Assessing Lead Time of Selected Ovarian Cancer Biomarkers: A Nested Case–Control Study

Robust Locally Weighted Regression and Smoothing Scatterplots

1979 • 10,049 citations

Projecting Individualized Probabilities of Developing Breast Cancer for White Females Who Are Being Examined Annually

1989 • 3,239 citations

The Statistical Evaluation of Medical Tests for Classification and Prediction

2003 • 1,999 citations

Phases of Biomarker Development for Early Detection of Cancer

2001 • 1,572 citations

The case for early detection

2003 • 1,099 citations

Multi-site assessment of the precision and reproducibility of multiple reaction monitoring–based measurements of proteins in plasma

2009 • 1,001 citations

Three Biomarkers Identified from Serum Proteomic Analysis for the Detection of Early Stage Ovarian Cancer

2004 • 941 citations

Sensitivity and specificity of multimodal and ultrasound screening for ovarian cancer, and stage distribution of detected cancers: results of the prevalence screen of the UK Collaborative Trial of Ovarian Cancer Screening (UKCTOCS)

2009 • 794 citations

Genomic amplification of a decoy receptor for Fas ligand in lung and colon cancer

1998 • 781 citations

B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma

2006 • 705 citations

Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers.

1996 • 692 citations

The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma.

2003 • 690 citations

The Glycosylphosphatidylinositol Anchor: A Complex Membrane-Anchoring Structure for Proteins

2008 • 567 citations

Human Epididymis Protein 4 (HE4) Is a Secreted Glycoprotein that Is Overexpressed by Serous and Endometrioid Ovarian Carcinomas

2005 • 557 citations

Binding of Ovarian Cancer Antigen CA125/MUC16 to Mesothelin Mediates Cell Adhesion

2004 • 529 citations

Progress and Challenges in Screening for Early Detection of Ovarian Cancer

2004 • 446 citations

Comprehensive analysis of HE4 expression in normal and malignant human tissues

2006 • 408 citations

Mesothelin-MUC16 binding is a high affinity, N-glycan dependent interaction that facilitates peritoneal metastasis of ovarian tumors

2006 • 377 citations

Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma

1999 • 322 citations

CA125 in ovarian cancer: European Group on Tumor Markers guidelines for clinical use

2005 • 295 citations

92225921 Prospective evaluation of serum CA 125 levels for early detection of ovarian cancer

1993 • 271 citations

Elevated serum CA 125 levels prior to diagnosis of ovarian neoplasia: Relevance for early detection of ovarian cancer

1988 • 265 citations

Calculation of the Risk of Ovarian Cancer From Serial CA-125 Values for Preclinical Detection in Postmenopausal Women

2003 • 251 citations

Combining Several Screening Tests: Optimality of the Risk Score

2002 • 249 citations

Results From Four Rounds of Ovarian Cancer Screening in a Randomized Trial

2009 • 249 citations

The Preclinical Natural History of Serous Ovarian Cancer: Defining the Target for Early Detection

2009 • 237 citations

Characterization of the Oligosaccharides Associated with the Human Ovarian Tumor Marker CA125

2003 • 234 citations

Mesothelin Is Not Required for Normal Mouse Development or Reproduction

2000 • 228 citations

Menstrual and reproductive factors in relation to ovarian cancer risk

2001 • 188 citations

Combining CA 125 and SMR serum markers for diagnosis and early detection of ovarian carcinoma

2004 • 188 citations

CA125 in Ovarian Cancer

2007 • 185 citations

Contribution of Protein Fractionation to Depth of Analysis of the Serum and Plasma Proteomes

2007 • 165 citations

Early Detection of Ovarian Cancer: Promise and Reality

2002 • 142 citations

Bead-Based ELISA for Validation of Ovarian Cancer Early Detection Markers

2006 • 142 citations

Evaluation of the novel serum markers B7-H4, Spondin 2, and DcR3 for diagnosis and early detection of ovarian cancer

2007 • 102 citations

Peritoneal natural killer cells from epithelial ovarian cancer patients show an altered phenotype and bind to the tumour marker MUC16 (CA125)

2007 • 99 citations

Elevation of serum CA 125 prior to diagnosis of an epithelial ovarian carcinoma

1985 • 91 citations

Prospective Study of Serum CA-125 Levels as Markers of Ovarian Cancer

1993 • 88 citations

Multianalyte Profiling of Serum Antigens and Autoimmune and Infectious Disease Molecules to Identify Biomarkers Dysregulated in Epithelial Ovarian Cancer

2008 • 85 citations

Systematic Evaluation of Candidate Blood Markers for Detecting Ovarian Cancer

2008 • 84 citations

Prognostic value in predicting overall survival of two mucinous markers: CA 15-3 and CA 125 in breast cancer patients at first relapse of disease

1994 • 84 citations

A parametric empirical Bayes method for cancer screening using longitudinal observations of a biomarker

2003 • 72 citations

Statistical design and monitoring of the carotene and retinol efficacy trial (CARET)

1993 • 71 citations

Development and in vitro validation of anti-mesothelin biobodies that prevent CA125/Mesothelin-dependent cell attachment

2007 • 62 citations

Generating longitudinal screening algorithms using novel biomarkers for disease.

2002 • 61 citations

Elevated CA 125 in Breast Cancer – A Sign of Advanced Disease

2001 • 60 citations

Peritoneal lavage CEA/CA125 is a prognostic factor for gastric cancer patients

2007 • 52 citations

Serum CA 125 as a Prognostic Factor in Non-Hodgkin's Lymphoma

2003 • 50 citations

Method for generation of in vivo biotinylated recombinant antibodies by yeast mating

2006 • 47 citations

Tissue polypeptide antigen (TPA), hyaluronan and CA 125 as serum markers in malignant mesothelioma.

2003 • 43 citations

Early detection of ovarian cancer: new technologies in pursuit of a disease that is neither common nor rare.

2004 • 43 citations

Recent developments in the molecular, biochemical and functional characterization of GPI8 and the GPI-anchoring mechanism [Review]

2006 • 38 citations

Serum CA125: A Tumor Marker for Monitoring Response to Treatment and Follow-up in Patients with Non-Hodgkin's Lymphoma

2004 • 34 citations

Use of Yeast-Secreted In vivo Biotinylated Recombinant Antibodies (Biobodies) in Bead-Based ELISA

2008 • 28 citations

Increased CA 125 serum levels in patients with advanced acute leukemia with serosal involvement

2000 • 22 citations

Increased CA 125 serum levels in patients with advanced acute leukemia with serosal involvement

2000 • 21 citations

The changing incidence of cancer in adults in New South Wales

1988 • 20 citations

SERUM CA 125 LEVELS IN CHILDREN WITH NON-HODGKIN'S LYMPHOMA

1999 • 18 citations

Raised serum CA 125 level in leiomyoma and leiomyosarcoma of gastrointestinal origin

1993 • 8 citations

Elevated serum levels of macrophage colony-stimulating factor and OVX1, 11 months prior to the diagnosis of stage IC ovarian cancer

1996 • 3 citations

Deleted Work

1955 • 0 citations