Clinical Pharmacokinetics of N-Acetylcysteine

Pharmacokinetics of N-acetylcysteine in man

1986 • 333 citations

Pharmacokinetics and bioavailability of reduced and oxidized N-acetylcysteine

1988 • 329 citations

Lung Protection by a Thiol-Containing Antioxidant: N-Acetylcysteine

1986 • 266 citations

Oral acetylcysteine reduces exacerbation rate in chronic bronchitis: report of a trial organized by the Swedish Society for Pulmonary Diseases.

1983 • 217 citations

High-performance liquid chromatography and fluorometric detection of biologically important thiols, derivatized with ammonium 7-fluorobenzo-2-oxa-1,3-diazole-4-sulphonate (SBD-F)

1983 • 156 citations

The Treatment of Acetaminophen Poisoning

1983 • 153 citations

Toxicological, pharmacokinetic and metabolic studies on acetylcysteine.

1980 • 117 citations

Clinical safety of high oral doses of acetylcysteine.

1983 • 91 citations

No penetration of orally administered N-acetylcysteine into bronchoalveolar lavage fluid.

1987 • 88 citations

Metabolic studies with acetylcysteine

1966 • 87 citations

Acetylcysteine: A Drug with an Interesting Past and a Fascinating Future

1986 • 86 citations

Pharmacokinetics and bioavailability of oral acetylcysteine in healthy volunteers.

1989 • 75 citations

The staging of lung cancer.

1983 • 53 citations

Determination of 3-mercaptolactate, mercaptoacetate and N-acetylcysteine in urine by gas chromatography

1979 • 52 citations

Studies on the metabolism of isopnosphamide (NSC-109724) in man.

1976 • 50 citations

Pharmacokinetics of Oral Acetylcysteine

1978 • 50 citations

Colorimetric Determination of Acetylcysteine, Penicillamine, and Mercaptopropionylglycine in Pharmaceutical Dosage Forms

1982 • 47 citations

Long-term oral acetylcysteine in chronic bronchitis. a double-blind controlled study.

1980 • 44 citations

Effect of activated charcoal administration on acetylcysteine serum levels in humans

1981 • 43 citations

Determination of N-acetylcysteine, intact and oxidized, in plasma by column liquid chromatography and post-column derivatization

1987 • 36 citations

Methodologies for the analysis of reduced and oxidized N‐acetylcysteine in biological systems

1987 • 35 citations

Adsorption of Oral Antidotes for Acetaminophen Poisoning (Methionine and N-Acetylcysteine) by Activated Charcoal

1981 • 31 citations

Studies in the sulphur metabolism of the dog

1933 • 27 citations

Improved method for the determination of N-acetylcysteine in human plasma by high-performance liquid chromatography

1985 • 26 citations

Determination of non-protein-bound N-acetylcysteine in plasma by high-performance liquid chromatography

1984 • 25 citations

Studies in the Sulphur Metabolism of the Dog

1926 • 25 citations

Determination of n-acetyl-L-cysteine in biological fluids

1984 • 24 citations

Measurement of penicillamine and N-acetylcysteine in human blood by high-performance liquid chromatography and electrochemical detection

1986 • 24 citations

The efficacy of N-acetylcysteine in preventing doxorubicin-induced cardiomyopathy in dogs.

1983 • 21 citations

Comparison of electroclhemical detection methods in liquid chromatography for the determination of N-acetylcysteine in plasma

1986 • 20 citations

High-Performance Liquid Chromatographic Assay for N-Acetylcysteine in Plasma and Urine

1984 • 19 citations

Biological properties of acetylcysteine: assay development and pharmacokinetic studies.

1980 • 15 citations

High-performance liquid chromatographic determination of N-acetylcysteine in human serum following acetaminophen overdosage

1986 • 13 citations

A Sensitive Fluorometric Determination of N-Acetyl-L-cysteine in Biological Fluids by High Performance Liquid Chromatography

1981 • 13 citations

N-acetylcysteine prevents the doxorubicin-induced decrease of cyclic GMP.

1983 • 12 citations

Pharmacokinetics of oral acetylcysteine: Absorption, binding and metabolism in patients with respiratory disorders

1980 • 8 citations