo Electrochemical Technique

1986 • 82 citations

The neurotoxicity of iron and nitric oxide. Relevance to the etiology of Parkinson's disease.

1993 • 74 citations

Nomifensine and its derivatives as possible tools for studying amine

1977 • 73 citations

Progressive Changes in Striatal Dopaminergic Markers, Nigral Volume, and Rotational Behavior Following Iron Infusion into the Rat Substantia Nigra

1994 • 73 citations

Iron-induced lipid peroxidation and inhibition of dopamine synthesis in striatum synaptosomes

1989 • 52 citations

Toxic Effects of Iron for Cultured Mesencephalic Dopaminergic Neurons Derived from Rat Embryonic Brains

1992 • 50 citations

Increased dopamine clearance in the non-lesioned striatum of rhesus monkeys with unilateral 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) striatal lesions

1995 • 26 citations

Chronic effects of single intrastriatal injections of 6-hydroxydopamine or 1-methyl-4-phenylpyridinium studied by microdialysis in freely moving rats

1995 • 25 citations

In vivo electrochemical studies of dopamine diffusion and clearance in the striatum of young and aged Fischer-344 rats

1992 • 22 citations

Dynamic analysis of ethanol effects on NMDA-evoked dopamine overflow in rat striatum

1995 • 14 citations

Dimethylthiourea prevents MPTP-induced decrease in [3H]dopamine uptake in rat striatal slices

1995 • 8 citations