5.2 Receptor diversity of human T-cell receptor ?? expressing cells

T-cell antigen receptor genes and T-cell recognition

1988 • 3,099 citations

Polymerase Chain Reaction with Single-Sided Specificity: Analysis of T Cell Receptor δ Chain

1989 • 640 citations

Junctional sequences of T cell receptor γδ genes: Implications for γδ T cell lineages and for a novel intermediate of V-(D)-J joining

1989 • 572 citations

Evidence for extrathymic changes in the T cell receptor gamma/delta repertoire.

1990 • 510 citations

The Structure, Function, and Molecular Genetics of the gamma/delta T Cell Receptor

1989 • 476 citations

Organization and sequences of the diversity, joining, and constant region genes of the human T-cell receptor beta chain.

1985 • 416 citations

Diversity and structure of human T-cell receptor alpha-chain variable region genes.

1987 • 274 citations

Sequences and repertoire of the human T cell receptor α and β chain variable region genes in thymocytes

1987 • 226 citations

Distribution of T cells bearing different forms of the T cell receptor gamma/delta in normal and pathological human tissues.

1989 • 215 citations

Analysis of immunoglobulin and T cell receptor genes. Part I: Basic and technical aspects

1991 • 214 citations

Organization and sequences of the variable, joining and constant region genes of the human T-cell receptor α-chain

1985 • 201 citations

Two subsets of human T lymphocytes expressing gamma/delta antigen receptor are identifiable by monoclonal antibodies directed to two distinct molecular forms of the receptor.

1988 • 183 citations

Molecular analysis of human gamma/delta+ clones from thymus and peripheral blood.

1989 • 177 citations

Subpopulations of human peripheral T gamma delta lymphocytes

1989 • 170 citations

Distinct molecular forms of human T cell receptor gamma/delta detected on viable T cells by a monoclonal antibody.

1988 • 161 citations

Sequence and organization of the diversity, joining, and constant region genes of the human T-cell delta-chain locus.

1988 • 153 citations

A distinct wave of human T cell receptor gamma/delta lymphocytes in the early fetal thymus: evidence for controlled gene rearrangement and cytokine production.

1990 • 148 citations

Diversity and structure of human T cell receptor delta chain genes in peripheral blood gamma/delta-bearing T lymphocytes.

1989 • 137 citations

Genetic polymorphism and exon changes of the constant regions of the human T-cell rearranging gene gamma.

1986 • 136 citations

Human T-cell-receptor delta chain: genomic organization, diversity, and expression in populations of cells.

1988 • 136 citations

A unique V-J-C-rearranged gene encodes a gamma protein expressed on the majority of CD3+ T cell receptor-alpha/beta- circulating lymphocytes.

1988 • 133 citations

Sequences and repertoire of human T cell receptor alpha chain variable region genes in mature T lymphocytes.

1986 • 132 citations

Use of oligonucleotide probes directed against T cell antigen receptor gamma delta variable-(diversity)-joining junctional sequences as a general method for detecting minimal residual disease in acute lymphoblastic leukemias.

1990 • 130 citations

The expression of T cell receptor-associated proteins during T cell ontogeny in man.

1989 • 122 citations

A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31- lymphocytes to express their functional program(s).

1988 • 116 citations

Human T cell gamma chain joining regions and T cell development.

1987 • 114 citations

Diversity and structure of human T-cell receptor beta-chain variable region genes.

1986 • 112 citations

Diversity and organization of human T cell receptor delta variable gene segments.

1989 • 107 citations

Complex rearrangements within the human J delta-C delta/J alpha-C alpha locus and aberrant recombination between J alpha segments.

1988 • 105 citations

Characterization of an expressed CDS-associated Ti γ-chain reveals Cγ domain polymorphism

1987 • 101 citations

Extensive Junctional Diversity of Rearranged Human T Cell Receptor δ Genes

1988 • 95 citations

Signal transduction of gamma/delta T cell antigen receptor with a novel mitogenic anti-delta antibody.

1988 • 93 citations

Diversity in junctional sequences associated with the common human V gamma 9 and V delta 2 gene segments in normal blood and lung compared with the limited diversity in a granulomatous disease.

1990 • 90 citations

Human T-cell γ genes contain N segments and have marked junctional variability

1986 • 87 citations

Non‐random expression of T cell receptor γ and δ variable gene segments in functional T lymphocyte clones from human peripheral blood

1989 • 86 citations

Structurally Divergent Human T Cell Receptor γ Proteins Encoded by Distinct Cγ Genes

1987 • 84 citations

Regulated expression and structure of T cell receptor gamma/delta transcripts in human thymic ontogeny.

1991 • 82 citations

Development of human T lymphocytes and their thymus-dependency.

1990 • 70 citations

Rearrangements of the T cell receptor delta gene in T acute lymphoblastic leukemia cells are distinct from those occurring in B lineage acute lymphoblastic leukemia and preferentially involve one V delta gene segment.

1989 • 57 citations

Analysis of junctional diversity in the preferential V delta 1-J delta 1 rearrangement of fresh T-acute lymphoblastic leukemia cells by in vitro gene amplification and direct sequencing

1989 • 50 citations

Two types of gamma T cell receptors expressed by T cell acute lymphoblastic leukemias

1987 • 40 citations

Diversity, Development, Ligands and Probable Functions of γδ T Cells

1989 • 31 citations

Study of the CD3-associated T-cell receptors reveals further differences between T-cell acute lymphoblastic lymphoma and leukemia

1990 • 30 citations

γδ T-cell receptor repertoire in human peripheral blood and thymus

1990 • 19 citations

The human T-cell rearranging gamma (TRG) genes and the gamma T-cell receptors

1988 • 18 citations

Limited combinatorial repertoire of gamma delta T-cell receptors expressed by T-cell acute lymphoblastic leukemias.

1991 • 16 citations

Analysis of early fetal T-cell receptor δ chain in humans

1990 • 11 citations