Meningeal and Perivascular Macrophages of the Central Nervous System Play a Protective Role During Bacterial Meningitis

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

Liposome mediated depletion of macrophages: mechanism of action, preparation of liposomes and applications

1994 • 1,752 citations

Infections of the Central Nervous System

1991 • 603 citations

Histochemical Comparison of Naphthol AS-Phosphates for the Demonstration of Phosphatases

1958 • 541 citations

Bacterial Meningitis: Pathogenesis, Pathophysiology, and Progress

1992 • 488 citations

Identification of monoclonal antibodies reactive with the rat homolog of ICAM-1, and evidence for a differential involvement of ICAM-1 in the adherence of resting versus activated lymphocytes to high endothelial cells

1990 • 293 citations

Identity of ED2‐positive perivascular cells in rat brain

1989 • 281 citations

Intravenous lipopolysaccharide induces cyclooxygenase 2-like immunoreactivity in rat brain perivascular microglia and meningeal macrophages

1997 • 279 citations

Reactive oxygen intermediates contribute to necrotic and apoptotic neuronal injury in an infant rat model of bacterial meningitis due to group B streptococci.

1996 • 235 citations

The role of macrophages, perivascular cells, and microglial cells in the pathogenesis of experimental autoimmune encephalomyelitis

1995 • 213 citations

Involvement of specific macrophage-lineage cells surrounding arterioles in barrier and scavenger function in brain cortex.

1996 • 178 citations

Roles of proinflammatory and anti-inflammatory cytokines in pathophysiology of bacterial meningitis and effect of adjunctive therapy

1996 • 145 citations

Neutralization of Macrophage Inflammatory Protein 2 (MIP-2) and MIP-1α Attenuates Neutrophil Recruitment in the Central Nervous System during Experimental Bacterial Meningitis

1999 • 139 citations

Macrophage Inflammatory Protein-2 Is a Mediator of Polymorphonuclear Neutrophil Influx in Ocular Bacterial Infection

2000 • 138 citations

Liposome targeting to mouse brain: Mannose as a recognition marker

1988 • 137 citations

Cerebral endothelial cells release TNF-alpha after stimulation with cell walls of Streptococcus pneumoniae and regulate inducible nitric oxide synthase and ICAM-1 expression via autocrine loops.

1999 • 126 citations

A method for the selective depletion of perivascular and meningeal macrophages in the central nervous system

2001 • 113 citations

Oxidative Stress in Bacterial Meningitis

1999 • 109 citations

Determinants of focal and segmental glomerulosclerosis in the rat after renal ablation. Evidence for involvement of macrophages and lipids.

1991 • 108 citations

Cerebral Endothelial Cells Release TNF-α After Stimulation with Cell Walls of Streptococcus pneumoniae and Regulate Inducible Nitric Oxide Synthase and ICAM-1 Expression Via Autocrine Loops

1999 • 106 citations

Experimental Listeria meningoencephalitis. Macrophage inflammatory protein-1 alpha and -2 are produced intrathecally and mediate chemotactic activity in cerebrospinal fluid of infected mice.

1995 • 99 citations

Role of Peroxynitrite as a Mediator of Pathophysiological Alterations in Experimental Pneumococcal Meningitis

1999 • 80 citations

Bacterial meningitis in children and adults

1998 • 75 citations

Vcam-1 is a cs1 peptide-inhibitable adhesion molecule expressed by lymph node high endothelium

1993 • 71 citations

Post-formation fluorescent labelling of liposomal membranes

1992 • 62 citations

Monoclonal antibodies against rat macrophages

1994 • 56 citations

PECAM-1 (CD31) expression in the central nervous system and its role in experimental allergic encephalomyelitis in the rat

1996 • 56 citations

Rat Neutrophils Express α4 and β1 Integrins and Bind to Vascular Cell Adhesion Molecule-1 (VCAM-1) and Mucosal Addressin Cell Adhesion Molecule-1 (MAdCAM-1)

1998 • 54 citations

Inhibition of nitric oxide synthase partially attenuates alterations in the blood-cerebrospinal fluid barrier during experimental meningitis in the rat

1995 • 44 citations

Pneumococci Stimulate the Production of the Inducible Nitric Oxide Synthase and Nitric Oxide by Murine Macrophages

1998 • 35 citations

Superoxide production by primary rat cerebral endothelial cells in response to pneumococci

1999 • 34 citations

The Cerebral Perivascular Cells

1998 • 32 citations

Introduction

1998 • 25 citations

Reduction of meningeal macrophages does not decrease migration of granulocytes into the CSF and brain parenchyma in experimental pneumococcal meningitis

1999 • 19 citations

ED2-positive perivascular phagocytes produce interleukin-1? during delayed neuronal loss in the facial nucleus of the rat

1998 • 13 citations

Immunodetection of recombinant proteins based on antibodies directed against a metal binding peptide engineered for purification by immobilized metal affinity chromatography

1992 • 12 citations

Rat Neutrophils Express α4 and β1 Integrins and Bind to Vascular Cell Adhesion Molecule-1 (VCAM-1) and Mucosal Addressin Cell Adhesion Molecule-1 (MAdCAM-1)

1998 • 6 citations