Neurochemical abnormalities in Alzheimer’s disease and Parkinson’s disease — a comparative review

Mitochondrial Complex I Deficiency in Parkinson's Disease

1990 • 2,147 citations

Verteilung Von Noradrenalin Und Dopamin (3-Hydroxytyramin) Im Gehirn Des Menschen Und Ihr Verhalten Bei Erkrankungen Des Extrapyramidalen Systems

1960 • 1,863 citations

Basal Lipid Peroxidation in Substantia Nigra Is Increased in Parkinson's Disease

1989 • 1,369 citations

Transition Metals, Ferritin, Glutathione, and Ascorbic Acid in Parkinsonian Brains

1989 • 1,367 citations

Parkinson's disease: A disorder due to nigral glutathione deficiency?

1982 • 746 citations

Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain

1988 • 738 citations

Anatomic and Disease Specificity of NADH CoQ₁ Reductase (Complex I) Deficiency in Parkinson's Disease

1990 • 676 citations

THE CHOLINERGIC HYPOTHESIS—TEN YEARS ON

1986 • 563 citations

A Selective Increase in Particulate Superoxide Dismutase Activity in Parkinsonian Substantia Nigra

1989 • 445 citations

Idiopathic Parkinson's disease, progressive supranuclear palsy and glutathione metabolism in the substantia nigra of patients

1986 • 364 citations

Decreased pyruvate dehydrogenase complex activity in Huntington and Alzheimer brain

1983 • 355 citations

The effect of age on the activity and molecular properties of human brain monoamine oxidase

1980 • 342 citations

Alterations in L-Glutamate Binding in Alzheimer's and Huntington's Diseases

1985 • 334 citations

Glutathione peroxidase activity in Parkinson's disease brain

1985 • 301 citations

Dementia of the Alzheimer's Type: Changes in Hippocampal L‐[³H]Glutamate Binding

1987 • 281 citations

Enzyme Activities in Relation to pH and Lactate in Postmortem Brain in Alzheimer‐Type and Other Dementias

1990 • 252 citations

Oxygen toxicity protecting enzymes in Parkinson's disease

1988 • 239 citations

Coenzyme a-acetylating enzymes in Alzheimer's disease: Possible cholinergic ‘compartment’ of pyruvate dehydrogenase

1980 • 232 citations

Density and distribution of NMDA receptors in the human hippocampus in Alzheimer's disease

1986 • 215 citations

Neurochemical activities in human temporal lobe related to aging and Alzheimer-type changes

1981 • 211 citations

Evidence of Glutamatergic Denervation and Possible Abnormal Metabolism in Alzheimer's Disease

1988 • 200 citations

Alzheimer's disease: Changes in hippocampal N-methyl-d-aspartate, quisqualate, neurotensin, adenosine, benzodiazepine, serotonin and opioid receptors—an autoradiographic study

1990 • 195 citations

An immunochemical study of the pyruvate dehydrogenase deficit in Alzheimer's disease brain

1985 • 164 citations

Region-specific loss of glutamate innervation in Alzheimer's disease

1987 • 147 citations

A post-mortem study of noradrenergic, serotonergic and GABAergic neurons in Alzheimer's disease

1988 • 146 citations

Topographical distribution of neurochemical changes in Alzheimer's disease

1988 • 137 citations

A postmortem study of amino acid neurotransmitters in Alzheimer's disease

1986 • 134 citations

Regional Metal Concentrations in Parkinson's Disease, Other Chronic Neurological Diseases, and Control Brains

1989 • 131 citations

Postmortem changes in mitochondrial respiratory enzymes in brain and a preliminary observation in Parkinson's disease

1990 • 127 citations

Amino acids, glutathione, and glutathione transferase activity in the brains of patients with Alzheimer's disease

1987 • 119 citations

Excitatory amino acid-releasing and cholinergic neurones in Alzheimer's disease

1986 • 118 citations

Reduced Glycine Stimulation of [³H]MK‐801 Binding in Alzheimer's Disease

1989 • 117 citations

The selectivity of the reduction of serotonin S2 receptors in Alzheimer-type dementia

1986 • 114 citations

Superoxide dismutase isoenzymes in normal brains and in brains from patients with dementia of Alzheimer type

1985 • 110 citations

Regional distribution of amino acid transmitters in postmortem brains of presenile and senile dementia of Alzheimer type

1986 • 107 citations

Regional distribution of pre- and postsynaptic glutamatergic function in Alzheimer's disease

1988 • 85 citations

Regional changes in [3H]d-aspartate and [3H]TCP binding sites in Alzheimer's disease brains

1988 • 76 citations

Hippocampal Free Amino Acids in Alzheimer's Disease

1980 • 74 citations

Brain gamma-aminobutyrate aminotransferase (GABA-T) and monoamine oxidase (MAO) in patients with Alzheimer's disease

1992 • 65 citations

A preliminary study of free amino acids in the postmorten temporal cortex from Alzheimer-type dementia patients

1984 • 63 citations

Loss of glycine-dependent radioligand binding to the receptor complex in patients with Alzheimer's disease

1989 • 63 citations

Biochemical fundamentals of Parkinson's disease.

1988 • 58 citations

Neurotransmitter dysfunction and atrophy of the caudate nucleus in Alzheimer's disease.

1984 • 55 citations

Sodium dependent d-[3H]aspartate binding in cerebral cortex in patients with Alzheimer's and Parkinson's diseases

1987 • 46 citations

[3H]MK-801 binding in Alzheimer's disease

1988 • 44 citations

Striatal GABAergic Neuronal Activity Is Not Reduced in Parkinson's Disease

1983 • 42 citations

Characterisation, Density, and Distribution of Kainate Receptors in Normal and Alzheimer's Diseased Human Brain

1989 • 37 citations

Dementia, parkinsonism, and motor neuron disease: Neurochemical and neuropathological correlates

1988 • 36 citations

Glutamate deficits in Alzheimer's disease

1987 • 34 citations

Senile Dementia and Alzheimer's disease: Lack of changes of the cortical content of Quinolinic Acid

1986 • 30 citations

Glycine Receptors in the Human Substantia Nigra as Defined by [³H]Strychnine Binding

1982 • 29 citations

Sodium-dependent glutamate binding in senile dementia

1987 • 18 citations

Brain quinolinic acid in Alzheimer's dementia

1989 • 16 citations

γ-GLUTAMYLTRANSFERASE

1987 • 15 citations

A correlative study on hippocampal cation shifts and amino acids and clinico-pathological data in Alzheimer's disease

1987 • 15 citations

[3H]Kainic acid binding and choline acetyltransferase activity in alzheimer's dementia

1984 • 13 citations

Neurotransmitter and Metabolic Dysfunction in Alzheimer�s Dementia: Relationship to Histopathological Features

2015 • 11 citations

Region-specific defects in glutamate and γ-aminobutyric acid innervation in Alzheimer's disease

1987 • 5 citations

Brain enzymes in agonal state and dementia

1989 • 4 citations

HIPPOCAMPAL CATION SHIFTS AND AMINO-ACIDS AND CLINICOPATHOLOGICAL DATA IN ALZHEIMERS-DISEASE

1987 • 3 citations

Deleted Work

1955 • 0 citations