Detection and expression of a cDNA clone that encodes a polypeptide containing two inhibitory domains of human calpastatin and its recognition by rheumatoid arthritis sera.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis

1988 • 19,632 citations

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

1988 • 6,107 citations

Calcium-activated neutral protease (calpain) system: structure, function, and regulation.

1991 • 841 citations

Evidence for metalloproteinase and metalloproteinase inhibitor imbalance in human osteoarthritic cartilage.

1989 • 604 citations

Calpain activation in apoptosis

1994 • 445 citations

Cartilage in health and disease

1997 • 270 citations

The cytokeratin filament-aggregating protein filaggrin is the target of the so-called "antikeratin antibodies," autoantibodies specific for rheumatoid arthritis.

1993 • 259 citations

Autoantibodies in pathology and cell biology

1991 • 250 citations

Expression of Metalloproteinases and Metalloproteinase Inhibitor in Human Arthritic Synovium

1991 • 217 citations

Immune Mechanisms In Graves' Disease

1985 • 217 citations

Involvement of the chaperonin dnaK in the rapid degradation of a mutant protein in Escherichia coli.

1992 • 199 citations

The Sa system: a novel antigen-antibody system specific for rheumatoid arthritis.

1994 • 185 citations

The Role of Autoantibodies in Autoimmune Disease

1993 • 184 citations

Cytokines and proteases in invasive processes: Molecular similarities between inflammation and cancer

1992 • 160 citations

Cysteine Proteinase Inhibitors Decrease Articular Cartilage and Bone Destruction in Chronic Inflammatory Arthritis

1994 • 124 citations

Modulation of Cellular Signals by Calpain

1992 • 117 citations

Fucose-containing oligosaccharides from human milk from a donor of blood group 0 Le(a) nonsecretor.

1988 • 115 citations

Purification and partial sequencing of the nuclear autoantigen RA33 shows that it is indistinguishable from the A2 protein of the heterogeneous nuclear ribonucleoprotein complex.

1992 • 103 citations

Antiperinuclear factor, a marker autoantibody for rheumatoid arthritis: colocalisation of the perinuclear factor and profilaggrin.

1991 • 97 citations

All four repeating domains of the endogenous inhibitor for calcium-dependent protease independently retain inhibitory activity. Expression of the cDNA fragments in Escherichia coli.

1988 • 86 citations

Interference of Wegener's granulomatosis autoantibodies with neutrophil Proteinase 3 activity

1992 • 85 citations

cDNA Cloning of Human Calpastatin: Sequence Homology Among Human, Pig, and Rabbit Calpastatins

1989 • 62 citations

Calcium‐dependent cysteine proteinase (calpain) in human arthritic synovial joints

1992 • 60 citations

Stimulation of the secretion of latent cysteine proteinase activity by tumor necrosis factor α and interleukin‐1

1993 • 57 citations

Biochemical demonstration of calpains and calpastatin in osteoarthritic synovial fluid

1990 • 47 citations

Extracellular appearance of calpain and calpastatin in the synovial fluid of the knee joint

1989 • 47 citations

Myasthenia Gravis: Prototype of the Antireceptor Autoimmune Diseases

1990 • 47 citations

Determination of Cathepsins B and H in Sera and Synovial Fluids of Patients with Different Joint Diseases

1990 • 42 citations

Isolation and characterization of cDNA clones for human erythrocyte beta-spectrin.

1987 • 41 citations

Characterization of proteoglycan degradation by calpain

1992 • 40 citations

Measurement of Elastase and Cysteine Proteinases in Synovial Fluid of Patients with Rheumatoid Arthritis, Sero-Negative Spondylarthropathies, and Osteoarthritis

1992 • 33 citations

MOLECULAR BIOLOGY OF NUCLEAR AUTO ANTIGENS

1992 • 23 citations

Enzyme immunoassay for cathepsins B and L in synovial fluids from patients with arthritis

1988 • 19 citations

Autoantibody-facilitated proteolytic cleavage: a new pathogenic mechanism in autoimmunity

1991 • 2 citations