High frequency of homologous recombination in mammalian cells between endogenous and introduced SV40 genomes

A rapid alkaline extraction procedure for screening recombinant plasmid DNA

1979 • 15,511 citations

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

A new technique for the assay of infectivity of human adenovirus 5 DNA

1973 • 9,740 citations

[12] One-step gene disruption in yeast

1983 • 3,302 citations

SV40-transformed simian cells support the replication of early SV40 mutants

1981 • 2,564 citations

The double-strand-break repair model for recombination

1983 • 2,468 citations

Expression of a β-globin gene is enhanced by remote SV40 DNA sequences

1981 • 1,677 citations

Yeast transformation: a model system for the study of recombination.

1981 • 1,491 citations

A mechanism for gene conversion in fungi

1964 • 1,459 citations

A lymphocyte-specific cellular enhancer is located downstream of the joining region in immunoglobulin heavy chain genes

1983 • 1,449 citations

Biochemical transfer of single-copy eucaryotic genes using total cellular DNA as donor

1978 • 1,284 citations

A very strong enhancer is located upstream of an immediate early gene of human cytomegalovirus

1985 • 1,155 citations

A mechanism for gene conversion in fungi

2007 • 1,149 citations

A general model for genetic recombination.

1975 • 890 citations

High efficiency polyoma DNA transfection of chloroquine treated cells

1983 • 711 citations

Developmentally controlled and tissue-specific expression of unrearranged VH gene segments

1985 • 710 citations

A general method for site-directed mutagenesis in prokaryotes

1981 • 697 citations

Multiple specific contacts between a mammalian transcription factor and its cognate promoters

1984 • 565 citations

DNA Tumor Viruses

1982 • 550 citations

[14] Genetic applications of yeast transformation with linear and gapped plasmids

1983 • 503 citations

HOMOLOGOUS PAIRING AND STRAND EXCHANGE IN GENETIC RECOMBINATION

1982 • 443 citations

Yeast recombination: the association between double-strand gap repair and crossing-over.

1983 • 432 citations

Embryonic lethal mutation in mice induced by retrovirus insertion into the α1(I) collagen gene

1983 • 422 citations

Absence of nucleosomes in a fraction of SV40 chromatin between the origin of replication and the region coding for the late leader RNA

1980 • 372 citations

[13] Eviction and transplacement of mutant genes in yeast

1983 • 305 citations

Direct transfer of cloned genes from bacteria to mammalian cells.

1980 • 291 citations

A stretch of “late” SV40 viral DNA about 400 bp long which includes the origin of replication is specifically exposed in SV40 minichromosomes

1979 • 278 citations

A nucleosome-free region in SV40 minichromosomes

1980 • 254 citations

Polyoma virus DNA replication requires an enhancer

1984 • 253 citations

Homologous recombination between plasmids in mammalian cells can be enhanced by treatment of input DNA.

1984 • 251 citations

A foreign β-globin gene in transgenic mice: Integration at abnormal chromosomal positions and expression in inappropriate tissues

1983 • 245 citations

An SV40 “enhancer trap” incorporates exogenous enhancers or generates enhancers from its own sequences

1984 • 223 citations

Expression of early genes of origin-defective mutants of simian virus 40.

1980 • 205 citations

Replacement and amplification of bacterial genes with sequences altered in vitro.

1983 • 181 citations

Recombination in mouse L cells between DNA introduced into cells and homologous chromosomal sequences.

1985 • 165 citations

Prenatal lethalities in mice homozygous for human growth hormone gene sequences integrated in the germ line

1983 • 161 citations

High-Efficiency Ligation and Recombination of DNA Fragments by Vertebrate Cells

1983 • 148 citations

Deletion of an essential gene in Escherichia coli by site-specific recombination with linear DNA fragments

1984 • 148 citations

Recombination During Gene Transfer into Mouse Cells Can Restore the Function of Deleted Genes

1983 • 148 citations

Simian virus 40 enhancer increases number of RNA polymerase II molecules on linked DNA

1985 • 138 citations

Homologous recombination in mammalian cells mediates formation of a functional gene from two overlapping gene fragments.

1983 • 129 citations

Nonreciprocal exchanges of information between DNA duplexes coinjected into mammalian cell nuclei.

1985 • 120 citations

Homologous and nonhomologous recombination in monkey cells.

1983 • 114 citations

Homologous Recombination between Defective neo Genes in Mouse 3T6 Cells

1984 • 111 citations

Isolation and characterization of temperature-sensitive mutants of Simian Virus 40

1972 • 96 citations

A Mammalian Host-Vector System That Regulates Expression and Amplification of Transfected Genes by Temperature Induction

1985 • 95 citations

Genetic recombination : thinking about it in phage and fungi

1979 • 92 citations

Genetic Recombination: Thinking About It in Phage and Fungi

1980 • 87 citations

Simian virus 40 enhancer increases RNA polymerase density within the linked gene

1985 • 79 citations

Expression of complete transplantation antigens by mammalian cells transformed with truncated class I genes

1983 • 70 citations

Segments of simian virus 40 DNA spanning most of the leader sequence of the major late viral messenger RNA are dispensable.

1979 • 67 citations

Rapid assay for extrachromosomal homologous recombination in monkey cells.

1985 • 55 citations

Recombination between a defective retrovirus and homologous sequences in host DNA: reversion by patch repair

1985 • 53 citations

Recovery of myc-specific sequences by a partially transformation-defective mutant of avian myelocytomatosis virus, MC29, correlates with the restoration of transforming activity.

1982 • 39 citations

Low molecular weight RNAs with homologies to cellular DNA at sites of adenovirus DNA insertion in hamster or mouse cells.

1984 • 31 citations

Isolation of 16L virus: a rapidly transforming sarcoma virus from an avian leukosis virus-induced sarcoma.

1982 • 26 citations

Homologous recombination between a defective virus and a chromosomal sequence in mammalian cells.

1985 • 22 citations

Recombination Between Endogenous and Exogenous Simian Virus 40 Genes. II. Biochemical Evidence for Genetic Exchange

1977 • 22 citations

Recombination between endogenous and exogenous simian virus 40 genes III. Rescue of SV40 tsA and tsBC mutants by passage in permissive transformed monkey lines

1980 • 21 citations

Recovered src genes are polymorphic and contain host markers

1980 • 20 citations

Plasmids Containing Mouse rDNA Do Not Recombine with Cellular Ribosomal Genes when Introduced into Cultured Mouse Cells

1984 • 18 citations

Recombination Between Endogenous and Exogenous Simian Virus 40 Genes. I. Rescue of a Simian Virus 40 Temperature-Sensitive Mutant by Passage in Permissive Transformed Monkey Lines

1977 • 16 citations

Linear simian virus 40 DNA fragments exhibit a propensity for rolling-circle replication.

1985 • 9 citations

Plasmids containing mouse rDNA do not recombine with cellular ribosomal genes when introduced into cultured mouse cells.

1984 • 9 citations