Cytokine mRNA gene expression in active and nonactive pulmonary sarcoidosis

Pulmonary sarcoidosis

2018 • 894 citations

Gamma interferon is spontaneously released by alveolar macrophages and lung T lymphocytes in patients with pulmonary sarcoidosis.

1985 • 462 citations

Pulmonary Sarcoidosis: A Disease Characterized and Perpetuated by Activated Lung T-Lymphocytes

1981 • 426 citations

Activation of human macrophages. Comparison of other cytokines with interferon-gamma.

1984 • 362 citations

Spontaneous Release of Interleukin-2 by Lung T Lymphocytes in Active Pulmonary Sarcoidosis

1983 • 358 citations

Enhanced expression of IL-12 associated with Th1 cytokine profiles in active pulmonary sarcoidosis.

1996 • 331 citations

Maintenance of Granuloma Formation in Pulmonary Sarcoidosis by T Lymphocytes within the Lung

1980 • 250 citations

Current Concepts of the Pathogenesis of Sarcoidosis1,2

2015 • 239 citations

Characterization of the inflammatory and immune effector cells in the lung parenchyma of patients with interstitial lung disease.

1981 • 233 citations

Release of interleukin-1 by alveolar macrophages of patients with active pulmonary sarcoidosis.

1984 • 210 citations

Release of tumor necrosis factor by alveolar macrophages of patients with sarcoidosis.

1990 • 163 citations

Localization of atrial natriuretic peptide mRNA and immunoreactivity in the rat heart and human atrial appendage.

1987 • 144 citations

Evidence for a Th1-like bronchoalveolar T-cell subset and predominance of interferon-gamma gene activation in pulmonary tuberculosis.

1994 • 106 citations

Alveolar macrophages from patients with beryllium disease and sarcoidosis express increased levels of mRNA for tumor necrosis factor-alpha and interleukin-6 but not interleukin-1 beta.

1994 • 103 citations

Anti-inflammatory cytokine release by alveolar macrophages in pulmonary sarcoidosis.

1996 • 96 citations

Alveolar T-cell subsets in pulmonary sarcoidosis. Correlation with disease activity and effect of steroid treatment.

1984 • 90 citations

Pulmonary sarcoidosis: patterns of cytokine release in vitro

1996 • 77 citations

Alveolar macrophage TNF-alpha release and BAL cell phenotypes in sarcoidosis.

1995 • 70 citations

Evidence of cells bearing interleukin-2 receptor at sites of disease activity in sarcoid patients.

1984 • 67 citations

Sarcoidosis and Other Granulomatous Diseases

1981 • 50 citations

Lack of immune deficiency in sarcoidosis: compartmentalisation of the immune response.

1987 • 43 citations

Significance of Interleukin 6 in Patients With Sarcoidosis

1994 • 40 citations

Fusion and Activation of Human Alveolar Macrophages Induced by Recombinant Interferon-γ and Their Suppression by Dexamethasone

1987 • 39 citations

Correlation of GM-CSF mRNA in bronchoalveolar fluid with indices of clinical activity in sarcoidosis.

1993 • 17 citations

Presence of mRNA for interferon-gamma (IFN-γ) in blood mononuclear cells is associated with an active stage I sarcoidosis

1995 • 11 citations

TNF alpha mRNA, but not IL-1 beta, is differentially expressed in lung macrophages of patients with active pulmonary sarcoidosis.

1994 • 9 citations