High-Density Lipoprotein Stimulates Endothelial Cell Migration and Survival Through Sphingosine 1-Phosphate and Its Receptors

Vascular Endothelial Cell Adherens Junction Assembly and Morphogenesis Induced by Sphingosine-1-Phosphate

1999 • 999 citations

p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells

1997 • 847 citations

Sphingosine 1-phosphate promotes endothelial cell barrier integrity by Edg-dependent cytoskeletal rearrangement

2001 • 830 citations

High-density lipoprotein binding to scavenger receptor-BI activates endothelial nitric oxide synthase

2001 • 712 citations

Lysophosphatidic acid mediates the rapid activation of platelets and endothelial cells by mildly oxidized low density lipoprotein and accumulates in human atherosclerotic lesions

1999 • 411 citations

Interaction of sphingosine 1-phosphate with plasma components, including lipoproteins, regulates the lipid receptor-mediated actions

2000 • 393 citations

Suppression of Endothelial Cell Apoptosis by High Density Lipoproteins (HDL) and HDL-associated Lysosphingolipids

2001 • 351 citations

[3] Comparative analysis of mammalian plasma lipoproteins

1986 • 318 citations

Akt-Mediated Phosphorylation of the G Protein-Coupled Receptor EDG-1 Is Required for Endothelial Cell Chemotaxis

2001 • 284 citations

Sphingosine 1-Phosphate-induced Endothelial Cell Migration Requires the Expression of EDG-1 and EDG-3 Receptors and Rho-dependent Activation of αvβ3- and β1-containing Integrins

2001 • 284 citations

Sphingosine 1-Phosphate Activates Akt, Nitric Oxide Production, and Chemotaxis through a GiProtein/Phosphoinositide 3-Kinase Pathway in Endothelial Cells

2001 • 268 citations

Sphingosine 1-Phosphate May Be a Major Component of Plasma Lipoproteins Responsible for the Cytoprotective Actions in Human Umbilical Vein Endothelial Cells

2001 • 265 citations

Sphingosine 1-Phosphate and Activation of Endothelial Nitric-oxide Synthase

2001 • 241 citations

Sphingosine 1-phosphate stimulates proliferation and migration of human endothelial cells possibly through the lipid receptors, Edg-1 and Edg-3

2000 • 231 citations

Plasma lipoproteins behave as carriers of extracellular sphingosine 1-phosphate: is this an atherogenic mediator or an anti-atherogenic mediator?

2002 • 228 citations

Sphingosine-1-Phosphate, a Platelet-Derived Lysophospholipid Mediator, Negatively Regulates Cellular Rac Activity and Cell Migration in Vascular Smooth Muscle Cells

2002 • 219 citations

High-Density Lipoproteins and Endothelial Function

2001 • 208 citations

Sphingosine 1-Phosphate Protects Human Umbilical Vein Endothelial Cells from Serum-deprived Apoptosis by Nitric Oxide Production

2001 • 201 citations

The antiatherogenic role of high-density lipoprotein cholesterol

1998 • 167 citations

Differential Regulation of Sphingosine-1-Phosphate- and VEGF-Induced Endothelial Cell Chemotaxis

2001 • 144 citations

Novel Mechanism for Gonadotropin-Releasing Hormone Neuronal Migration Involving Gas6/Ark Signaling to p38 Mitogen-Activated Protein Kinase

2002 • 126 citations

Involvement of Endothelial Nitric Oxide in Sphingosine-1-Phosphate–Induced Angiogenesis

2002 • 121 citations

Role of lysophosphatidylcholine in the inhibition of endothelial cell motility by oxidized low density lipoprotein.

1996 • 109 citations

Ras/Rac-Dependent Activation of p38 Mitogen-Activated Protein Kinases in Smooth Muscle Cells Stimulated by Cyclic Strain Stress

2000 • 108 citations

Possible role of protein phosphorylation in the mitogenic effect of high density lipoproteins on cultured vascular endothelial cells.

1986 • 85 citations

Sensitized Mast Cells Migrate Toward the Agen: A Response Regulated by p38 Mitogen-Activated Protein Kinase and Rho-Associated Coiled-Coil-Forming Protein Kinase

2001 • 67 citations

Cellular and physiological roles of SR-BI, a lipoprotein receptor which mediates selective lipid uptake

2000 • 66 citations

Activation of Phosphatidylinositol-Specific Phospholipase C by HDL-Associated Lysosphingolipid. Involvement in Mitogenesis but Not in Cholesterol Efflux

2000 • 62 citations

High-density lipoprotein stimulates endothelial cell movement by a mechanism distinct from basic fibroblast growth factor.

1994 • 61 citations

Sphingosine 1-phosphate signaling in atherosclerosis and vascular biology

2002 • 49 citations

A Progress Report

2000 • 21 citations