Bystander Effect in Lymphoma Cells Vicinal to Irradiated Neoplastic Epithelial Cells: Nitric Oxide Is Involved

Nitric oxide as a secretory product of mammalian cells

1992 • 4,437 citations

Induction of sister chromatid exchanges by extremely low doses of alpha-particles.

1992 • 979 citations

Medium from irradiated human epithelial cells but not human fibroblasts reduces the clonogenic survival of unirradiated cells

1997 • 592 citations

Direct evidence for the participation of gap junction-mediated intercellular communication in the transmission of damage signals from alpha -particle irradiated to nonirradiated cells

2001 • 586 citations

Antagonistic action of imidazolineoxyl N-oxides against endothelium-derived relaxing factor/.bul.NO (nitric oxide) through a radical reaction

1993 • 569 citations

Nitric Oxide: Cytotoxicity versus Cytoprotection— How, Why, When, and Where?

1997 • 510 citations

Intercellular Communication Is Involved in the Bystander Regulation of Gene Expression in Human Cells Exposed to Very Low Fluences of Alpha Particles

1998 • 509 citations

Measurement of nitrate and nitrite in biological samples using nitrate reductase and Griess reaction

1996 • 501 citations

Induction of a bystander mutagenic effect of alpha particles in mammalian cells

2000 • 473 citations

Alpha particles initiate biological production of superoxide anions and hydrogen peroxide in human cells.

1997 • 445 citations

Nitric oxide and cell death

1999 • 443 citations

DNA Damage Induced by Peroxynitrite: Subsequent Biological Effects

1997 • 433 citations

Inactivation of Aerobic and Hypoxic Cells from Three Different Cell Lines by Accelerated³He-,¹²C- and²⁰Ne-Ion Beams

2000 • 424 citations

Studies of bystander effects in human fibroblasts using a charged particle microbeam

1998 • 410 citations

Mechanisms of TGF-β-mediated apoptosis

2002 • 397 citations

Factors underlying the cell growth-related bystander responses to alpha particles.

2000 • 346 citations

The Molecular Theory of Radiation Biology

1981 • 248 citations

Nitric oxide-mediated signaling in the bystander response of individually targeted glioma cells.

2003 • 238 citations

Direct evidence for a bystander effect of ionizing radiation in primary human fibroblasts

2001 • 222 citations

Delayed expression of lethal mutations and genomic instability in the progeny of human epithelial cells that survived in a bystander-killing environment

1997 • 166 citations

Inducible nitric oxide synthase-derived nitric oxide in gene regulation, cell death and cell survival

2001 • 162 citations

Nitric oxide-mediated bystander effect induced by heavy-ions in human salivary gland tumour cells

2002 • 161 citations

Free Radical-Initiated and Gap Junction-Mediated Bystander Effect due to Nonuniform Distribution of Incorporated Radioactivity in a Three-Dimensional Tissue Culture Model

2001 • 153 citations

Regulation of transforming growth factor beta1 by nitric oxide.

1999 • 142 citations

Bystander effect induced by counted high‐LET particles in confluent human fibroblasts: a mechanistic study

2003 • 142 citations

Low-Dose Studies of Bystander Cell Killing with Targeted Soft X Rays

2003 • 141 citations

Activation of Constitutive Nitric-oxide Synthase Activity Is an Early Signaling Event Induced by Ionizing Radiation

2002 • 133 citations

Evidence for Pronounced Bystander Effects Caused by Nonuniform Distributions of Radioactivity using a Novel Three-Dimensional Tissue Culture Model

1999 • 126 citations

Role of Gap Junctional Intercellular Communication in Radiation-Induced Bystander Effects in Human Fibroblasts

2003 • 114 citations

Induction of radioresistance to accelerated carbon-ion beams in recipient cells by nitric oxide excreted from irradiated donor cells of human glioblastoma

2000 • 78 citations

Medium-mediated Bystander Effects on HSG Cells Co-cultivated with Cells Irradiated by X-rays or a 290 MeV/u Carbon Beam

2001 • 68 citations

Gap Junction Intercellular Communication Mediates the Competitive Cell Proliferation Disadvantage of Irradiated Mouse Preimplantation Embryos in Aggregation Chimeras

1999 • 44 citations

Studies about Space Radiation Promote New Fields in Radiation Biology

2002 • 28 citations

Induction of micronuclei in human cell lines and primary cells by combination treatment with gamma-radiation and ethyl methanesulfonate

2002 • 18 citations

A novel method for detecting apoptosis shows that hepatocytes undergo a time dependent increase in DNA cleavage and chromatin condensation which is augmented after TGF-?1 treatment

1996 • 17 citations

Effect of a Hypoxic Cell Sensitizer Doranidazole on the Radiation-induced Apoptosis of Mouse L5178Y Lymphoma Cells

2002 • 15 citations

Sper/NO-induced reversible proliferation inhibition and cycle arrests associated with a micronucleus induction in HSG cells

2003 • 10 citations

Evaluation of the chemosensitivity of head and neck cancer cells based on the diverse function of mutated-p53

2003 • 8 citations

A novel method for detecting apoptosis shows that hepatocytes undergo a time dependent increase in DNA cleavage and chromatin condensation which is augmented after TGF‐β1 treatment

1996 • 1 citations