Microtubule dynamics at the G2/M transition: abrupt breakdown of cytoplasmic microtubules at nuclear envelope breakdown and implications for spindle morphogenesis.

Beyond self-assembly: From microtubules to morphogenesis

1986 • 1,334 citations

Human cyclins A and B1 are differentially located in the cell and undergo cell cycle-dependent nuclear transport.

1991 • 858 citations

Cell Motility by Labile Association of Molecules

1967 • 767 citations

Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence.

1989 • 603 citations

Identification of katanin, an ATPase that severs and disassembles stable microtubules

1993 • 490 citations

Tubulin dynamics in cultured mammalian cells.

1984 • 489 citations

Regulation of microtubule dynamics by cdc2 protein kinase in cell-free extracts of Xenopus eggs

1990 • 446 citations

Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts

1990 • 444 citations

Control of microtubule dynamics and length by cyclin A- and cyclin B-dependent kinases in Xenopus egg extracts.

1992 • 419 citations

Polewards chromosome movement driven by microtubule depolymerization in vitro

1988 • 409 citations

Directional instability of kinetochore motility during chromosome congression and segregation in mitotic newt lung cells: a push-pull mechanism

1993 • 389 citations

Chromosomes move poleward in anaphase along stationary microtubules that coordinately disassemble from their kinetochore ends.

1987 • 314 citations

Cyclin B2 undergoes cell cycle-dependent nuclear translocation and, when expressed as a non-destructible mutant, causes mitotic arrest in HeLa cells

1992 • 298 citations

Kinetochore microtubule dynamics and the metaphase-anaphase transition.

1995 • 292 citations

Cyclin B interaction with microtubule-associated protein 4 (MAP4) targets p34cdc2 kinase to microtubules and is a potential regulator of M-phase microtubule dynamics.

1995 • 279 citations

Microtubule treadmills—possible molecular machinery

1981 • 279 citations

Microtubule Severing by Elongation Factor 1α

1994 • 252 citations

Microtubule Dynamics: Mechanism, Regulation, and Function

1991 • 228 citations

Antibodies to the kinesin motor domain and CENP-E inhibit microtubule depolymerization-dependent motion of chromosomes in vitro.

1995 • 222 citations

Microtubule depolymerization promotes particle and chromosome movement in vitro.

1991 • 215 citations

Severing of stable microtubules by a mitotically activated protein in xenopus egg extracts

1991 • 196 citations

Microtubule-nucleating activity of centrosomes in Chinese hamster ovary cells is independent of the centriole cycle but coupled to the mitotic cycle.

1981 • 191 citations

Kinetochore motility after severing between sister centromeres using laser microsurgery: Evidence that kinetochore directional instability and position is regulated by tension

1995 • 128 citations

Role of the centrosome in organizing the interphase microtubule array: properties of cytoplasts containing or lacking centrosomes.

1984 • 121 citations

Microtubule dynamics in vivo: a test of mechanisms of turnover.

1987 • 120 citations

The force-producing mechanism for centrosome separation during spindle formation in vertebrates is intrinsic to each aster

1993 • 112 citations

Microtubules are stabilized in confluent epithelial cells but not in fibroblasts.

1990 • 103 citations

The impact of chromosomes and centrosomes on spindle assembly as observed in living cells.

1995 • 99 citations

Stability of microtubule attachment to metaphase kinetochores in PTK1 cells

1990 • 86 citations

Microtubule assembly and kinetochore directional instability in vertebrate monopolar spindles: Implications for the mechanism of chromosome congression

1994 • 80 citations

Microtubule dynamics in fish melanophores.

1994 • 76 citations

Quantitative determination of the proportion of microtubule polymer present during the mitosis-interphase transition

1994 • 76 citations

A new role for motor proteins as couplers to depolymerizing microtubules.

1995 • 67 citations

The total length of spindle microtubules depends on the number of chromosomes present.

1985 • 60 citations

A novel homo-oligomeric protein responsible for an MPF-dependent microtubule-severing activity.

1992 • 51 citations

Variations in the distribution and migration of centriole duplexes in mitotic ptk2 cells studied by immunofluorescence microscopy

1980 • 50 citations

Distribution of microtubules during centriole separation in rat kangaroo (Potorous) cells.

1976 • 44 citations

Morphogenesis of the Mitotic and Meiotic Spindle: Conclusions Obtained From one System are not Necessarily Applicable to the Other

1993 • 41 citations

The dynamics of reconstitution of microtubules around the cell center after cooling.

1983 • 33 citations

The three‐dimensional architecture of the mitotic spindle, analyzed by confocal fluorescence and electron microscopy

1991 • 22 citations

Pole-to-chromosome movements induced at metaphase: Sites of microtubule disassembly

1991 • 17 citations