The transcriptional regulatory code of eukaryotic cells – insights from genome-wide analysis of chromatin organization and transcription factor binding

Finishing the euchromatic sequence of the human genome

2004 • 4,741 citations

Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells

2005 • 4,388 citations

Capturing Chromosome Conformation

2002 • 3,550 citations

The Transcriptional Landscape of the Mammalian Genome

2005 • 3,444 citations

A gene atlas of the mouse and human protein-encoding transcriptomes

2004 • 3,443 citations

Transcriptional Regulatory Networks in Saccharomyces cerevisiae

2002 • 2,967 citations

The ENCODE (ENCyclopedia Of DNA Elements) Project

2004 • 2,327 citations

Transcriptional regulatory code of a eukaryotic genome

2004 • 2,174 citations

Genomic Maps and Comparative Analysis of Histone Modifications in Human and Mouse

2005 • 1,497 citations

Genome-wide Map of Nucleosome Acetylation and Methylation in Yeast

2005 • 1,418 citations

Chromosome-Wide Mapping of Estrogen Receptor Binding Reveals Long-Range Regulation Requiring the Forkhead Protein FoxA1

2005 • 1,328 citations

Control of Pancreas and Liver Gene Expression by HNF Transcription Factors

2004 • 1,293 citations

Transcriptional Maps of 10 Human Chromosomes at 5-Nucleotide Resolution

2005 • 1,152 citations

A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome

2006 • 1,137 citations

Genome-Scale Identification of Nucleosome Positions in S. cerevisiae

2005 • 1,113 citations

Targeted Recruitment of Set1 Histone Methylase by Elongating Pol II Provides a Localized Mark and Memory of Recent Transcriptional Activity

2003 • 1,096 citations

Unbiased Mapping of Transcription Factor Binding Sites along Human Chromosomes 21 and 22 Points to Widespread Regulation of Noncoding RNAs

2004 • 1,079 citations

Global Identification of Human Transcribed Sequences with Genome Tiling Arrays

2004 • 1,020 citations

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

2005 • 977 citations

A high-resolution map of active promoters in the human genome

2005 • 922 citations

The histone modification pattern of active genes revealed through genome-wide chromatin analysis of a higher eukaryote

2004 • 788 citations

Molecular biology of the cell

2020 • 779 citations

Evidence for nucleosome depletion at active regulatory regions genome-wide

2004 • 745 citations

Defining the CREB Regulon

2004 • 708 citations

Histone Variant H2A.Z Marks the 5′ Ends of Both Active and Inactive Genes in Euchromatin

2005 • 669 citations

Serial Regulation of Transcriptional Regulators in the Yeast Cell Cycle

2001 • 664 citations

Mapping Global Histone Acetylation Patterns to Gene Expression

2004 • 620 citations

Genome-Wide Dynamics of Htz1, a Histone H2A Variant that Poises Repressed/Basal Promoters for Activation through Histone Loss

2005 • 530 citations

A global transcriptional regulatory role for c-Myc in Burkitt's lymphoma cells

2003 • 524 citations

Single-Nucleosome Mapping of Histone Modifications in S. cerevisiae

2005 • 497 citations

Genome-scale profiling of histone H3.3 replacement patterns

2005 • 493 citations

Silencing of human polycomb target genes is associated with methylation of histone H3 Lys 27

2004 • 485 citations

Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes

2005 • 484 citations

Distinct localization of histone H3 acetylation and H3-K4 methylation to the transcription start sites in the human genome

2004 • 475 citations

Active chromatin domains are defined by acetylation islands revealed by genome-wide mapping

2005 • 445 citations

An initial blueprint for myogenic differentiation

2005 • 436 citations

Variant Histone H2A.Z Is Globally Localized to the Promoters of Inactive Yeast Genes and Regulates Nucleosome Positioning

2005 • 427 citations

Global nucleosome occupancy in yeast.

2004 • 361 citations

Global and Hox-specific roles for the MLL1 methyltransferase

2005 • 357 citations

Histone variants: deviants?

2005 • 356 citations

Identification of unknown target genes of human transcription factors using chromatin immunoprecipitation

2002 • 352 citations

Chromatin profiling using targeted DNA adenine methyltransferase

2001 • 317 citations

Distribution of NF-κB-binding sites across human chromosome 22

2003 • 302 citations

ASSEMBLY OF VARIANT HISTONES INTO CHROMATIN

2005 • 278 citations

High-resolution genome-wide mapping of histone modifications

2004 • 208 citations

Genome-Wide Analysis of Protein-DNA Interactions

2006 • 174 citations

CREB Binds to Multiple Loci on Human Chromosome 22

2004 • 172 citations

Distinct HP1 and Su(var)3-9 complexes bind to sets of developmentally coexpressed genes depending on chromosomal location

2003 • 167 citations

ChIPOTle: a user-friendly tool for the analysis of ChIP-chip data.

2005 • 152 citations

A hidden Markov model for analyzing ChIP-chip experiments on genome tiling arrays and its application to p53 binding sequences

2005 • 117 citations

Mapping DNA-protein interactions in large genomes by sequence tag analysis of genomic enrichment

2004 • 104 citations

Use of Chromatin Immunoprecipitation Assays in Genome-Wide Location Analysis of Mammalian Transcription Factors

2003 • 93 citations

Genomic mapping of RNA polymerase II reveals sites of co-transcriptional regulation in human cells.

2005 • 90 citations

Direct isolation and identification of promoters in the human genome

2005 • 86 citations

ChIP‐chip: Data, Model, and Analysis

2007 • 79 citations

Control of Transcription through Intragenic Patterns of Nucleosome Composition

2005 • 70 citations

Chipper: discovering transcription-factor targets from chromatin immunoprecipitation microarrays using variance stabilization.

2005 • 39 citations

[Genome network project: a national project in post-sequence era].

2004 • 1 citations