Regulation of the Replication of the Murine Immunoglobulin Heavy Chain Gene Locus: Evaluation of the Role of the 3′ Regulatory Region

A deletion of the human beta-globin locus activation region causes a major alteration in chromatin structure and replication across the entire beta-globin locus.

1990 • 477 citations

Protein-DNA interactions at a yeast replication origin

1992 • 380 citations

Locus Control Region Function and Heterochromatin-Induced Position Effect Variegation

1996 • 373 citations

DNA replication in eukaryotic cells

1997 • 346 citations

Replication structure of the human & beta;-globin gene domain

1993 • 277 citations

A class switch control region at the 3′ end of the immunoglobulin heavy chain locus

1994 • 267 citations

Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells.

1994 • 258 citations

Replication program of active and inactive multigene families in mammalian cells.

1988 • 247 citations

Initiation and termination of DNA replication in human rRNA genes.

1993 • 247 citations

Gamma delta beta-thalassemia due to a de novo mutation deleting the 5' beta-globin gene activation-region hypersensitive sites.

1989 • 240 citations

Once and only once upon a time: specifying and regulating origins of DNA replication in eukaryotic cells.

1996 • 240 citations

A second B cell-specific enhancer 3' of the immunoglobulin heavy-chain locus

1990 • 220 citations

Participation of the Human β-Globin Locus Control Region in Initiation of DNA Replication

1995 • 217 citations

ORC- and Cdc6-dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae.

1996 • 166 citations

Position-dependent variegation of globin transgene expression in mice.

1995 • 159 citations

Mapping of replication initiation sites in mammalian genomes by two-dimensional gel analysis: stabilization and enrichment of replication intermediates by isolation on the nuclear matrix.

1991 • 153 citations

Changes in gene position are accompanied by a change in time of replication

1984 • 147 citations

ORC- and Cdc6-dependent complexes at active and inactive chromosomal replication origins in Saccharomyces cerevisiae.

1996 • 141 citations

The mouse IgH 3′‐enhancer

1991 • 139 citations

An enhancer at the 3′ end of the mouse immunoglobulin heavy chain locus

1991 • 116 citations

Two-dimensional gel electrophoretic method for mapping DNA replicons.

1988 • 111 citations

Identification of 3α-hs4, a novel Ig heavy chain enhancer element regulated at multiple stages of B cell differentiation

1995 • 101 citations

Rate of replication of the murine immunoglobulin heavy-chain locus: evidence that the region is part of a single replicon.

1987 • 97 citations

The Immunoglobulin Heavy Chain Locus Contains Another B-Cell-Specific 3' Enhancer Close to the α Constant Region

1993 • 92 citations

Nucleotide sequence of the BALB/c mouse β-globin complex

1989 • 89 citations

Asynchronous DNA replication within the human beta-globin gene locus.

1988 • 87 citations

Constitutive binding of EBNA1 protein to the Epstein-Barr virus replication origin, oriP, with distortion of DNA structure during latent infection.

1993 • 84 citations

Immunoglobulin gene transcription ceases upon deletion of a distant enhancer.

1995 • 79 citations

Myeloma Mutant with a Novel 3′ Flanking Region: Loss of Normal Sequence and Insertion of Repetitive Elements Leads to Decreased Transcription but Normal Processing of the Alpha Heavy-Chain Gene Products

1986 • 66 citations

Immunoglobulin heavy chain enhancer is located near or in an initiation zone of chromosomal DNA replication.

1993 • 63 citations

Dyad symmetry within the mouse 3' IgH regulatory region includes two virtually identical enhancers (C alpha3'E and hs3).

1997 • 61 citations

Eukaryotic replicators and associated protein complexes

1995 • 46 citations

Purification of Circular DNA Using Benzoylated Naphthoylated DEAE-Cellulose

1985 • 21 citations

12 Temporal Order of DNA Replication

1996 • 19 citations