Identification of Differentially Expressed Genes in Cardiac Hypertrophy by Analysis of Expressed Sequence Tags

Basic local alignment search tool

1990 • 87,358 citations

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction

1987 • 45,673 citations

Prognostic Implications of Echocardiographically Determined Left Ventricular Mass in the Framingham Heart Study

1990 • 5,586 citations

Serial Analysis of Gene Expression

1995 • 3,659 citations

Complementary DNA Sequencing: Expressed Sequence Tags and Human Genome Project

1991 • 2,286 citations

Identification of protein coding regions by database similarity search

1993 • 1,660 citations

Protooncogene induction and reprogramming of cardiac gene expression produced by pressure overload.

1988 • 877 citations

THE CELLULAR AND MOLECULAR RESPONSE OF CARDIAC MYOCYTES TO MECHANICAL STRESS

1997 • 876 citations

Initial assessment of human gene diversity and expression patterns based upon 83 million nucleotides of cDNA sequence.

1995 • 804 citations

Sequence identification of 2,375 human brain genes

1992 • 764 citations

Rapid transcriptional activation and early mRNA turnover of brain natriuretic peptide in cardiocyte hypertrophy. Evidence for brain natriuretic peptide as an "emergency" cardiac hormone against ventricular overload.

1995 • 621 citations

Large scale cDNA sequencing for analysis of quantitative and qualitative aspects of gene expression

1992 • 528 citations

Generation and analysis of 280,000 human expressed sequence tags.

1996 • 474 citations

Construction and characterization of a normalized cDNA library.

1994 • 411 citations

Rapid cDNA sequencing (expressed sequence tags) from a directionally cloned human infant brain cDNA library

1993 • 361 citations

Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing.

1997 • 328 citations

Analysis of an expression profile of genes in the human adipose tissue

1997 • 293 citations

3,400 new expressed sequence tags identify diversity of transcripts in human brain

1993 • 292 citations

Single pass sequencing and physical and genetic mapping of human brain cDNAs

1992 • 173 citations

A Genome-Based Resource for Molecular Cardiovascular Medicine

1997 • 171 citations

A pancreatic cancer-specific expression profile.

1996 • 160 citations

Discovery of three genes specifically expressed in human prostate by expressed sequence tag database analysis

1998 • 148 citations

Identification of genes expressed in human CD34⁺hematopoietic stem/progenitor cells by expressed sequence tags and efficient full-length cDNA cloning

1998 • 131 citations

Higher antioxidative capacity during a chronic stable heart hypertrophy.

1989 • 116 citations

Alterations in Gene Expression in the Rat Heart After Chronic Pathological and physiological Loads

1994 • 116 citations

A catalogue of genes in the cardiovascular system as identified by expressed sequence tags.

1994 • 100 citations

Differential Expression of αB-Crystallin and Hsp27 in Skeletal Muscle during Continuous Contractile Activity

1996 • 99 citations

Isolation of differentially expressed sequence tags from human breast cancer.

1994 • 95 citations

The Genexpress Index: a resource for gene discovery and the genic map of the human genome.

1995 • 90 citations

Complement Gene Expression by Rabbit Heart

1998 • 90 citations

Gene Expression in Proliferating Human Erythroid Cells

1999 • 82 citations

Human cochlear expressed sequence tags provide insight into cochlear gene expression and identify candidate genes for deafness

1999 • 74 citations

A molecular inventory of human pancreatic islets: sequence analysis of 1000 cDNA clones

1993 • 74 citations

Expression Profile of Active Genes in Granulocytes

1998 • 69 citations

A gene expression profile of human corneal epithelium and the isolation of human keratin 12 cDNA.

1996 • 68 citations

Regulation of Ribosomal DNA Transcription during Contraction-induced Hypertrophy of Neonatal Cardiomyocytes

1996 • 67 citations

Construction of a representative cDNA library from prostatic intraepithelial neoplasia.

1996 • 66 citations

Expressed sequence tags and chromosomal localization of cDNA clones from a subtracted retinal pigment epithelium library

1992 • 64 citations

Expression profiles of active genes in human and mouse livers

1996 • 63 citations

Prostaglandin D ₂ Inhibits Inducible Nitric Oxide Synthase Expression in Rat Vascular Smooth Muscle Cells

1998 • 59 citations

An Expressed-Sequence-Tag Database of the Human Prostate: Sequence Analysis of 1168 cDNA Clones

1998 • 56 citations

Molecular and cellular biology of heart failure

1996 • 51 citations

Characterization of a Human Fovea cDNA Library and Regional Differential Gene Expression in the Human Retina

1996 • 48 citations

Identification and Cloning of Neuroblastoma-Specific and Nerve Tissue-Specific Genes through Compiled Expression Profiles

1996 • 48 citations

Analysis of a sequenced cDNA library from multiple sclerosis lesions

1997 • 44 citations

HSP27 locus cosegregates with left ventricular mass independently of blood pressure.

1996 • 44 citations

Characterization of a large population of mRNAs from human testis

1995 • 42 citations

Analysis of 2166 clones from a human colorectal cancer cDNA library by partial sequencing

1995 • 42 citations

Monitoring Cell Physiology by Expression Profiles and Discovering Cell Type-Specific Genes by Compiled Expression Profiles

1995 • 38 citations

Analysis of Expressed Sequence Tags from a Fetal Human Heart cDNA Library

1995 • 38 citations

Single Pass Sequencing of a Unidirectional Human Fetal Heart cDNA Library to Discover Novel Genes of the Cardiovascular System

1994 • 38 citations

Congestive heart failure: increased cardiac and extracardiac atrial natriuretic peptide gene expression

1996 • 36 citations

An expression profile of genes in human retina and isolation of a complementary DNA for a novel rod photoreceptor protein.

1997 • 35 citations

Prostate Cancer Expression Profiling by cDNA Sequencing Analysis

1999 • 35 citations

Identification of genes differentially expressed in normal lung and non-small cell lung carcinoma tissue

1995 • 33 citations

The Identification of Novel Gene Sequences of the Human Adult Testis

1994 • 33 citations

Endogenous antioxidants in isolated hypertrophied cardiac myocytes and hypoxia-reoxygenation injury

1995 • 29 citations

Effect of PGD2 on cardiac contractility: a negative inotropism secondary to coronary vasoconstriction conceals a primary positive inotropic action.

1986 • 29 citations

2058 Expressed Sequence Tags (ESTs) from a Human Fetal Lung cDNA Library

1994 • 29 citations

Construction of a Normalized Directionally Cloned cDNA Library from Adult Heart and Analysis of 3040 Clones by Partial Sequencing

1996 • 25 citations

An Expression Profile of Active Genes in Human Colonic Mucosa

1994 • 24 citations

Chromosomal Assignments of 3′-Directed Partial cDNA Sequences Representing Novel Genes Expressed in Granulocytoid Cells

1994 • 24 citations

Functional quantitative analysis of the genome in cultured human mesangial cells: Technical Note

1998 • 24 citations

Mapping Novel Pancreatic Islet Genes to Human Chromosomes

1997 • 22 citations

A Human Heart cDNA Library—The Development of an Efficient and Simple Method for Automated DNA sequencing

1993 • 20 citations

Identification of Sequence-Tagged Transcripts Differentially Expressed within the Human Hematopoietic Hierarchy

1998 • 18 citations

An Expression Profile of Active Genes in Human Lung

1994 • 17 citations

Construction of a gene expression profile of a human fetal liver by single-pass cDNA sequencing

1995 • 17 citations

The preliminary transcript map of a human skeletal muscle

1997 • 17 citations

Increased gene expression of plasminogen activators and inhibitors in left ventricular hypertrophy

1997 • 16 citations

Cataloging of the Genes Expressed in Human Keratinocytes: Analysis of 607 Randomly Isolated cDNA Sequences

1994 • 16 citations

Isolation and Regional Mapping of cDNAs Expressed during Early Human Development

1997 • 15 citations

Untitled

1997 • 14 citations

Human CD34+ cell EST database: single-pass sequencing of 402 clones from a directional cDNA library.

1996 • 14 citations

Expression and chromosomal localization of cDNA clones from an enriched human retinal pigment epithelial (RPE) cell line library: identification of two RPE-specific genes

1995 • 13 citations

Inotropic Effects of Prostaglandin D2 and E1 on the Newborn Rabbit Heart

1984 • 11 citations

An Expression Profile of Active Genes in Cultured Human Keratinocytes

1996 • 9 citations

Toward Molecular Strategies for Heart Disease

1997 • 9 citations

Sequence analysis of libraries from individual human blastocysts.

1998 • 8 citations

Chromosomal localization and expressed sequence tag generation of clones from a normalized human adult thymus cDNA library.

1995 • 7 citations

Secretion of Cardiac Plasminogen Activator During Hypoxia-induced Right Ventricular Hypertrophy

1997 • 7 citations

Generation and chromosome mapping of expressed sequence tags (ESTs) from a human infant thymus

1999 • 5 citations