Back to search

Cyclooxygenase-2 is up-regulated in proliferative inflammatory atrophy of the prostate, but not in prostate carcinoma.

Data up to Jan 2025

Published2001
Citations267
References48

Total Citations Per Year

Abstract

References (48)

Tissue microarrays for high-throughput molecular profiling of tumor specimens

1998 • 4,104 citations

Cyclooxygenases: Structural, Cellular, and Molecular Biology

2000 • 2,837 citations

Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)

1996 • 2,387 citations

Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2

1995 • 2,308 citations

Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells

1998 • 2,282 citations

PPARδ Is an APC-Regulated Target of Nonsteroidal Anti-Inflammatory Drugs

1999 • 1,091 citations

Proliferative Inflammatory Atrophy of the Prostate

1999 • 868 citations

Role ofBAXin the Apoptotic Response to Anticancer Agents

2000 • 854 citations

Important Advances in Oncology

1991 • 768 citations

Inflammation and cancer: role of phagocyte-generated oxidants in carcinogenesis

1990 • 741 citations

Expression of cyclooxygenase-2 in human lung carcinoma.

1998 • 729 citations

The Cyclooxygenase-2 Inhibitor Celecoxib Induces Apoptosis by Blocking Akt Activation in Human Prostate Cancer Cells Independently of Bcl-2

2000 • 670 citations

Expression of Cyclooxygenase-1 and Cyclooxygenase-2 in Human Breast Cancer

1998 • 665 citations

Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis

1998 • 593 citations

Over-expression of cyclooxygenase-2 in human prostate adenocarcinoma

2000 • 535 citations

NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells.

1998 • 439 citations

Molecular pathology of cyclooxygenase-2 in neoplasia.

2000 • 406 citations

INHIBITION OF CYCLOOXYGENASE-2 SUPPRESSES ANGIOGENESIS AND THE GROWTH OF PROSTATE CANCER IN VIVO

2000 • 361 citations

Expression of cyclooxygenase-2 in prostate carcinoma

2000 • 319 citations

Mutagenesis and carcinogenesis: Endogenous and exogenous factors

1989 • 266 citations

Morphologic transitions between proliferative inflammatory atrophy and high-grade prostatic intraepithelial neoplasia

2000 • 249 citations

Localization of Cyclooxygenase-2 in Human Sporadic Colorectal Adenomas

2000 • 222 citations

Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines

1999 • 211 citations

Atrophy and hyperplasia in the prostate proper

1954 • 204 citations

Cytoplasmic induction and over‐expression of cyclooxygenase‐2 in human prostate cancer: implications for prevention and treatment

2000 • 177 citations

Inverse association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs): results of a case-control study.

2000 • 166 citations

Increased expression of cyclooxygenase-2 and nitric oxide synthase-2 in human prostate cancer

2001 • 151 citations

Postatrophic Hyperplasia of the Prostate Gland

2001 • 143 citations

Histology and Cellular Kinetics of Prostatic Atrophy

1998 • 142 citations

Cyclooxygenase-2 expression is up-regulated in transitional cell carcinoma and its preneoplastic lesions in the human urinary bladder.

2000 • 138 citations

New insights into the role of COX 2 in inflammation

2000 • 130 citations

Growth inhibition and induction of apoptosis in colorectal tumor cells by cyclooxygenase inhibitors

2001 • 128 citations

Prostaglandin-H-synthase isozyme expression in normal and neoplastic human skin

1999 • 119 citations

Relational Database Structure to Manage High-Density Tissue Microarray Data and Images for Pathology Studies Focusing on Clinical Outcome

2001 • 113 citations

Decreased concentrations of prostate-specific antigen and human glandular kallikrein 2 in malignant versus nonmalignant prostatic tissue

2000 • 109 citations

Alterations in Lipoxygenase and Cyclooxygenase-2 Catalytic Activity and mRNA Expression in Prostate Carcinoma

2001 • 108 citations

GSTA1 expression in normal, preneoplastic, and neoplastic human prostate tissue

2001 • 108 citations

ATROPHY AND REGENERATION IN THE PATHOGENESIS OF PROSTATIC CARCINOMA

1968 • 93 citations

Evaluation of PAP and PSA gene expression in prostatic hyperplasia and prostatic carcinoma using northern‐blot analyses, in situ hybridization and immunohistochemical stainings with monoclonal and bispecific antibodies

1993 • 82 citations

Immunohistochemical Localization of Cyclooxygenase-1 and Cyclooxygenase-2 in the Human Fetal and Adult Male Reproductive Tracts1

2000 • 70 citations

Rapid microwave-stimulated fixation of entire prostatectomy specimens

1997 • 69 citations

8p22> loss concurrent with 8c gain is associated with poor outcome in prostate cancer

2000 • 69 citations

DNA Oxidation Induced by Cyclooxygenase-2

2001 • 61 citations

Blocking the endogenous formation of N-nitroso compounds and related carcinogens.

1996 • 57 citations

Immunohistochemical study of cyclooxygenases in prostatic adenocarcinoma; relationship to apoptosis and Bcl-2 protein expression.

2000 • 55 citations

Aspirin and other nonsteroidal anti-inflammatory agents in the prevention of colorectal cancer.

1996 • 39 citations

Accessory Sex Gland Function in Normal Young (20–25 Years) and Middle‐aged (50–55 Years) Men

1986 • 29 citations

PROSTATE PATHOLOGY

2001 • 12 citations

Cited By (0)

Loading...
Cyclooxygenase-2 is up-regulated in proliferative inflammatory atrophy of the prostate,… (2001) – PubMed | Metascience Observatory Explorer