Anti-MUC-1 immunoliposomal doxorubicin in the treatment of murine models of metastatic breast cancer

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Selective events in the metastatic process defined by analysis of the sequential dissemination of subpopulations of a mouse mammary tumor.

1992 • 1,217 citations

Microvascular permeability and interstitial penetration of sterically stabilized (stealth) liposomes in a human tumor xenograft.

1994 • 904 citations

Interstitial pressure gradients in tissue-isolated and subcutaneous tumors: implications for therapy.

1990 • 742 citations

Identification and characterization of the blood vessels of solid tumors that are leaky to circulating macromolecules.

1988 • 680 citations

Liposomal doxorubicin: antitumor activity and unique toxicities during two complementary phase I studies.

1995 • 476 citations

Specific, major histocompatibility complex-unrestricted recognition of tumor-associated mucins by human cytotoxic T cells.

1989 • 453 citations

Demonstration of an extensive trans-tubular network continuous with the Golgi apparatus stack that may function in glycosylation

1985 • 448 citations

Doxorubicin Encapsulated in Liposomes Containing Surface‐Bound Polyethylene Glycol: Pharmacokinetics, Tumor Localization, and Safety in Patients with AIDS‐Related Kaposi's Sarcoma

1996 • 370 citations

Increased microvascular permeability contributes to preferential accumulation of Stealth liposomes in tumor tissue.

1993 • 368 citations

Attachment of antibodies to sterically stabilized liposomes: evaluation, comparison and optimization of coupling procedures

1995 • 312 citations

A new strategy for attachment of antibodies to sterically stabilized liposomes resulting in efficient targeting to cancer cells

1995 • 286 citations

Limitations of radiolabeled monoclonal antibodies for localization of human neoplasms.

1986 • 283 citations

In vitro and in vivo targeting of immunoliposomal doxorubicin to human B-cell lymphoma.

1998 • 260 citations

Development of anti-p185HER2 immunoliposomes for cancer therapy.

1995 • 258 citations

Phase I/II clinical and pharmacokinetic evaluation of liposomal daunorubicin.

1995 • 243 citations

Antibody-targeted delivery of doxorubicin entrapped in sterically stabilized liposomes can eradicate lung cancer in mice.

1993 • 239 citations

Endocytosis of liposomes by macrophages: binding, acidification and leakage of liposomes monitored by a new fluorescence assay

1990 • 199 citations

Ammonium Sulfate Gradients for Efficient and Stable Remote Loading of Amphipathic Weak Bases into Liposomes and Ligandoliposomes.

1994 • 195 citations

Targeting cancer micrometastases with monoclonal antibodies: a binding-site barrier.

1995 • 182 citations

Targeting of stealth liposomes to erbB-2 (Her/2) receptor: in vitro and in vivo studies

1996 • 179 citations

An analysis of monoclonal antibody distribution in microscopic tumor nodules: consequences of a "binding site barrier".

1991 • 170 citations

Efficacy of pegylated-liposomal doxorubicin in the treatment of AIDS-related Kaposi's sarcoma after failure of standard chemotherapy.

1997 • 170 citations

The epithelial sialomucin, episialin, is sialylated during recycling.

1993 • 148 citations

Serum sialyl Tn as an independent predictor of poor prognosis in patients with epithelial ovarian cancer.

1992 • 147 citations

Therapeutic opportunities for targeted liposomal drug delivery

1996 • 125 citations

Anti-HER2 immunoliposomes for targeted therapy of human tumors

1997 • 122 citations

Immunogenicity of synthetic peptides related to the core peptide sequence encoded by the human MUC1 mucin gene: Effect of immunization on the growth of murine mammary adenocarcinoma cells transfected with the human MUC1 gene

1993 • 114 citations

Characterization of In Vivo Immunoliposome Targeting to Pulmonary Endothelium

1990 • 112 citations

Human B-cell immune response to the polymorphic epithelial mucin.

1993 • 109 citations

Arrest of human lung tumor xenograft growth in severe combined immunodeficient mice using doxorubicin encapsulated in sterically stabilized liposomes.

1993 • 104 citations

Efficacy and safety of Stealth liposomal doxorubicin in AIDS-related Kaposi's sarcoma

1996 • 103 citations

Anthracyclines in haematology: preclinical studies, toxicity and delivery systems

1997 • 96 citations

Pre-immunotherapy serum CA27.29 (MUC-1) mucin level and CD69 + lymphocytes correlate with effects of Theratope® sialyl-Tn-KLH cancer vaccine in active specific immunotherapy

1996 • 86 citations

Immunoliposome-mediated targeting of doxorubicin to human ovarian carcinoma in vitro and in vivo

1996 • 77 citations

Preferential growth of mammary tumors in intact mammary fatpads.

1981 • 75 citations

Immunogenicity and antitumor activity of a liposomal MUC1 peptide-based vaccine

1998 • 74 citations

Cellular Trafficking and Cytotoxicity of Anti-Cd19-Targeted Liposomal Doxorubicin in B Lymphoma Cells

1999 • 71 citations

Targeted delivery of doxorubicin via sterically stabilized immunoliposomes: pharmacokinetics and biodistribution in tumor-bearing mice.

1996 • 64 citations

Immunoliposome-mediated targeting of anti-cancer drugs in vivo

1995 • 59 citations

High molecular weight epithelial mucins as markers in breast cancer

1988 • 32 citations

Specific targeting of human hepatocellular carcinoma cells by immunoliposomes in vitro

1995 • 29 citations

Possible Utility of Serum Determinations of CA 125 and CA 27.29 in Breast Cancer Management

1991 • 26 citations

Effective drug-antibody targeting using a novel monoclonal antibody against the proliferative compartment of mammalian squamous carcinomas

1990 • 19 citations

A murine monoclonal antibody, MoAb HMSA-5, against a melanosomal component highly expressed in early stages, and common to normal and neoplastic melanocytes

1993 • 18 citations

Therapeutic agents for treatment of established metastases and inhibitors of metastatic spread

1992 • 15 citations