Prevention of radiocontrast nephropathy with N-acetylcysteine in patients with chronic kidney disease: a meta-analysis of randomized, controlled trials

Quantitative Synthesis in Systematic Reviews

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Hospital-acquired renal insufficiency

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1988 • 1,650 citations

Incidence and Prognostic Importance of Acute Renal Failure After Percutaneous Coronary Intervention

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Prevention of Radiographic-Contrast-Agent–Induced Reductions in Renal Function by Acetylcysteine

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The Effect of Acute Renal Failure on Mortality

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Acute Renal Failure

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Hypoxia of the Renal Medulla — Its Implications for Disease

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Cumulative Meta-Analysis of Therapeutic Trials for Myocardial Infarction

1992 • 1,132 citations

Nephrotoxic Effects in High-Risk Patients Undergoing Angiography

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Contrast Material-Induced Renal Failure in Patients with Diabetes Mellitus, Renal Insufficiency, or Both

1989 • 1,006 citations

Nephrotoxicity of ionic and nonionic contrast media in 1196 patients: A randomized trial

1995 • 914 citations

Metaanalysis of the relative nephrotoxicity of high- and low-osmolality iodinated contrast media.

1993 • 733 citations

Acetylcysteine for Prevention of Acute Deterioration of Renal Function Following Elective Coronary Angiography and Intervention

2003 • 448 citations

Acetylcysteine and contrast agent-associated nephrotoxicity

2002 • 383 citations

Acetylcysteine to prevent angiography-related renal tissue injury (the APART trial)

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A rapid protocol for the prevention of contrast-induced renal dysfunction: the RAPPID study

2003 • 356 citations

Clinical Pharmacokinetics of N-Acetylcysteine

1991 • 338 citations

Radiocontrast medium-induced declines in renal function: a role for oxygen free radicals

1990 • 322 citations

Incidence, risk factors, and clinical course of acute renal insufficiency after cardiac catheterization in patients 70 years of age or older. A prospective study

1990 • 318 citations

A randomized controlled trial of N-acetylcysteine to prevent contrast nephropathy in cardiac angiography

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Factors Associated With Failure to Publish Large Randomized Trials Presented at an Oncology Meeting

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Acetylcysteine protects against acute renal damage in patients with abnormal renal function undergoing a coronary procedure

2002 • 300 citations

Prospective randomized study of N‐acetylcysteine, fenoldopam, and saline for prevention of radiocontrast‐induced nephropathy

2002 • 274 citations

Cardiovascular and Renal Toxicity of a Nonionic Radiographic Contrast Agent after Cardiac Catheterization

1989 • 255 citations

Risks associated with renal dysfunction in patients in the coronary care unit

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Incidence, Risk Factors, and Clinical Course of Acute Renal Insufficiency After Cardiac Catheterization in Patients 70 Years of Age or Older

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Effects of dopamine and aminophylline on contrast-induced acute renal failure after coronary angioplasty in patients with preexisting renal insufficiency

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PREPARED: PREParation for Angiography in REnal Dysfunction

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N-acetyl cysteine ameliorates ischemic renal failure

1997 • 219 citations

N-acetyl-<scp>l</scp>-cysteine improves renal medullary hypoperfusion in acute renal failure

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N-acetylcysteine improves coronary and peripheral vascular function

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N-acetylcysteine ameliorates renal microcirculation: Studies in rats

2003 • 91 citations

Radiocontrast nephropathy: identifying the high-risk patient and the implications of exacerbating renal function.

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The introduction of low-osmolar contrast agents in radiology. Medical, economic, legal, and public policy issues.

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PROTECTIVE EFFECT OF N-ACETYL-L-CYSTEINE ON THE RENAL FAILURE INDUCED BY INFERIOR VENA CAVA OCCLUSION

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The Introduction of Low-Osmolar Contrast Agents in Radiology

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Contrast medium-induced adverse reactions: economic outcome.

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Prevention of radiocontrast-induced nephropathy with N-acetylcysteine in patients undergoing coronary angiography.

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The role of mucomyst administration prior to percutaneous interventions on renal function in patients with chronic renal failure

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Randomized comparison of fenoldopam and N-acetylcysteine to saline in the prevention of radio-contrast induced nephropathy

2003 • 22 citations

Alterations of glomerular and extracellular glutathione peroxidase levels in patients and rats with focal segmental glomerulosclerosis

2001 • 17 citations

Acetylcysteine for radiocontrast nephropathy

2001 • 10 citations

Oral N-acetylcysteine administered immediately prior to routine percutaneous coronary procedures ameliorates contrast-induced nephrotoxicity

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Prophylactic acetylcysteine is not effective in preventing contrast-induced nephropathy following coronary angiography

2003 • 3 citations

Radiocontrast nephropathy

2002 • 3 citations

Will this magic bullet fly true?

2001 • 3 citations

Hydration versus N-acetylcysteine for protection of renal function in patients with renal insufficiency undergoing percutaneous coronary intervention

2003 • 3 citations

The effect of acetylcysteine on renal function in elderly high-risk patients exposed to arteriographic contrast dye

2003 • 2 citations