The Effect of Paroxetine on 5-HT_2A Receptors in Depression: An [¹⁸F]Setoperone PET Imaging Study

A RATING SCALE FOR DEPRESSION

1960 • 30,921 citations

Statistical parametric maps in functional imaging: A general linear approach

1994 • 9,606 citations

Spatial registration and normalization of images

1995 • 3,673 citations

A Molecular and Cellular Theory of Depression

1997 • 2,091 citations

Assessing the significance of focal activations using their spatial extent

1994 • 1,917 citations

Long-Term Antidepressant Treatment Decreases Spiroperidol-Labeled Serotonin Receptor Binding

1980 • 840 citations

Automated three‐dimensional registration of magnetic resonance and positron emission tomography brain images by multiresolution optimization of voxel similarity measures

1997 • 676 citations

5-Hydroxytryptamine _2A serotonin receptors in the primate cerebral cortex: Possible site of action of hallucinogenic and antipsychotic drugs in pyramidal cell apical dendrites

1998 • 510 citations

5-HT_2AReceptor-Mediated Regulation of Brain-Derived Neurotrophic Factor mRNA in the Hippocampus and the Neocortex

1997 • 448 citations

The primate serotonergic system: a review of human and animal studies and a report on Macaca fascicularis.

1986 • 289 citations

5-Hydroxytryptamine2-Family Receptors (5-Hydroxytryptamine2A, 5-Hydroxytryptamine2B, 5-Hydroxytryptamine2C) Where Structure Meets Function

1998 • 280 citations

Fluvoxamine preferentially increases extracellular 5-hydroxytryptamine in the raphe nuclei: An in vivo microdialysis study

1992 • 275 citations

Chronic treatment with fluvoxamine increases extracellular serotonin in frontal cortex but not in raphe nuclei

1993 • 239 citations

Electrophysiological investigations on the effect of repeated zimelidine administration on serotonergic neurotransmission in the rat

1983 • 223 citations

Assessment of Spatial Normalization of PET Ligand Images Using Ligand-Specific Templates

1999 • 172 citations

Regional and subcellular localization in human brain of [3H]paroxetine binding, a marker of serotonin uptake sites

1988 • 171 citations

Prefrontal Cortex 5-HT₂ Receptors in Depression: An [¹⁸F]Setoperone PET Imaging Study

1999 • 165 citations

PET Imaging of Serotonin Type 2A Receptors in Late-Life Neuropsychiatric Disorders

1999 • 163 citations

Decrease in Brain Serotonin 2 Receptor Binding in Patients With Major Depression Following Desipramine Treatment

1999 • 151 citations

Effects of conditioned fear stress on 5-HT release in the rat prefrontal cortex

1995 • 149 citations

Primary Structure of the Human Platelet Serotonin 5‐HT_2A Receptor: Identity with Frontal Cortex Serotonin 5‐HT_2A Receptor

1994 • 146 citations

Differential regulation of 5‐hydroxytryptamine release by GABA_A and GABA_B receptors in midbrain raphe nuclei and forebrain of rats

1996 • 144 citations

2,5-Dimethoxy-4-methyl-amphetamine (STP): A New Hallucinogenic Drug

1967 • 143 citations

Chronic fluoxetine treatment upregulates 5‐HT uptake sites and 5‐HT₂ receptors in rat brain: An autoradiographic study

1993 • 142 citations

Characterization and regional distribution of serotonin S2-receptors in human brain

1983 • 136 citations

Autoradiographic localization of D1 and D2 dopamine receptors in the human brain

1988 • 124 citations

A Method for the In Vivo Investigation of the Serotonergic 5‐HT₂ Receptors in the Human Cerebral Cortex Using Positron Emission Tomography and ¹⁸F‐Labeled Setoperone

1990 • 110 citations

Platelet serotonergic indices in major depression: up-regulation of 5-HT2A receptors unchanged by antidepressant treatment

1997 • 108 citations

Rapid desensitization and down-regulation of 5-HT2 receptors by DOM treatment

1989 • 102 citations

Frontal 5-HT 2A receptors studied in depressive patients during chronic treatment by selective serotonin reuptake inhibitors

1997 • 100 citations

Serotonin 5-HT₂ Receptors in Schizophrenia: A PET Study Using [¹⁸F]Setoperone in Neuroleptic-Naive Patients and Normal Subjects

1999 • 100 citations

Autoradiographic analysis of [3H]ketanserin binding in the human brain postmortem: effect of suicide

1990 • 95 citations

[18F]Setoperone: A new high-affinity ligand for positron emission tomography study of the serotonin-2 receptors in baboon brain in vivo

1988 • 95 citations

Receptor alterations associated with serotonergic agents: an autoradiographic analysis.

1987 • 87 citations

Effect of aging in human cortical pre- and postsynaptic serotonin binding sites

1993 • 85 citations

Age-related alteration of PKC, a key enzyme in memory processes

1998 • 76 citations

DOM (STP), a New Hallucinogenic Drug, and DOET: Effects in Normal Subjects

1968 • 74 citations

5‐HT₂ Receptors, Roles and Regulation

1990 • 63 citations

Both systemic and local administration of benzodiazepine agonists inhibit the in vivo release of 5-HT from ventral hippocampus

1989 • 62 citations

Positron emission tomographic analysis of central 5-hydroxytryptamine2 receptor occupancy in healthy volunteers treated with the novel antipsychotic agent, ziprasidone.

1996 • 57 citations

An hallucinogenic amphetamine analog (DOM) in man

1969 • 55 citations

Manipulations of synaptic serotonin: Discrepancy of effects on serotonin S1 and S2 sites

1983 • 47 citations

Distribution and characterization of [3H]mesulergine binding in human brain postmortem

1999 • 46 citations

Characterisation of Human 5‐Hydroxytryptamine_2A and 5‐Hydroxytryptamine_2C Receptors Expressed in the Human Neuroblastoma Cell Line SH‐SY5Y: Comparative Stimulation by Hallucinogenic Drugs

1996 • 45 citations

The effects of single dose nefazodone and paroxetine upon 5-HT 2A binding potential in humans using [ 18 F]-setoperone PET

1999 • 45 citations

Estimation of neocortical serotonin-2 receptor binding potential by single-dose fluorine-18-setoperone kinetic PET data analysis.

1996 • 38 citations

Interactions between Effectors Linked to Serotonin Receptors

1998 • 33 citations

Synthesis, affinity and specificity of 18F-setoperone, a potential ligand for in-vivo imaging of cortical serotonin receptors

1988 • 33 citations

Reliability of a simple non-invasive method for the evaluation of 5-HT2 receptors using [18F]-setoperone PET imaging

1997 • 30 citations

Blood–Cerebrospinal Fluid and Blood‐Brain Barriers Imaged by ¹⁸F‐Labeled Metabolites of ¹⁸F‐Setoperone Studied in Humans Using Positron Emission Tomography

1992 • 19 citations

AN IMPROVED METHOD FOR THE MEASUREMENT OF PAROXETINE IN HUMAN SERUM/PLASMA BY HPLC WITH FLUORESCENCE DETECTION.

1999 • 4 citations

Deleted Work

1955 • 0 citations