Kinetic Evaluation of [¹¹C]Dihydrotetrabenazine by Dynamic PET: Measurement of Vesicular Monoamine Transporter

Data Reduction and Error Analysis for the Physical Sciences

1969 • 13,865 citations

A quantitative model for the in vivo assessment of drug binding sites with positron emission tomography

1984 • 959 citations

Dopamine visualized in the basal ganglia of living man

1983 • 643 citations

Single photon emission computed tomographic imaging demonstrates loss of striatal dopamine transporters in Parkinson disease.

1993 • 363 citations

Compartmental Analysis of [¹¹C]Flumazenil Kinetics for the Estimation of Ligand Transport Rate and Receptor Distribution Using Positron Emission Tomography

1991 • 344 citations

Positron emission tomographic imaging of the dopamine transporter with ¹¹C‐WIN 35,428 reveals marked declines in mild Parkinson's disease

1993 • 319 citations

Graphical, Kinetic, and Equilibrium Analyses of in vivo [¹²³I]β-CIT Binding to Dopamine Transporters in Healthy Human Subjects

1994 • 274 citations

The vesicular monoamine transporter is not regulated by dopaminergic drug treatments

1995 • 199 citations

Strategy for the Measurement of Regional Cerebral Blood Flow Using Short-Lived Tracers and Emission Tomography

1984 • 177 citations

Dopa decarboxylase activity of the living human brain.

1991 • 172 citations

Kinetics and Modeling of l-6-[¹⁸F]Fluoro-DOPA in Human Positron Emission Tomographic Studies

1991 • 168 citations

Radioligands of the vesicular monoamine transporter and their use as markers of monoamine storage vesicles

1989 • 164 citations

Heterogeneous subregional binding patterns of 3H-WIN 35,428 and 3H-GBR 12,935 are differentially regulated by chronic cocaine self- administration

1994 • 146 citations

In vivoevaluation of striatal dopamine reuptake sites using 11C-nomifensine and positron emission tomography

1987 • 146 citations

The Vesicular Monoamine Transporter, in Contrast to the Dopamine Transporter, Is Not Altered by Chronic Cocaine Self-Administration in the Rat

1996 • 126 citations

Aromatic L‐Amino Acid Decarboxylase Activity of Mouse Striatum Is Modulated via Dopamine Receptors

1993 • 118 citations

Regulation of Aromatic <scp>l</scp>‐Amino Acid Decarboxylase by Dopamine Receptors in the Rat Brain

1992 • 112 citations

Withdrawal of repeated cocaine decreases autoradlographic [3H]mazindol-labelling of dopamine transporter In rat nucleus aecumbens

1991 • 108 citations

In vivo Muscarinic Cholingeric Receptor Imaging in Human Brain with [¹¹C]Scopolamine and Positron Emission Tomography

1992 • 101 citations

[3H]methoxytetrabenazine: A high specific activity ligand for estimating monoaminergic neuronal integrity

1995 • 98 citations

Binding of α-dihydrotetrabenazine to the vesicular monoamine transporter is stereospecific

1995 • 94 citations

[³H]Dihydrotetrabenazine, a New In Vitro Monoaminergic Probe for Human Brain

1988 • 84 citations

Striatal L‐DOPA Decarboxylase Activity in Parkinson's Disease In Vivo: Implications for the Regulation of Dopamine Synthesis

1993 • 73 citations

[¹¹C]Tropanyl Benzilate—Binding to Muscarinic Cholinergic Receptors: Methodology and Kinetic Modeling Alternatives

1994 • 72 citations

A Two-Compartment Description and Kinetic Procedure for Measuring Regional Cerebral [¹¹C]Nomifensine Uptake Using Positron Emission Tomography

1990 • 66 citations

Chronic L-deprenyl-induced up-regulation of the dopamine uptake carrier

1989 • 59 citations

Repeated reserpine administration reduces in vivo [18F]GBR 13119 binding to the dopamine uptake site

1992 • 54 citations

Short-term treatments with haloperidol or bromocriptine do not alter the density of the monoamine vesicular transporter in the substantia nigra

1994 • 54 citations

In vivo binding of [11C]tetrabenazine to vesicular monoamine transporters in mouse brain

1992 • 50 citations

[3H]Dihydrotetrabenazine, a new marker for the visualization of dopaminergic denervation in the rat striatum

1990 • 47 citations

[3H]Dihydrotetrabenazine binding to bovine striatal synaptic vesicles.

1986 • 39 citations

Striatal monoamine neurotransmitters and metabolites in dominantly inherited olivopontocerebellar atrophy

1992 • 37 citations

Neuropeptide-dopamine interactions. V. Cyclo(His-Pro) regulation of striatal dopamine transporter complex

1990 • 35 citations