Conservation of glp-1 Regulation and Function in Nematodes

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

Molecular cloning: A laboratory manual

1990 • 85,659 citations

Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans

1998 • 14,674 citations

THE GENETICS OF CAENORHABDITIS ELEGANS

1974 • 14,589 citations

Notch Signaling: Cell Fate Control and Signal Integration in Development

1999 • 5,826 citations

Genome sequence of the nematode C-elegans: A platform for investigating biology

1998 • 3,265 citations

Notch-1 signalling requires ligand-induced proteolytic release of intracellular domain

1998 • 1,600 citations

Notch Signaling

1995 • 1,282 citations

The Shape of Life

1996 • 1,211 citations

The shape of life: genes, development, and the evolution of animal form

1996 • 1,017 citations

The ankyrin repeat: a diversity of interactions on a common structural framework

1999 • 806 citations

Structure of an IκBα/NF-κB Complex

1998 • 792 citations

Specific EGF repeats of Notch mediate interactions with Delta and serrate: Implications for notch as a multifunctional receptor

1991 • 770 citations

The Notch1 receptor is cleaved constitutively by a furin-like convertase

1998 • 720 citations

glp-1 Is required in the germ line for regulation of the decision between mitosis and meiosis in C. elegans

1987 • 684 citations

Intracellular Cleavage of Notch Leads to a Heterodimeric Receptor on the Plasma Membrane

1997 • 615 citations

The lin-12 locus specifies cell fates in caenorhabditis elegans

1983 • 598 citations

On the control of germ cell development in Caenorhabditis elegans

1981 • 593 citations

Structure of the p53 Tumor Suppressor Bound to the Ankyrin and SH3 Domains of 53BP2

1996 • 569 citations

Hundreds of ankyrin‐like repeats in functionally diverse proteins: Mobile modules that cross phyla horizontally?

1993 • 504 citations

Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene

1996 • 497 citations

Physical interaction between a novel domain of the receptor Notch and the transcription factor RBP-Jκ/Su(H)

1995 • 476 citations

Calcium Depletion Dissociates and Activates Heterodimeric Notch Receptors

2000 • 411 citations

lag-2 may encode a signaling ligand for the GLP-1 and LIN-12 receptors of C. elegans

1994 • 385 citations

PGL-1, a Predicted RNA-Binding Component of Germ Granules, Is Essential for Fertility in C. elegans

1998 • 355 citations

glp-1 and lin-12, genes implicated in distinct cell-cell interactions in C. elegans, encode similar transmembrane proteins

1989 • 345 citations

Soma-germline asymmetry in the distributions of embryonic RNAs in Caenorhabditis elegans

1994 • 340 citations

The glp-1 locus and cellular interactions in early C. elegans embryos

1987 • 335 citations

The novel Notch homologue mouse Notch 3 lacks specific epidermal growth factor-repeats and is expressed in proliferating neuroepithelium

1994 • 318 citations

Cellular interactions in early C. elegans embryos

1987 • 305 citations

THE LIN-12/Notch SIGNALING PATHWAY AND ITS REGULATION

1997 • 292 citations

The Structure of GABPα/β: An ETS Domain- Ankyrin Repeat Heterodimer Bound to DNA

1998 • 287 citations

Caenorhabditis elegans Is a Nematode

1998 • 281 citations

Germ-line tumor formation caused by activation of glp-1, a Caenorhabditis elegans member of the Notch family of receptors

1997 • 266 citations

Sequence of C. elegans lag-2 reveals a cell-signalling domain shared with Delta and Serrate of Drosophila

1994 • 260 citations

Reciprocal changes in expression of the receptor lin-12 and its ligand lag-2 prior to commitment in a C. elegans cell fate decision

1994 • 254 citations

Two homologous regulatory genes, lin-12 and glp-1, have overlapping functions

1991 • 252 citations

The Genomic Record of Humankind's Evolutionary Roots

1999 • 248 citations

GLP-1 is localized to the mitotic region of the C. elegans germ line

1994 • 247 citations

Genetic regulation of entry into meiosis in Caenorhabditis elegans

1998 • 236 citations

lag-1, a gene required for lin-12 and glp-1 signaling in Caenorhabditis elegans, is homologous to human CBF1 and Drosophila Su(H)

1996 • 232 citations

Translational control of maternal glp-1 mRNA establishes an asymmetry in the C. elegans embryo

1994 • 231 citations

The maternal genes apx-1 and glp-1 and establishment of dorsal-ventral polarity in the early C. elegans embryo

1994 • 227 citations

Mutations altering the structure of epidermal growth factor-like coding sequences at the Drosophila Notch locus

1987 • 217 citations

Structure and distribution of the Notch protein in developing Drosophila.

1989 • 208 citations

LAG-3 is a putative transcriptional activator in the C. elegans Notch pathway

2000 • 190 citations

Analysis of gain-of-function mutations of the lin-12 gene of Caenorhabditis elegans

1990 • 157 citations

Molecular basis of loss-of-function mutations in the glp-1 gene of Caenorhabditis elegans.

1992 • 151 citations

Altered Epidermal Growth Factor-like sequences provide evidence for a role of Notch as a receptor in cell fate decisions

1993 • 147 citations

Morphogenesis of the C. elegans hermaphrodite uterus

1996 • 146 citations

Motch A and Motch B—Two Mouse Notch Homologues Coexpressed in a Wide Variety of Tissues

1993 • 136 citations

The Gut Esterase Gene (ges-1) From the Nematodes Caenmorhabditis elegans and Caenorhabditis briggsae

1993 • 119 citations

18S ribosomal RNA gene phylogeny for some Rhabditidae related to Caenorhabditis.

1995 • 117 citations

Control of cell fate in C. elegans by a GLP-1 peptide consisting primarily of ankyrin repeats

1993 • 107 citations

Cloning, Analysis, and Chromosomal Localization of Notch-1, a Mouse Homolog of Drosophila Notch

1993 • 107 citations

Monoclonal antibodies which distinguish certain classes of neuronal and supporting cells in the nervous tissue of the nematode Caenorhabditis elegans

1985 • 99 citations

Structure of the cyclin-dependent kinase inhibitor p19Ink4d

1997 • 96 citations

The Caenorhabditis elegans lin-12 gene mediates induction of ventral uterine specialization by the anchor cell

1995 • 96 citations

Roles of the RAM and ANK domains in signaling by the C. elegans GLP-1 receptor.

1996 • 91 citations

Cell-cell interactions prevent a potential inductive interaction between soma and germline in C. elegans

1990 • 81 citations

glp-1 can substitute for lin-12 in specifying cell fate decisions in Caenorhabditis elegans

1993 • 80 citations

The Caenorhabditis elegans Sex Determination Gene mog-1 Encodes a Member of the DEAH-Box Protein Family

1999 • 76 citations

lin-12 and glp-1 are required zygotically for early embryonic cellular interactions and are regulated by maternal GLP-1 signaling in Caenorhabditis elegans

1996 • 66 citations

Carboxy-terminal truncation activates glp-1 protein to specify vulval fates in Caenorhabditis elegans

1991 • 66 citations

Regulatory Elements Required for Development of Caenorhabditis elegans Hermaphrodites Are Conserved in the tra-2 Homologue of C. remanei, a Male/Female Sister Species

2000 • 65 citations

Further evidence for function of the Drosophila Notch protein as a transmembrane receptor.

1993 • 57 citations

The buccal capsule of Aduncospiculum halicti (Nemata: Diplogasterina): an ultrastructural and molecular phylogenetic study

1997 • 51 citations

A Phylogenetic Analysis of Vertebrate and Invertebrate Notch-Related Genes

1995 • 36 citations

Genes Required for GLP-1 Asymmetry in the EarlyCaenorhabditis elegansEmbryo

1997 • 31 citations

Intragenic dominant suppressors of glp-1, a gene essential for cell-signaling in Caenorhabditis elegans, support a role for cdc10/SWI6/ankyrin motifs in GLP-1 function.

1993 • 15 citations

The Yin and Yang of Evo/Devo

1998 • 14 citations

Deleted Work

1955 • 0 citations