Ectopic Expression of Cell Cycle Markers in Models of Induced Programmed Cell Death in Dopamine Neurons of the Rat Substantia Nigra Pars Compacta

The Rat Brain in Stereotaxic Coordinates

1982 • 53,055 citations

The rat brain in stereotaxic coordinates

1983 • 28,962 citations

Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation.

1992 • 9,540 citations

Neurogenesis in the dentate gyrus of the adult rat: age-related decrease of neuronal progenitor proliferation

1996 • 3,079 citations

Induction of apoptosis in fibroblasts by c-myc protein

1992 • 2,977 citations

NeuN, a neuronal specific nuclear protein in vertebratesxs

1992 • 2,268 citations

Stereology of arbitrary particles. A review of unbiased number and size estimators and the presentation of some new ones, in memory of William R. Thompson.

1986 • 1,669 citations

Stereology of arbitrary particles*

1986 • 1,404 citations

Altered gene expression in neurons during programmed cell death: identification of c-jun as necessary for neuronal apoptosis.

1994 • 820 citations

Role for c-myc in Activation-Induced Apoptotic Cell Death in T Cell Hybridomas

1992 • 705 citations

Ontogeny of monoamine neurons in the locus coeruleus, raphe nuclei and substantia nigra of the rat. I. Cell differentiation

1974 • 653 citations

Mutations of phosphorylation sites in lamin A that prevent nuclear lamina disassembly in mitosis

1990 • 642 citations

DNA Replication Precedes Neuronal Cell Death in Alzheimer's Disease

2001 • 609 citations

Use of bromodeoxyuridine-immunohistochemistry to examine the proliferation, migration and time of origin of cells in the central nervous system

1988 • 604 citations

Analysis of cell cycle-related gene expression in postmitotic neurons: Selective induction of cyclin D1 during programmed cell death

1994 • 576 citations

Premature p34 ^cdc2 Activation Required for Apoptosis

1994 • 568 citations

Ectopic Cell Cycle Proteins Predict the Sites of Neuronal Cell Death in Alzheimer’s Disease Brain

1998 • 537 citations

NeuN: a useful neuronal marker for diagnostic histopathology.

1996 • 507 citations

Aberrant Expression of Mitotic Cdc2/Cyclin B1 Kinase in Degenerating Neurons of Alzheimer’s Disease Brain

1997 • 444 citations

Ontogeny of monoamine neurons in the locus coeruleus, raphe nuclei and substantia nigra of the rat

1975 • 411 citations

Mitotic mechanisms in Alzheimer's disease?

1996 • 384 citations

Cyclin D1 is an essential mediator of apoptotic neuronal cell death.

1996 • 383 citations

Apoptosis and Its Relation to the Cell Cycle in the Developing Cerebral Cortex

1997 • 370 citations

Cascade Induction of c-fos, c-myc, and Heat Shock 70K Transcripts during Regression of the Rat Ventral Prostate Gland

1988 • 355 citations

Apoptotic-like changes in Lewy-body-associated disorders and normal aging in substantia nigral neurons.

1997 • 286 citations

Control of the cell cycle and apoptosis

1999 • 285 citations

G1/S Cell Cycle Blockers and Inhibitors of Cyclin-Dependent Kinases Suppress Camptothecin-Induced Neuronal Apoptosis

1997 • 275 citations

Cyclin Dependent Kinase Inhibitors and Dominant Negative Cyclin Dependent Kinase 4 and 6 Promote Survival of NGF-Deprived Sympathetic Neurons

1997 • 270 citations

Cyclin-dependent Kinases Participate in Death of Neurons Evoked by DNA-damaging Agents

1998 • 264 citations

Inhibitors of Cyclin-dependent Kinases Promote Survival of Post-mitotic Neuronally Differentiated PC12 Cells and Sympathetic Neurons

1996 • 252 citations

Hormone-regulated apoptosis results from reentry of differentiated prostate cells onto a defective cell cycle.

1992 • 245 citations

Involvement of Cell Cycle Elements, Cyclin-dependent Kinases, pRb, and E2F·DP, in B-amyloid-induced Neuronal Death

1999 • 242 citations

The induction of multiple cell cycle events precedes target-related neuronal death

1995 • 214 citations

Disrupted cerebellar cortical development and progressive degeneration of Purkinje cells in SV40 T antigen transgenic mice

1992 • 211 citations

Chapter 13 Neuron Death in Vertebrate Development: In Vivo Methods

1995 • 194 citations

Mitotic activation: a convergent mechanism for a cohort of neurodegenerative diseases

2000 • 189 citations

Migration of dopaminergic neurons in the embryonic mesencephalon of mice

1995 • 162 citations

The time course of developmental cell death in phenotypically defined dopaminergic neurons of the substantia nigra

1997 • 158 citations

Involvement of Retinoblastoma Family Members and E2F/DP Complexes in the Death of Neurons Evoked by DNA Damage

2000 • 151 citations

Bromodeoxyuridine: a diagnostic tool in biology and medicine, Part I: Historical perspectives, histochemical methods and cell kinetics

1995 • 148 citations

Apoptosis in substantia nigra following developmental striatal excitotoxic injury.

1994 • 129 citations

Naturally Occurring Cell Death during Postnatal Development of the Substantia Nigra Pars Compacta of Rat

1993 • 124 citations

Bromodeoxyuridine: a diagnostic tool in biology and medicine, Part I: Historical perspectives, histochemical methods and cell kinetics

1995 • 119 citations

Activation of Caspase‐3 in Developmental Models of Programmed Cell Death in Neurons of the Substantia Nigra

1999 • 114 citations

Early Developmental Destruction of Terminals in the Striatal Target Induces Apoptosis in Dopamine Neurons of the Substantia Nigra

1997 • 107 citations

Dopaminergic cells align along radial glia in the developing mesencephalon of the rat

1990 • 103 citations

Proliferative inhibition by dominant-negative Ras rescues naive and neuronally differentiated PC12 cells from apoptotic death.

1994 • 103 citations

Isthmic origin of neurons of the rat substantia nigra

1983 • 101 citations

Downregulation of CDC2 upon terminal differentiation of neurons.

1991 • 86 citations

Apoptosis and cell division

2000 • 75 citations

Stereotaxic electrode placement in the neonatal rat

1979 • 64 citations

Medial forebrain bundle axotomy during development induces apoptosis in dopamine neurons of the substantia nigra and activation of caspases in their degenerating axons

2002 • 50 citations

Oncogene expression in retinal horizontal cells of transgenic mice results in a cascade of neurodegeneration

1993 • 45 citations

Distinct Nuclear and Cytoplasmic Localization of Caspase Cleavage Products in Two Models of Induced Apoptotic Death in Dopamine Neurons of the Substantia Nigra

2002 • 43 citations

Expression of cyclin‐dependent kinase 5 and its activator p35 in models of induced apoptotic death in neurons of the substantia nigra in vivo

2001 • 43 citations

The expression of mRNAs for the proteasome complex is developmentally regulated in the rat mesencephalon

2001 • 37 citations

Apoptotic cell death in neuronal differentiation of P19 EC cells: Cell death follows reentry into S phase

1997 • 29 citations

Three to Four-Year-Old Nonpassaged EGF-Responsive Neural Progenitor Cells: Proliferation, Apoptosis, and DNA Repair

2000 • 28 citations