Enhanced cellular uptake of a triplex-forming oligonucleotide by nanoparticle formation in the presence of polypropylenimine dendrimers

A novel non-viral vector for DNA delivery based on low molecular weight, branched polyethylenimine: effect of molecular weight on transfection efficiency and cytotoxicity.

1999 • 1,190 citations

Polyamidoamine cascade polymers mediate efficient transfection of cells in culture

1993 • 1,186 citations

Size matters: Molecular weight affects the efficiency of poly(ethylenimine) as a gene delivery vehicle

1999 • 801 citations

The influence of polymer structure on the interactions of cationic polymers with DNA and morphology of the resulting complexes

1997 • 798 citations

Site-Specific Oligonucleotide Binding Represses Transcription of the Human c- myc Gene in Vitro

1988 • 707 citations

Design and gene delivery activity of modified polyethylenimines

2001 • 652 citations

Preliminary biological evaluation of polyamidoamine (PAMAM) StarburstTM dendrimers

1996 • 572 citations

Regulation of in vitro gene expression using antisense oligonucleotides or antisense expression plasmids transfected using starburst PAMAM dendrimers

1996 • 453 citations

Dendrimers and Dendrons: Concepts, Syntheses, Applications

2001 • 383 citations

DNA Nanoparticles and Development of DNA Delivery Vehicles for Gene Therapy

2002 • 356 citations

The lower-generation polypropylenimine dendrimers are effective gene-transfer agents.

2002 • 310 citations

Novel Antisense and Peptide Nucleic Acid Strategies for Controlling Gene Expression

2002 • 243 citations

Antisense Oligonucleotides: Promise and Reality

2001 • 240 citations

Towards synthetic viruses

2001 • 217 citations

Nucleic Acid Therapeutics: State of the Art and Future Prospects

1998 • 215 citations

DNA Condensation by Polyamines: A Laser Light Scattering Study of Structural Effects

2001 • 205 citations

Nucleic Acid Therapeutics: State of the Art and Future Prospects

1998 • 190 citations

Dendrimer-based Macromolecular MRI Contrast Agents: Characteristics and Application

2003 • 187 citations

Nonviral Gene Delivery to the Rat Kidney with Polyethylenimine

1997 • 186 citations

Enhanced delivery of antisense oligonucleotides with fluorophore-conjugated PAMAM dendrimers

2000 • 181 citations

Biological Properties of Poly-l-lysine-DNA Complexes Generated by Cooperative Binding of the Polycation

2001 • 158 citations

Major limitations in the use of cationic liposomes for DNA delivery

1998 • 151 citations

DNA transfection and transfected cell viability using amphipathic asymmetric dendrimers

2000 • 148 citations

The potential for gene repair via triple helix formation

2003 • 141 citations

Armed therapeutic viruses: Strategies and challenges to arming oncolytic viruses with therapeutic genes

2002 • 134 citations

Phase Behavior of Cationic Amphiphiles and Their Mixtures with Helper Lipid Influences Lipoplex Shape, DNA Translocation, and Transfection Efficiency

2002 • 128 citations

Self-Assembled Ternary Complex of Cationic Dendrimer, Cucurbituril, and DNA: Noncovalent Strategy in Developing a Gene Delivery Carrier

2002 • 120 citations

Electron microscopy and biochemical properties of polyamine-compacted DNA

1987 • 118 citations

Structural polymorphism of DNA-dendrimer complexes

2003 • 95 citations

In vitro myotoxicity of selected cationic macromolecules used in non-viral gene delivery.

1998 • 93 citations

DNA-Directed Synthesis of Generation 7 and 5 PAMAM Dendrimer Nanoclusters

2004 • 91 citations

Innovations in Oligonucleotide Drug Delivery

2003 • 83 citations

Polyamine structural effects on the induction and stabilization of liquid crystalline DNA: potential applications to DNA packaging, gene therapy and polyamine therapeutics

2002 • 78 citations

Formation of DNA nanoparticles in the presence of novel polyamine analogues: a laser light scattering and atomic force microscopic study

2004 • 74 citations

Suppression of c-myconcogene expression by a polyamine-complexed triplex forming oligonucleotide in MCF-7 breast cancer cells

1995 • 60 citations

Dendrimer-based Macromolecular MRI Contrast Agents: Characteristics and Application

2003 • 54 citations

Dynamic micro-magnetic resonance imaging of liver micrometastasis in mice with a novel liver macromolecular magnetic resonance contrast agent DAB-Am64-(1B4M-Gd)(64).

2001 • 50 citations

Estradiol control of ornithine decarboxylase mRNA, enzyme activity, and polyamine levels in MCF-7 breast cancer cells: therapeutic implications

1994 • 43 citations

Phosphodiester and phosphorothioate oligonucleotide condensation and preparation of antisense nanoparticles

2001 • 43 citations

Viruses in therapy—royal road or dead end?

2003 • 39 citations

Model of Inversion of DNA Charge by a Positive Polymer: Fractionalization of the Polymer Charge

2002 • 36 citations

Development of plasmid and oligonucleotide nanometric particles

2002 • 30 citations

Facilitation of the Cellular Uptake of a Triplex-Forming Oligonucleotide by Novel Polyamine Analogues: Structure−Activity Relationships

1999 • 21 citations

Oligonucleotide-mediated gene repair at DNA level: the potential applications for gene therapy

2002 • 18 citations

The potential for gene repair via triple helix formation

2003 • 13 citations

Deleted Work

1955 • 0 citations

Cited By (0)

Loading...