Cyclooxygenase-2 is up-regulated in proliferative inflammatory atrophy of the prostate, but not in prostate carcinoma.
Data up to Jan 2025
Total Citations Per Year
Abstract
References (48)
Tissue microarrays for high-throughput molecular profiling of tumor specimens
1998 • 4,104 citations
Cyclooxygenases: Structural, Cellular, and Molecular Biology
2000 • 2,837 citations
Suppression of Intestinal Polyposis in ApcΔ716 Knockout Mice by Inhibition of Cyclooxygenase 2 (COX-2)
1996 • 2,387 citations
Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
1995 • 2,308 citations
Cyclooxygenase Regulates Angiogenesis Induced by Colon Cancer Cells
1998 • 2,282 citations
PPARδ Is an APC-Regulated Target of Nonsteroidal Anti-Inflammatory Drugs
1999 • 1,091 citations
Proliferative Inflammatory Atrophy of the Prostate
1999 • 868 citations
Role ofBAXin the Apoptotic Response to Anticancer Agents
2000 • 854 citations
Important Advances in Oncology
1991 • 768 citations
Inflammation and cancer: role of phagocyte-generated oxidants in carcinogenesis
1990 • 741 citations
Expression of cyclooxygenase-2 in human lung carcinoma.
1998 • 729 citations
The Cyclooxygenase-2 Inhibitor Celecoxib Induces Apoptosis by Blocking Akt Activation in Human Prostate Cancer Cells Independently of Bcl-2
2000 • 670 citations
Expression of Cyclooxygenase-1 and Cyclooxygenase-2 in Human Breast Cancer
1998 • 665 citations
Mechanisms underlying nonsteroidal antiinflammatory drug-mediated apoptosis
1998 • 593 citations
Over-expression of cyclooxygenase-2 in human prostate adenocarcinoma
2000 • 535 citations
NS398, a selective cyclooxygenase-2 inhibitor, induces apoptosis and down-regulates bcl-2 expression in LNCaP cells.
1998 • 439 citations
Molecular pathology of cyclooxygenase-2 in neoplasia.
2000 • 406 citations
INHIBITION OF CYCLOOXYGENASE-2 SUPPRESSES ANGIOGENESIS AND THE GROWTH OF PROSTATE CANCER IN VIVO
2000 • 361 citations
Expression of cyclooxygenase-2 in prostate carcinoma
2000 • 319 citations
Mutagenesis and carcinogenesis: Endogenous and exogenous factors
1989 • 266 citations
Morphologic transitions between proliferative inflammatory atrophy and high-grade prostatic intraepithelial neoplasia
2000 • 249 citations
Localization of Cyclooxygenase-2 in Human Sporadic Colorectal Adenomas
2000 • 222 citations
Sulindac derivatives inhibit growth and induce apoptosis in human prostate cancer cell lines
1999 • 211 citations
Atrophy and hyperplasia in the prostate proper
1954 • 204 citations
Cytoplasmic induction and over‐expression of cyclooxygenase‐2 in human prostate cancer: implications for prevention and treatment
2000 • 177 citations
Inverse association of prostate cancer and non-steroidal anti-inflammatory drugs (NSAIDs): results of a case-control study.
2000 • 166 citations
Increased expression of cyclooxygenase-2 and nitric oxide synthase-2 in human prostate cancer
2001 • 151 citations
Postatrophic Hyperplasia of the Prostate Gland
2001 • 143 citations
Histology and Cellular Kinetics of Prostatic Atrophy
1998 • 142 citations
Cyclooxygenase-2 expression is up-regulated in transitional cell carcinoma and its preneoplastic lesions in the human urinary bladder.
2000 • 138 citations
New insights into the role of COX 2 in inflammation
2000 • 130 citations
Growth inhibition and induction of apoptosis in colorectal tumor cells by cyclooxygenase inhibitors
2001 • 128 citations
Prostaglandin-H-synthase isozyme expression in normal and neoplastic human skin
1999 • 119 citations
Relational Database Structure to Manage High-Density Tissue Microarray Data and Images for Pathology Studies Focusing on Clinical Outcome
2001 • 113 citations
Decreased concentrations of prostate-specific antigen and human glandular kallikrein 2 in malignant versus nonmalignant prostatic tissue
2000 • 109 citations
Alterations in Lipoxygenase and Cyclooxygenase-2 Catalytic Activity and mRNA Expression in Prostate Carcinoma
2001 • 108 citations
GSTA1 expression in normal, preneoplastic, and neoplastic human prostate tissue
2001 • 108 citations
ATROPHY AND REGENERATION IN THE PATHOGENESIS OF PROSTATIC CARCINOMA
1968 • 93 citations
Evaluation of PAP and PSA gene expression in prostatic hyperplasia and prostatic carcinoma using northern‐blot analyses, in situ hybridization and immunohistochemical stainings with monoclonal and bispecific antibodies
1993 • 82 citations
Immunohistochemical Localization of Cyclooxygenase-1 and Cyclooxygenase-2 in the Human Fetal and Adult Male Reproductive Tracts1
2000 • 70 citations
Rapid microwave-stimulated fixation of entire prostatectomy specimens
1997 • 69 citations
8p22> loss concurrent with 8c gain is associated with poor outcome in prostate cancer
2000 • 69 citations
DNA Oxidation Induced by Cyclooxygenase-2
2001 • 61 citations
Blocking the endogenous formation of N-nitroso compounds and related carcinogens.
1996 • 57 citations
Immunohistochemical study of cyclooxygenases in prostatic adenocarcinoma; relationship to apoptosis and Bcl-2 protein expression.
2000 • 55 citations
Aspirin and other nonsteroidal anti-inflammatory agents in the prevention of colorectal cancer.
1996 • 39 citations
Accessory Sex Gland Function in Normal Young (20–25 Years) and Middle‐aged (50–55 Years) Men
1986 • 29 citations
PROSTATE PATHOLOGY
2001 • 12 citations