Biochemical differences in the mechanism of macrophage lysosomal exocytosis initiated by zymosan particles and weak bases

Fluorescence probe measurement of the intralysosomal pH in living cells and the perturbation of pH by various agents.

1978 • 2,146 citations

Lysosomotropic agents

1974 • 1,887 citations

Effect of weak bases on the intralysosomal pH in mouse peritoneal macrophages.

1981 • 736 citations

Evidence for receptor-mediated binding of glycoproteins, glycoconjugates, and lysosomal glycosidases by alveolar macrophages.

1978 • 593 citations

Receptor-mediated pinocytosis of mannose glycoconjugates by macrophages: Characterization and evidence for receptor recycling

1980 • 574 citations

Transglutaminase is essential in receptor-mediated endocytosis of α2-macroglobulin and polypeptide hormones

1980 • 535 citations

Cytoplasmic vacuolation of mouse peritoneal macrophages and the uptake into lysosomes of weakly basic substances.

1981 • 424 citations

The permeability properties of the lysosomal membrane

1977 • 198 citations

Immune Complexes induce Selective Release of Lysosomal Hydrolases from Macrophages

1974 • 173 citations

Effects of activated complement components on enzyme secretion by macrophages.

1976 • 162 citations

AUTOPHAGIC VACUOLES PRODUCED IN VITRO

1968 • 159 citations

2-Deoxyglucose selectively inhibits Fc and complement receptor-mediated phagocytosis in mouse peritoneal macrophages. I. Description of the inhibitory effect.

1976 • 158 citations

CHANGES IN CELLULAR ENZYME LEVELS AND EXTRACELLULAR RELEASE OF LYSOSOMAL ACID HYDROLASES IN MACROPHAGES EXPOSED TO GROUP A STREPTOCOCCAL CELL WALL SUBSTANCE

1974 • 155 citations

Evidence that proteases are involved in superoxide production by human polymorphonuclear leukocytes and monocytes.

1980 • 146 citations

Evidence for participation of transglutaminase in receptor-mediated endocytosis.

1980 • 130 citations

Complement activation by the alternative pathway and macrophage enzyme secretion in the pathogenesis of chronic inflammation.

1977 • 130 citations

2-Deoxyglucose selectively inhibits Fc and complement receptor-mediated phagocytosis in mouse peritoneal macrophages II. Dissociation of the inhibitory effects of 2-deoxyglucose on phagocytosis and ATP generation.

1976 • 123 citations

MECHANISMS OF IMMUNOLOGIC INJURY OF RAT PERITONEAL MAST CELLS

1966 • 119 citations

Opsonin-Independent Phagocytosis of Activators of the Alternative Complement Pathway by Human Monocytes

1978 • 114 citations

Mononuclear Phagocytes

1985 • 72 citations

Macrophage responses to mouldy hay dust, Micropolyspora faeni and zymosan, activators of complement by the alternative pathway.

1977 • 68 citations

The Role of an Activatable Esterase in Immune-Dependent Phagocytosis by Human Neutrophils

1977 • 64 citations

Primary amines induce selective release of lysosomal enzymes from mouse macrophages

1980 • 56 citations

Studies on the possible involvement of complement component C3 in the initiation of acid hydrolase secretion by macrophages. I. Correlation between enzyme-releasing and complement-activating capacities of several secretagogues.

1981 • 29 citations

Factor B of the Alternative Complement Pathway on Human Lymphocytes

1976 • 25 citations

Induction of selective acid hydrolase release from mouse macrophages during exposure to chloroquine and quinine

1981 • 24 citations

The effect of weak bases on lysosomal enzyme secretion by mononuclear phagocytes

1982 • 23 citations

Inhibition of cell spreading by lysosomotropic amines

1979 • 21 citations

Evidence for a mechanism for the initiation of acid hydrolase secretion by macrophages that is functionally independent of alternative pathway complement activation

1982 • 16 citations

Organophosphorus inhibition of lysosomal enzyme secretion from polymorphonuclear leucocytes. Evidence of a lack of a requirement for esterase activation.

1978 • 14 citations