Effective treatment of a mouse model of Sjögren's syndrome with eyedrop administration of anti‐CD4 monoclonal antibody

N<scp>aturally</scp>A<scp>rising</scp>CD4⁺R<scp>egulatory</scp>T C<scp>ells for</scp>I<scp>mmunologic</scp>S<scp>elf</scp>-T<scp>olerance and</scp>N<scp>egative</scp>C<scp>ontrol of</scp>I<scp>mmune</scp>R<scp>esponses</scp>

2003 • 3,323 citations

Positive and Negative Selection of T Cells

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T Cell Anergy

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MATURE T LYMPHOCYTE APOPTOSIS—Immune Regulation in a Dynamic and Unpredictable Antigenic Environment

1999 • 973 citations

Autoimmune Diseases

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Autoimmune disease: why and where it occurs

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Mutation of DNASE1 in people with systemic lupus erythematosus

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Delineating the Genetic Basis of Systemic Lupus Erythematosus

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SELECTION OF THE T CELL REPERTOIRE

1999 • 507 citations

The Regulatory T Cell Family: Distinct Subsets and their Interrelations

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Memory CD4+ T cells do not induce graft-versus-host disease

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Identification of α-Fodrin as a Candidate Autoantigen in Primary Sjögren's Syndrome

1997 • 400 citations

Analysis of Topical Cyclosporine Treatment of Patients With Dry Eye Syndrome&lt;subtitle&gt;Effect on Conjunctival Lymphocytes&lt;/subtitle&gt;

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Increased fluid secretion after adenoviral-mediated transfer of the aquaporin-1 cDNA to irradiated rat salivary glands

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Update in Sjögren syndrome

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The Efficiency of CD4 Recruitment to Ligand-engaged TCR Controls the Agonist/Partial Agonist Properties of Peptide–MHC Molecule Ligands

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Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity

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Cathepsin S inhibitor prevents autoantigen presentation and autoimmunity

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A new animal model for primary Sjögren's syndrome in NFS/sld mutant mice.

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Autoantibodies in Primary Sjögren's Syndrome: New Insights into Mechanisms of Autoantibody Diversification and Disease Pathogenesis

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Chemokines and Cell Trafficking in Sjögren's Syndrome

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Induction of Experimental Autoallergic Sialadenitis

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Prevention and Induction of Autoimmune Exocrinopathy Is Dependent on Pathogenic Autoantigen Cleavage in Murine Sjögren’s Syndrome

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In Vivo use of monoclonal antibodies against murine T cell antigens

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Anti–α-Fodrin Antibodies in Sjögren Syndrome and Lupus Erythematosus

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T cell attractant chemokine expression initiates lacrimal gland destruction in nonobese diabetic mice.

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Treatment with anti-CD86 costimulatory molecule prevents the autoimmune lesions in murine Sjögren’s syndrome (SS) through up-regulated Th2 response

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Transfer of Sjögren's syndrome‐like autoimmune lesions into SCID mice and prevention of lesions by anti‐CD4 and anti‐T cell receptor antibody treatment

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Correlation of increased susceptibility to apoptosis of CD4+ T cells with lymphocyte activation and activity of disease in patients with primary Sj�gren's syndrome

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Pathological lymphocyte activation by defective clearance of self-ligands in systemic lupus erythematosus

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A new mutation involving the sublingual gland in NFS/N mice. Partially arrested mucous cell differentiation.

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Pathogenesis of Sjögren's syndrome‐like autoimmune lesions in MRL/Ipr mice

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Use of topical cyclosporin A in a primary Sjögren's syndrome mouse model.

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Sjögren's Syndrome: Pathogenesis

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Successful Transfer of Localized Autoimmunity with Positively Selected CD4 ⁺ Cells to scid Mice Lacking Functional B Cells

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