THE ISOPROSTANES: THEIR QUANTIFICATION AS AN INDEX OF OXIDANT STRESS STATUS IN VIVO^†

Oxidative Stress Hypothesis in Alzheimer's Disease

1997 • 2,355 citations

A series of prostaglandin F2-like compounds are produced in vivo in humans by a non-cyclooxygenase, free radical-catalyzed mechanism.

1990 • 1,896 citations

Free-radical chemistry of cigarette smoke and its toxicological implications.

1985 • 1,351 citations

Increase in Circulating Products of Lipid Peroxidation (F₂-Isoprostanes) in Smokers — Smoking as a Cause of Oxidative Damage

1995 • 1,343 citations

Non-cyclooxygenase-derived prostanoids (F2-isoprostanes) are formed in situ on phospholipids.

1992 • 742 citations

Modulation of Oxidant Stress In Vivo in Chronic Cigarette Smokers

1996 • 621 citations

The isoprostanes: Unique bioactive products of lipid peroxidation

1997 • 561 citations

Noncyclooxygenase oxidative formation of a series of novel prostaglandins: Analytical ramifications for measurement of eicosanoids

1990 • 480 citations

Mass spectrometric quantification of F2-isoprostanes in biological fluids and tissues as measure of oxidant stress

1999 • 414 citations

The measurement of free radical reactions in humans

1987 • 325 citations

Formation of novel non-cyclooxygenase-derived prostanoids (F2-isoprostanes) in carbon tetrachloride hepatotoxicity. An animal model of lipid peroxidation.

1992 • 319 citations

Increased CSF F ₂ -isoprostane concentration in probable AD

1999 • 250 citations

Cerebrospinal fluid F₂‐isoprostane levels are increased in Alzheimer's disease

1998 • 241 citations

Free-Radical Chemistry of Cigarette Smoke and Its Toxicological Implications

1985 • 217 citations

A nomenclature system for the isoprostanes

1997 • 196 citations

Pathogenesis of diquat-induced liver necrosis in selenium-deficient rats: Assessment of the roles of lipid peroxidation and selenoprotein P

1995 • 168 citations

Evidence of free radical–mediated injury (isoprostane overproduction) in scleroderma

1996 • 162 citations

A radical proposal for the pathogenesis of scleroderma

1993 • 152 citations

THE ISOPROSTANES: UNIQUE PROSTAGLANDIN-LIKE PRODUCTS OF FREE-RADICAL-INITIATED LIPID PEROXIDATION*

1999 • 121 citations

The Magnitude of Brain Lipid Peroxidation Correlates with the Extent of Degeneration but Not with Density of Neuritic Plaques or Neurofibrillary Tangles or with APOE Genotype in Alzheimer's Disease Patients

1999 • 118 citations

Detection and Localization of Lipid Peroxidation in Selenium- and Vitamin E—Deficient Rats Using F2-Isoprostanes

1994 • 107 citations

Marked overproduction of non-cyclooxygenase derived prostanoids (F2-isoprostanes) in the hepatorenal syndrome.

1993 • 96 citations

Plasma levels of 8-epiPGF2α, an in vivo marker of oxidative stress, are not affected by aging or Alzheimer’s disease

1999 • 88 citations

ISOPROSTANES—RROSTAGLANDIN-LIKE COMPOUNDS FORMED IN VIVO INDEPENDENTLY OF CYCLOOXYGENASE

1996 • 74 citations

Free radicals of acetaminophen: their subsequent reactions and toxicological significance.

1986 • 41 citations

Isoprostanes as Markers of Lipid Peroxidation in Atherosclerosis

1999 • 29 citations

Formation of 8-iso-prostaglandin F2 alpha by human platelets.

1995 • 14 citations