Differential inhibition of cellular and viral pp60src kinase by P1,P4-di(adenosine-5')tetraphosphate.

Statistical estimations in enzyme kinetics

1961 • 3,586 citations

Transforming gene product of Rous sarcoma virus phosphorylates tyrosine

1980 • 2,387 citations

Protein kinase activity associated with the avian sarcoma virus src gene product.

1978 • 1,137 citations

Identification of a transformation-specific antigen induced by an avian sarcoma virus

1977 • 931 citations

Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein

1978 • 673 citations

Structure and sequence of the cellular gene homologous to the RSV src gene and the mechanism for generating the transforming virus

1983 • 586 citations

Evidence that the phosphorylation of tyrosine is essential for cellular transformation by Rous sarcoma virus

1980 • 560 citations

Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src).

1979 • 378 citations

Characterization of sites for tyrosine phosphorylation in the transforming protein of Rous sarcoma virus (pp60v-src) and its normal cellular homologue (pp60c-src).

1981 • 363 citations

The transforming proteins of Rous sarcoma virus, Harvey sarcoma virus and Abelson virus contain tightly bound lipid

1982 • 357 citations

Analysis of the sequence of amino acids surrounding sites of tyrosine phosphorylation.

1982 • 337 citations

Presence of diadenosine 5',5''' -P1, P4-tetraphosphate (Ap4A) in mamalian cells in levels varying widely with proliferative activity of the tissue: a possible positive "pleiotypic activator".

1976 • 269 citations

The purified product of the transforming gene of avian sarcoma virus phosphorylates tyrosine.

1980 • 269 citations

Characterization of a normal avian cell protein related to the avian sarcoma virus transforming gene product

1978 • 251 citations

Evidence that the avian sarcoma virus transforming gene product is a cyclic AMP-independent protein kinase.

1979 • 232 citations

A normal cell protein similar in structure and function to the avian sarcoma virus transforming gene product.

1979 • 187 citations

DNA sequence of the viral and cellular src gene of chickens. II. Comparison of the src genes of two strains of avian sarcoma virus and of the cellular homolog

1982 • 136 citations

Cellular information in the genome of recovered avian sarcoma virus directs the synthesis of transforming protein.

1979 • 132 citations

Identification of a Rous sarcoma virus transformation-related protein in normal avian and mammalian cells.

1979 • 112 citations

Only membrane-associated RSV src proteins have amino-terminally bound lipid

1983 • 107 citations

Viral and cellular src genes contribute to the structure of recovered avian sarcoma virus transforming protein

1981 • 104 citations

Peptide analysis of the transformation-specific antigen from avian sarcoma virus-transformed cells

1978 • 85 citations

Purification of a tyrosine-specific protein kinase from Rous sarcoma virus-induced rat tumor.

1982 • 69 citations

Diadenosine tetraphosphatase from human leukemia cells. Purification to homogeneity and partial characterization.

1983 • 67 citations

Characterization of the protein kinase activity of avian sarcoma virus src gene product.

1979 • 48 citations

P1,P4-Di(adenosine-5')tetraphosphate inhibits phosphorylation of immunoglobulin G by Rous sarcoma virus pp60src.

1983 • 47 citations

9 Functions and Origins of Retroviral Transforming Genes

1982 • 44 citations

Highly Purified pp60^srcInduces the Actin Transformation in Microinjected Cells and Phosphorylates Selected Cytoskeletal Proteins In Vitro

1983 • 30 citations