Multiple, targeted deficiencies in selectins reveal a predominant role for P-selectin in leukocyte recruitment

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues

2013 • 47,043 citations

Identification of an inducible endothelial-leukocyte adhesion molecule.

1987 • 1,639 citations

A cell-surface molecule involved in organ-specific homing of lymphocytes

1983 • 1,515 citations

Leukocyte rolling and extravasation are severely compromised in P selectin-deficient mice

1993 • 1,058 citations

α4 integrins mediate lymphocyte attachment and rolling under physiologic flow

1995 • 1,018 citations

Mechanisms That Regulate the Function of the Selectins and Their Ligands

1999 • 931 citations

Lymphocyte homing and leukocyte rolling and migration are impaired in L-selectin-deficient mice

1994 • 835 citations

The integrin VLA-4 supports tethering and rolling in flow on VCAM-1.

1995 • 716 citations

Sequential contribution of L- and P-selectin to leukocyte rolling in vivo.

1995 • 597 citations

Susceptibility to Infection and Altered Hematopoiesis in Mice Deficient in Both P- and E-Selectins

1996 • 534 citations

Infectious susceptibility and severe deficiency of leukocyte rolling and recruitment in E-selectin and P-selectin double mutant mice.

1996 • 391 citations

Characterization of E-selectin-deficient mice: Demonstration of overlapping function of the endothelial selectins

1994 • 384 citations

Distinct Phenotype of E-Selectin–Deficient Mice

1996 • 338 citations

Expression of VCAM-1 and E-selectin in an in vivo model of endothelial activation.

1993 • 223 citations

L-selectin and very late antigen-4 integrin promote eosinophil rolling at physiological shear rates in vivo.

1994 • 199 citations

Mice Lacking Two or All Three Selectins Demonstrate Overlapping and Distinct Functions for Each Selectin

1999 • 189 citations

P-selectin must extend a sufficient length from the plasma membrane to mediate rolling of neutrophils.

1995 • 186 citations

Molecular cloning and analysis of in vivo expression of murine P- selectin

1992 • 165 citations

Genomic organization of the selectin family of leukocyte adhesion molecules on human and mouse chromosome 1.

1990 • 160 citations

Eosinophil adhesion to nasal polyp endothelium is P-selectin-dependent.

1994 • 145 citations

Blood cell dynamics in P-selectin-deficient mice

1995 • 119 citations

Role of Primary and Secondary Capture for Leukocyte Accumulation In Vivo

1998 • 100 citations

Inhibition of Eosinophil Rolling and Recruitment in P-Selectin– and Intracellular Adhesion Molecule-1–Deficient Mice

1998 • 97 citations

Velocity differences between L- and P-selectin-dependent neutrophil rolling in venules of mouse cremaster muscle in vivo

1996 • 95 citations

Blood cell dynamics in P-selectin-deficient mice

1995 • 93 citations

The faster kinetics of L-selectin than of E-selectin and P-selectin rolling at comparable binding strength.

1997 • 91 citations

Differences between human eosinophils and neutrophils in the function and expression of sialic acid-containing counterligands for E-selectin.

1994 • 87 citations

Eosinophil Tethering to Interleukin-4–Activated Endothelial Cells Requires Both P-Selectin and Vascular Cell Adhesion Molecule-1

1998 • 83 citations

Comparison of human eosinophil and neutrophil adhesion to endothelial cells under nonstatic conditions. Role of L-selectin.

1994 • 70 citations

E-selectin preferentially supports neutrophil but not eosinophil rolling under conditions of flow in vitro and in vivo.

1996 • 67 citations

Sialylated O-glycans and L-selectin sequentially mediate myeloid cell rolling in vivo

1995 • 44 citations

Overlapping Roles for L-Selectin and P-Selectin in Antigen-Induced Immune Responses in the Microvasculature

1999 • 35 citations

Antigen-Induced Recruitment of Eosinophils: Importance of CD4+ T Cells, IL5, and Mast Cells

1994 • 23 citations

Contribution of endothelial selectins and alpha 4 integrins to eosinophil trafficking in allergic and nonallergic inflammatory reactions in skin.

1998 • 22 citations

Contribution of Endothelial Selectins and α4 Integrins to Eosinophil Trafficking in Allergic and Nonallergic Inflammatory Reactions in Skin

1998 • 16 citations