Purification of a tyrosine-specific protein kinase from Rous sarcoma virus-induced rat tumor.
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References (47)
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Abelson murine leukaemia virus protein is phosphorylated in vitro to form phosphotyrosine
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Avian sarcoma virus-transforming protein, pp60src shows protein kinase activity specific for tyrosine
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Changes in protein phosphorylation in Rous sarcoma virus-transformed chicken embryo cells.
1981 • 440 citations
Uninfected vertebrate cells contain a protein that is closely related to the product of the avian sarcoma virus transforming gene (src).
1979 • 378 citations
The specific interaction of the Rous sarcoma virus transforming protein, pp60src, with two cellular proteins
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Characterization of Rous sarcoma virus src gene products synthesized in vitro
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Adhesion plaques of Rous sarcoma virus-transformed cells contain the src gene product.
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Transformation by Rous sarcoma virus: A cellular substrate for transformation-specific protein phosphorylation contains phosphotyrosine
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Structural analysis of the avian sarcoma virus transforming protein: sites of phosphorylation
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The protein encoded by the transforming gene of avian sarcoma virus (pp60src) and a homologous protein in normal cells (pp60proto-src) are associated with the plasma membrane.
1980 • 298 citations
Transformation by Rous sarcoma virus: effects of src gene expression on the synthesis and phosphorylation of cellular polypeptides.
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Localization of the ASV src gene product to the plasma membrane of transformed cells by electron microscopic immunocytochemistry
1979 • 276 citations
The purified product of the transforming gene of avian sarcoma virus phosphorylates tyrosine.
1980 • 269 citations
Identification of a polypeptide encoded by the avian sarcoma virus src gene.
1978 • 266 citations
Characterization of a normal avian cell protein related to the avian sarcoma virus transforming gene product
1978 • 251 citations
A cellular protein that associates with the transforming protein of Rous sarcoma virus is also a heat-shock protein.
1981 • 246 citations
Evidence that the avian sarcoma virus transforming gene product is a cyclic AMP-independent protein kinase.
1979 • 232 citations
A normal cell protein similar in structure and function to the avian sarcoma virus transforming gene product.
1979 • 187 citations
Evidence that the src gene product of rous sarcoma virus is membrane associated
1980 • 180 citations
Association of the src gene product of Rous sarcoma virus with cytoskeletal structures of chicken embryo fibroblasts.
1980 • 169 citations
Immunofluorescence on avian sarcoma virus-transformed cells: Localization of the src gene product
1979 • 133 citations
Cellular information in the genome of recovered avian sarcoma virus directs the synthesis of transforming protein.
1979 • 132 citations
Translation of 35S and of subgenomic regions of avian sarcoma virus RNA.
1977 • 125 citations
Evidence that the Abelson virus protein functions in vivo as a protein kinase that phosphorylates tyrosine.
1981 • 113 citations
Identification of a Rous sarcoma virus transformation-related protein in normal avian and mammalian cells.
1979 • 112 citations
Properties of the src kinase purified from Rous sarcoma virus-induced rat tumors.
1982 • 108 citations
src gene product from different strains of avain sarcoma virus: Kinetics and possible mechanism of heat inactivation of protein kinase activity from cells infected by transformation-defective, temperature-sensitive mutant and wild-type virus
1979 • 101 citations
Characterization of an immune complex kinase in immunoprecipitates of avian sarcoma virus-transformed fibroblasts
1979 • 99 citations
Transforming proteins of some feline and avian sarcoma viruses are related structurally and functionally
1981 • 85 citations
Differences in intracellular location of pp60src in rat and chicken cells transformed by Rous sarcoma virus.
1980 • 69 citations
Characterization of the avian sarcoma virus protein p60src
1978 • 63 citations
Relationship of polypeptide products of the transforming gene of Rous sarcoma virus and the homologous gene of vertebrates
1980 • 61 citations
Characterization of the protein kinase activity of avian sarcoma virus src gene product.
1979 • 48 citations
Identification of a transformation-specific protein induced by a rous sarcoma virus
1978 • 46 citations
Biochemical characterization of pp60src-associated protein kinase from avian sarcoma virus Schmidt-Ruppin strain.
1981 • 26 citations
Multiple forms of sarc gene proteins from Rous sarcoma virus RNA.
1978 • 25 citations
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