Astrocyte-Derived Monocyte-Chemoattractant Protein-1 Directs the Transmigration of Leukocytes Across a Model of the Human Blood-Brain Barrier

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The Glomerular Permeability Determined by Dextran Clearance Using Sephadex Gel Filtration

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VCAM-1 on activated endothelium interacts with the leukocyte integrin VLA-4 at a site distinct from the VLA-4/Fibronectin binding site

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Prevention of experimental autoimmune encephalomyelitis by antibodies against α4βl integrin

1992 • 1,711 citations

Monocyte chemoattractant protein 1 acts as a T-lymphocyte chemoattractant.

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Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions.

1991 • 879 citations

Tumor necrosis factor identified in multiple sclerosis brain.

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Cytokine production by human fetal microglia and astrocytes. Differential induction by lipopolysaccharide and IL-1 beta.

1993 • 789 citations

The adhesion molecule and cytokine profile of multiple sclerosis lesions

1995 • 761 citations

Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions.

1991 • 735 citations

Enhanced production of monocyte chemoattractant protein-1 in rheumatoid arthritis.

1992 • 667 citations

Human monocyte chemoattractant protein-1 (MCP-1)

1990 • 666 citations

Tumor necrosis factor-alpha production by astrocytes. Induction by lipopolysaccharide, IFN-gamma, and IL-1 beta.

1990 • 604 citations

Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia

1998 • 568 citations

The activation antigen CD69

1994 • 516 citations

Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-1/JE.

1990 • 500 citations

Astrocyte expression of mRNA encoding cytokines IP‐10 and JE/MCP‐1 in experimental autoimmune encephalomyelitis

1993 • 496 citations

Transforming growth factor beta: the good, the bad, and the ugly.

1994 • 491 citations

Monocyte chemoattractant protein 1: a potential regulator of monocyte recruitment in inflammatory disease

1996 • 390 citations

Controlled recruitment of monocytes and macrophages to specific organs through transgenic expression of monocyte chemoattractant protein-1.

1995 • 389 citations

MCP-1, MCP-2 and MCP-3 expression in multiple sclerosis lesions: an immunohistochemical and in situ hybridization study

1998 • 371 citations

Unique monocyte subset in patients with AIDS dementia

1997 • 371 citations

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1990 • 369 citations

Mechanisms for the transendothelial migration of HIV-1-infected monocytes into brain.

1996 • 321 citations

A model for monocyte migration through the blood-brain barrier during HIV-1 encephalitis.

1997 • 316 citations

MIP-1α and MCP-1 differentially regulate acute and relapsing autoimmune encephalomyelitis as well as Th1/Th2 lymphoctye differentiation

1997 • 312 citations

Human immunodeficiency virus type 1 infection alters chemokine beta peptide expression in human monocytes: implications for recruitment of leukocytes into brain and lymph nodes.

1996 • 288 citations

Induction of various blood-brain barrier properties in non-neural endothelial cells by close apposition to co-cultured astrocytes

1997 • 266 citations

Localization of monocyte chemoattractant peptide-1 expression in the central nervous system in experimental autoimmune encephalomyelitis and trauma in the rat.

1996 • 244 citations

Expression of CSF-1, c-fms, and MCP-1 in the central nervous system of rats with experimental allergic encephalomyelitis.

1993 • 218 citations

Neutrophil and monocyte adherence to and migration across monolayers of cytokine-activated endothelial cells: the contribution of CD18, ELAM-1, and VLA-4

1991 • 175 citations

Studies on the mechanisms by which transforming growth factor-beta (TGF-beta) protects against allergic encephalomyelitis. Antagonism between TGF-beta and tumor necrosis factor.

1993 • 170 citations

Expression of immunologically relevant endothelial cell activation antigens on isolated central neurvous system microvessels from patients with multiple sclerosis

1994 • 170 citations

Cytokine induction of MIP-1 alpha and MIP-1 beta in human fetal microglia.

1998 • 166 citations

Astroglial overproduction of TGF-β1 enhances inflammatory central nervous system disease in transgenic mice

1997 • 152 citations

Chemokines

1997 • 145 citations

A soluble gradient of endogenous monocyte chemoattractant protein-1 promotes the transendothelial migration of monocytes in vitro.

1995 • 144 citations

Cytokine Induction of MIP-1α and MIP-1β in Human Fetal Microglia

1998 • 143 citations

Human fetal astrocytes induce the expression of blood-brain barrier specific proteins by autologous endothelial cells

1993 • 130 citations

Tumor necrosis factor α and transforming growth factor β upregulate astrocyte expression of monocyte chemoattractant protein-1

1995 • 129 citations

Transendothelial migration and trafficking of leukocytes in LFA-1-deficient mice

1998 • 125 citations

Induction of Monocyte Chemoattractant Protein-1 Synthesis in Human Monocytes During Transendothelial Migration In Vitro

1995 • 104 citations

Monocyte adhesion to endothelium in simian immunodeficiency virus-induced AIDS encephalitis is mediated by vascular cell adhesion molecule-1/alpha 4 beta 1 integrin interactions.

1994 • 101 citations

Immunology of multiple sclerosis.

1994 • 100 citations

Traffic of Hematogenous Cells Through the Central Nervous System

1995 • 98 citations

Platelet-derived Growth Factor Induction of the Immediate-early gene Is Mediated by NF-κB and a 90-kDa Phosphoprotein Coactivator

1996 • 88 citations

The blood‐brain barrier: Cellular basis

1993 • 77 citations

Long-term treatment of chronic relapsing experimental allergic encephalomyelitis by transforming growth factor-β2

1993 • 74 citations

Regulation and expression of chemokines: potential role in glomerulonephritis

1996 • 63 citations

Astrocyte expression of monocyte chemoattractant protein-1 is differentially regulated by transforming growth factor beta

1998 • 46 citations

Suppression of experimental autoimmune encephalomyelitis with a TNF binding protein (TNFbp) correlates with down-regulation of VCAM-1/VLA-4

1998 • 37 citations

TGF-Beta Downmodulates Cytokine-Induced Monocyte Chemoattractant Protein (MCP)-1 Expression in Human Endothelial Cells. A Putative Role for TGF-Beta in the Modulation of TNF Receptor Expression

1999 • 35 citations

An endothelial cell adhesion protein for monocytes recognized by monoclonal antibody IG9. Expression in vivo in inflamed human vessels and atherosclerotic human and Watanabe rabbit vessels.

1994 • 32 citations

Astrocytic adhesion molecules are increased in HIV‐1‐associated cognitive/motor complex

1997 • 31 citations

Transendothelial migration of lymphocytes from HIV-1-infected donors: a mechanism for extravascular dissemination of HIV-1.

1997 • 26 citations

Human fetal central nervous system organotypic cultures

1991 • 24 citations

Neutrophil and monocyte adherence to and migration across monolayers of cytokine-activated endothelial cells: the contribution of CD18, ELAM-1, and VLA-4

1991 • 24 citations

Astrocytic adhesion molecules are increased in HIV-1-associated cognitive/motor complex

1997 • 4 citations