Immunological control of murine gammaherpesvirus infection is independent of perforin.

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

1994 • 1,772 citations

Intracellular Inactivation of the Hepatitis B Virus by Cytotoxic T Lymphocytes

1996 • 1,085 citations

Progressive loss of CD8+ T cell-mediated control of a gamma-herpesvirus in the absence of CD4+ T cells.

1996 • 515 citations

Immune function in mice lacking the perforin gene.

1994 • 474 citations

In vivo effector function of influenza virus-specific cytotoxic T lymphocyte clones is highly specific.

1984 • 439 citations

Transgenic mice lacking class I major histocompatibility complex-restricted T cells have delayed viral clearance and increased mortality after influenza virus challenge.

1992 • 381 citations

Clearance of influenza virus respiratory infection in mice lacking class I major histocompatibility complex-restricted CD8+ T cells.

1991 • 372 citations

Murine gammaherpesvirus 68 establishes a latent infection in mouse B lymphocytes in vivo

1992 • 351 citations

Protection against lethal Sendai virus infection by in vivo priming of virus-specific cytotoxic T lymphocytes with a free synthetic peptide.

1991 • 334 citations

Virological and pathological features of mice infected with murine gammaherpesvirus 68

1992 • 316 citations

The roles of perforin‐ and Fas‐dependent cytotoxicity in protection against cytopathic and noncytopathic viruses

1995 • 286 citations

Influenza nucleoprotein-specific cytotoxic T-cell clones are protective in vivo.

1986 • 261 citations

Upregulation of class I major histocompatibility complex antigens by interferon gamma is necessary for T-cell-mediated elimination of recombinant adenovirus-infected hepatocytes in vivo.

1995 • 258 citations

Delayed clearance of Sendai virus in mice lacking class I MHC-restricted CD8+ T cells.

1992 • 237 citations

CD8+ T cell-mediated protection against an intracellular bacterium by perforin-dependent cytotoxicity

1994 • 229 citations

A null mutation in the perforin gene impairs cytolytic T lymphocyte- and natural killer cell-mediated cytotoxicity.

1994 • 224 citations

Murine herpesvirus 68 is genetically related to the gammaherpesviruses Epstein-Barr virus and herpesvirus saimiri

1990 • 222 citations

Pathogenesis of murine gammaherpesvirus infection in mice deficient in CD4 and CD8 T cells

1993 • 192 citations

Lymphoproliferative disease in mice infected with murine gammaherpesvirus 68.

1994 • 191 citations

Cloning and molecular characterization of the murine herpesvirus 68 genome

1990 • 170 citations

Mouse hepatitis virus is cleared from the central nervous systems of mice lacking perforin-mediated cytolysis

1997 • 145 citations

Concurrent production of interleukin-2, interleukin-10, and gamma interferon in the regional lymph nodes of mice with influenza pneumonia

1994 • 134 citations

Murine gammaherpesvirus-induced splenomegaly: a critical role for CD4 T cells

1996 • 127 citations

Evidence for CD8+ T-cell immunity to murine rotavirus in the absence of perforin, fas, and gamma interferon

1997 • 95 citations

Immune CD4+ T cells promote the clearance of influenza virus from major histocompatibility complex class II -/- respiratory epithelium

1996 • 89 citations

In vitro analysis of the epstein‐barr virus: Host balance in long‐term renal allograft recipients

1985 • 86 citations

The role of the Fas lytic pathway in a perforin-less CTL hybridoma.

1994 • 86 citations

Cytokine production in the immune response to murine gammaherpesvirus 68

1996 • 75 citations

Studies on long‐term T‐cell‐mediated immunity to epstein‐barr virus in immunosuppressed renal allograft recipients

1981 • 67 citations

Interactions of Murine Gammaherpesvirus 68 with B and T Cell Lines

1993 • 60 citations

Activation status of the CD4-8- gamma delta-T cells recovered from mice with influenza pneumonia.

1991 • 48 citations

Clearance of Sendai virus by CD8⁺ T cells requires direct targeting to virus‐infected epithelium

1995 • 45 citations

Immunological features of murine gammaherpesvirus infection

1996 • 24 citations