Expression and localization of cyclo-oxygenase isoforms in non-small cell lung cancer

Signal transduction by receptors with tyrosine kinase activity

1990 • 5,528 citations

Cancer metastasis and angiogenesis: An imbalance of positive and negative regulation

1991 • 2,774 citations

THE CHEMOTACTIC EFFECT OF MIXTURES OF ANTIBODY AND ANTIGEN ON POLYMORPHONUCLEAR LEUCOCYTES

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Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells

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Expression of cyclooxygenase-1 and -2 in human colorectal cancer.

1995 • 1,135 citations

Expression of prostaglandin G/H synthase-1 and -2 protein in human colon cancer.

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A "quickscore" method for immunohistochemical semiquantitation: validation for oestrogen receptor in breast carcinomas.

1995 • 827 citations

Increased expression of cyclooxygenase 2 occurs frequently in human lung cancers, specifically in adenocarcinomas.

1998 • 825 citations

Inhibition of human colon cancer cell growth by selective inhibition of cyclooxygenase-2.

1997 • 734 citations

Cell migration is essential for sustained growth of keratinocyte colonies: The roles of transforming growth factor-α and epidermal growth factor

1987 • 703 citations

Effects of nonsteroidal anti-inflammatory drugs on proliferation and on induction of apoptosis in colon cancer cells by a prostaglandin-independent pathway

1996 • 613 citations

Increased cyclooxygenase-2 levels in carcinogen-induced rat colonic tumors

1996 • 438 citations

Transcription of cyclooxygenase-2 is enhanced in transformed mammary epithelial cells.

1996 • 426 citations

[30] Use and specificity of genistein as inhibitor of protein-tyrosine kinases

1991 • 421 citations

Isolation, culture and characterization of human peritoneal mesothelial cells

1990 • 398 citations

Apoptosis primarily accounts for the growth-inhibitory properties of sulindac metabolites and involves a mechanism that is independent of cyclooxygenase inhibition, cell cycle arrest, and p53 induction.

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Regulation of prostaglandin synthase-1 and prostaglandin synthase-2

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Regulation of the cytoskeleton in mesothelial cells: Reversible loss of keratin and increase in vimentin during rapid growth in culture

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Epidermal Growth Factor-related Peptides Activate Distinct Subsets of ErbB Receptors and Differ in Their Biological Activities

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Expression of adhesion molecules and chemotactic cytokines in cultured human mesothelial cells.

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Receptor tyrosine kinase signaling required for integrin alpha v beta 5-directed cell motility but not adhesion on vitronectin.

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Ligand occupancy of the alpha-V-beta3 integrin is necessary for smooth muscle cells to migrate in response to insulin-like growth factor.

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Epidermal growth factor promotes the chemotactic migration of cultured rat intestinal epithelial cells

1985 • 226 citations

The Roles of Integrins and Extracellular Matrix Proteins in the Insulin-like Growth Factor I-stimulated Chemotaxis of Human Breast Cancer Cells

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Dietary fat and colon cancer: modulation of cyclooxygenase-2 by types and amount of dietary fat during the postinitiation stage of colon carcinogenesis.

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Regulation of cell movement: the motogenic cytokines

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The Epidermal Growth Factor Family

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Yes, but do they still get headaches?

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The molecular biology of mammalian arachidonic acid metabolism

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Cytokine-induced pseudopodial protrusion is coupled to tumour cell migration

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Prostaglandins, their inhibitors and cancer

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Amphiregulin induces tyrosine phosphorylation of the epidermal growth factor receptor and p185erbB2. Evidence that amphiregulin acts exclusively through the epidermal growth factor receptor at the surface of human epithelial cells.

1993 • 138 citations

Establishment of a human in vitro mesothelial cell model system for investigating mechanisms of asbestos-induced mesothelioma.

1989 • 137 citations

Arachidonic Acid Metabolism in Airway Epithelial Cells

1992 • 136 citations

Role of Pleural Mesothelial Cells in the Production of the Submesothelial Connective Tissue Matrix of Lung

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Regulation of prostaglandin endoperoxide synthase (cyclooxygenase) isozyme expression

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Profiles of prostaglandin biosynthesis in normal lung and tumor tissue from lung cancer patients.

1988 • 131 citations

Rectal proliferation and polyp occurrence in patients with familial adenomatous polyposis after sulindac treatment

1994 • 130 citations

Expression and activity of nitric oxide synthases in human airway epithelium.

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Stimulatory effects of fibronectin and EGF on migration of corneal epithelial cells.

1987 • 126 citations

Regulation of the inducible cyclo‐oxygenase pathway in human cultured airway epithelial (A549) cells by nitric oxide

1997 • 118 citations

THE PHYSIOLOGY OF THE SEROUS MEMBRANES

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Immunocytochemical localization of cyclooxygenase-1 and cyclooxygenase-2 in the rat stomach

1995 • 100 citations

New Prognostic Factors in Lung Cancer

1995 • 95 citations

Stimulation of DNA synthesis in cultured primary human mesothelial cells by specific growth factors

1988 • 94 citations

Cyclooxygenase and lipoxygenase inhibitors in cancer therapy

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Chemotaxis and haptotaxis of human malignant mesothelioma cells: effects of fibronectin, laminin, type IV collagen, and an autocrine motility factor-like substance.

1993 • 88 citations

Profiles of prostaglandin biosynthesis in sixteen established cell lines derived from human lung, colon, prostate, and ovarian tumors.

1988 • 80 citations

Human fibroblast-derived growth factor is a mitogen and chemoattractant for endothelial cells

1987 • 78 citations

Evidence for prostanoid biosynthesis as a biochemical feature of certain subclasses of non-small cell carcinomas of the lung as determined in established cell lines derived from human lung tumors

1989 • 75 citations

Bronchial Epithelial Cells Respond to Insulin and Insulin-like Growth Factor-I as a Chemoattractant

1990 • 56 citations

The Molecular Genetics of Lung Cancer

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New functions of epidermal growth factor: Stimulation of capillary endothelial cell migration and matrix dependent proliferation

1985 • 46 citations

Prostaglandin and thromboxane synthesis by Lewis lung carcinoma during growth.

1985 • 38 citations

The epidermal growth factor/transforming growth factor-?? family and their receptors

1995 • 38 citations

Differential responses to growth factors by normal human mesothelial cultures from individual donors

1989 • 36 citations

Association of a functional prostaglandin E2-protein kinase A coupling with responsiveness of metastatic Lewis lung carcinoma variants to prostaglandin E2 and to prostaglandin E2-producing nonmetastatic Lewis lung carcinoma variants.

1990 • 33 citations

Basic epidemiological methods and biostatistics : a practical guidebook

1995 • 33 citations

The EGF-inducible protein EIP-1 of migrating normal and malignant rat liver epithelial cells is identical to plasminogen activator inhibitor 1 and is a component of the ECM migration tracks

1992 • 25 citations

Retinoid-induced differentiation regulates prostaglandin H synthase and cPLA2 expression in tracheal epithelium

1996 • 21 citations

Cyclo-oxygenase and Colon Cancer: Clues to the Aspirin Effect?

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Molecular cloning of a cell-surface glycoprotein that can potentially discriminate mesothelium from epithelium: its identification as vascular cell adhesion molecule 1

1995 • 18 citations

Cloning and Expression of cDNA Encoding Human Betacellulin, a New Member of the EGF Family

1993 • 1 citations