Homology-directed repair is a major double-strand break repair pathway in mammalian cells

Molecular Cloning. A Laboratory Manual

1983 • 27,328 citations

The double-strand-break repair model for recombination

1983 • 2,468 citations

A novel repeated element with Z-DNA-forming potential is widely found in evolutionarily diverse eukaryotic genomes.

1982 • 759 citations

Introduction of double-strand breaks into the genome of mouse cells by expression of a rare-cutting endonuclease.

1994 • 734 citations

Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells.

1994 • 550 citations

Induction of Homologous Recombination in Mammalian Chromosomes by Using the I-SceI System of Saccharomyces cerevisiae

1995 • 438 citations

Genetic manipulation of genomes with rare-cutting endonucleases

1996 • 385 citations

Evolution and distribution of (GT)n repetitive sequences in mammalian genomes

1991 • 379 citations

DNA double-strand break repair and V(D)J recombination: involvement of DNA-PK

1995 • 344 citations

Introduction of Double-Strand Breaks into the Genome of Mouse Cells by Expression of a Rare-Cutting Endonuclease

1994 • 321 citations

LOSS OF CONSTITUTIONAL HETEROZYGOSITY IN HUMAN CANCER

1991 • 318 citations

The sequence (dC-dA)n X (dG-dT)n forms left-handed Z-DNA in negatively supercoiled plasmids.

1983 • 314 citations

Gene Conversion Tracts from Double-Strand Break Repair in Mammalian Cells

1998 • 305 citations

Repair of Site-Specific Double-Strand Breaks in a Mammalian Chromosome by Homologous and Illegitimate Recombination

1997 • 270 citations

Homologous recombination and the roles of double-strand breaks

1995 • 234 citations

Double-strand breaks at the target locus stimulate gene targeting in embryonic stem cells

1995 • 219 citations

In vivo biochemistry: Physical monitoring of recombination induced by site‐specific endonucleases

1995 • 191 citations

Chromosomal double-strand break repair in Ku80-deficient cells.

1996 • 191 citations

Loss of heterozygosity induced by a chromosomal double-strand break

1997 • 183 citations

The Mismatch Repair System Reduces Meiotic Homeologous Recombination and Stimulates Recombination-Dependent Chromosome Loss

1996 • 178 citations

Chromosomal Double-Strand Breaks Induce Gene Conversion at High Frequency in Mammalian Cells

1997 • 173 citations

Homologous integration in mammalian cells without target gene selection.

1988 • 172 citations

ALL-1 tandem duplication in acute myeloid leukemia with a normal karyotype involves homologous recombination between Alu elements.

1994 • 167 citations

Intermolecular recombination between DNAs introduced into mouse L cells is mediated by a nonconservative pathway that leads to crossover products.

1990 • 120 citations

Illegitimate recombination induced by DNA double-strand breaks in a mammalian chromosome.

1994 • 117 citations

High frequency of homologous recombination in mammalian cells between endogenous and introduced SV40 genomes

1985 • 100 citations

Repair of a specific double-strand break generated within a mammalian chromosome by yeast endonuclease I-Scel

1994 • 99 citations

Meiotic Recombination in Yeast: Coronation of the Double-Strand-Break Repair Model

1996 • 93 citations

Illegitimate Recombination Induced by DNA Double-Strand Breaks in a Mammalian Chromosome

1994 • 49 citations

Intermolecular Recombination between DNAs Introduced into Mouse L Cells Is Mediated by a Nonconservative Pathway That Leads to Crossover Products

1990 • 21 citations