An auxiliary mode of apoptotic DNA fragmentation provided by phagocytes

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Mitochondria and Apoptosis

1998 • 8,909 citations

Caspases: Enemies Within

1998 • 6,923 citations

Death Receptors: Signaling and Modulation

1998 • 5,873 citations

Apoptosis by Death Factor

1997 • 5,038 citations

Glucocorticoid-induced thymocyte apoptosis is associated with endogenous endonuclease activation

1980 • 4,591 citations

A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD

1998 • 3,169 citations

The polypeptide encoded by the cDNA for human cell surface antigen Fas can mediate apoptosis

1991 • 2,815 citations

Programmed Cell Death in Animal Development

1997 • 2,690 citations

Lethal effect of the anti-Fas antibody in mice

1993 • 1,915 citations

DFF, a Heterodimeric Protein That Functions Downstream of Caspase-3 to Trigger DNA Fragmentation during Apoptosis

1997 • 1,848 citations

Genetic control of programmed cell death in the nematode C. elegans

1986 • 1,790 citations

Bafilomycins: a class of inhibitors of membrane ATPases from microorganisms, animal cells, and plant cells.

1988 • 1,737 citations

Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis

1998 • 1,651 citations

F4/80, a monoclonal antibody directed specifically against the mouse macrophage

1981 • 1,582 citations

Cell Death in Development

1999 • 1,567 citations

T-cell apoptosis detected in situ during positive and negative selection in the thymus

1994 • 1,071 citations

Cell suicide for beginners

1998 • 686 citations

Nuclear changes in apoptosis

1995 • 538 citations

The 40-kDa subunit of DNA fragmentation factor induces DNA fragmentation and chromatin condensation during apoptosis

1998 • 534 citations

Identification of Deoxyribonuclease II as an Endonuclease Involved in Apoptosis

1993 • 428 citations

DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis.

1995 • 422 citations

Vacuolar ATPase activity is required for endosomal carrier vesicle formation.

1994 • 418 citations

Terminal labeling and addition of homopolymer tracts to duplex DNA fragments by terminal deoxynudeotidyl transferase

1976 • 416 citations

Mutations Affecting Programmed Cell Deaths in the Nematode Caenorhabditis elegans s

1983 • 389 citations

Recognizing death: the phagocytosis of apoptotic cells

1998 • 381 citations

Targeted mutation in the Fas gene causes hyperplasia in peripheral lymphoid organs and liver

1995 • 377 citations

Apoptosis: The importance of being eaten

1998 • 349 citations

Horizontal Transfer of DNA by the Uptake of Apoptotic Bodies

1999 • 318 citations

Death by a thousand cuts: an ever increasing list of caspase substrates

1998 • 286 citations

Isolation and Characterization of the Human Chromosomal Gene for Polypeptide Chain Elongation Factor-1α

1989 • 277 citations

Use of the human elongation factor 1α promoter as a versatile and efficient expression system

1990 • 273 citations

Resistance to DNA fragmentation and chromatin condensation in mice lacking the DNA fragmentation factor 45

1998 • 179 citations

NUC-1, aCaenorhabditis elegansDNase II homolog, functions in an intermediate step of DNA degradation during apoptosis

2000 • 174 citations

Activation of the Apoptotic Endonuclease DFF40 (Caspase-activated DNase or Nuclease)

1999 • 168 citations

Apoptotic nuclear morphological change without DNA fragmentation

1999 • 158 citations

Macrophages induce apoptosis in normal cells in vivo

1997 • 154 citations

α‐Tocopheryl succinate‐induced apoptosis in Jurkat T cells involves caspase‐3 activation, and both lysosomal and mitochondrial destabilisation

1999 • 125 citations

Involvement of caspase 3-activated DNase in internucleosomal DNA cleavage induced by diverse apoptotic stimuli

1999 • 120 citations

Immunogenic DNA-related factors. Nucleosomes spontaneously released from normal murine lymphoid cells stimulate proliferation and immunoglobulin synthesis of normal mouse lymphocytes.

1990 • 112 citations

Functional Differences of Two Forms of the Inhibitor of Caspase-activated DNase, ICAD-L, and ICAD-S

1999 • 94 citations

The Cloning and Expression of Human Deoxyribonuclease II

1998 • 83 citations

Molecular Cloning of the cDNA Encoding Human Deoxyribonuclease II

1998 • 81 citations

Functional Interaction of DFF35 and DFF45 with Caspase-activated DNA Fragmentation Nuclease DFF40

1999 • 80 citations

Horizontal Transfer of DNA by the Uptake of Apoptotic Bodies

1999 • 76 citations

An Ultrastructural and Immunohistochemical Study of PC12 Cells During Apoptosis Induced by Serum Deprivation with Special Reference to Autophagy and Lysosomal Cathepsins.

1998 • 71 citations

Do macrophages kill through apoptosis?

1996 • 69 citations

Molecular cloning and characterization of human and murine DNase II

1998 • 59 citations

Caspase Activation Is an Early Event in Anthracycline-Induced Apoptosis and Allows Detection of Apoptotic Cells before They Are Ingested by Phagocytes

1998 • 53 citations

Inhibition of Apoptosis-Associated DNA Fragmentation Activity in Nonapoptotic Cells: The Role of DNA Fragmentation Factor-45 (DFF45/ICAD)

1998 • 51 citations

Introduction of Human γ1 Immunoglobulin Genes into Fertilized Mouse Eggs1

1984 • 50 citations

Porcine Spleen Deoxyribonuclease II

1998 • 42 citations

A stable cellular marker for the analysis of mouse chimeras: the bacterial chloramphenicol acetyltransferase gene driven by the human elongation factor la promoter

1991 • 35 citations

Structure and promoter analysis of murine CAD and ICAD genes

1999 • 30 citations

Enhancement of TdT-mediated dUTP-biotin nick end-labeling (TUNEL) method using mung bean nuclease, a single-stranded DNA digestion enzyme.

1996 • 23 citations