Adenoviral Bak overexpression mediates caspase-dependent tumor killing.

Bcl-2 and the regulation of programmed cell death

1994 • 2,346 citations

BAX-induced cell death may not require interleukin 1β-converting enzyme-like proteases

1996 • 911 citations

Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death.

1993 • 855 citations

Modulation of apoptosis by the widely distributed Bcl-2 homologue Bak

1995 • 514 citations

Adenovirus-Mediated p53 Gene Transfer in Advanced Non-Small-Cell Lung Cancer

1999 • 492 citations

Adenovirus-mediated p53 gene transfer in patients with advanced recurrent head and neck squamous cell carcinoma.

1998 • 379 citations

Bak BH3 Peptides Antagonize Bcl-xL Function and Induce Apoptosis through Cytochrome c-independent Activation of Caspases

1999 • 255 citations

Alteration of caspase-3 (CPP32/Yama/apopain) in wild-type MCF-7, breast cancer cells.

1999 • 138 citations

Bik and Bak Induce Apoptosis Downstream of CrmA but Upstream of Inhibitor of Apoptosis

1997 • 72 citations

Up-regulation of the proapoptotic mediators Bax and Bak after adenovirus-mediated p53 gene transfer in lung cancer cells.

2000 • 70 citations

Antitumor Activity of bax and p53 Naked Gene Transfer in Lung Cancer: In Vitro and In Vivo Analysis

1998 • 52 citations

Bak can accelerate chemotherapy-induced cell death independently of its heterodimerization with Bcl-XL and Bcl-2

1997 • 50 citations

Evaluation of GAL4/TATA in Vivo

1998 • 48 citations