Neoadjuvant Chemotherapy With High-Dose Ifosfamide, High-Dose Methotrexate, Cisplatin, and Doxorubicin for Patients With Localized Osteosarcoma of the Extremity: A Joint Study by the Italian and Scandinavian Sarcoma Groups

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1979 • 2,308 citations

The Effect of Adjuvant Chemotherapy on Relapse-Free Survival in Patients with Osteosarcoma of the Extremity

1986 • 1,164 citations

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Adjuvant chemotherapy for osteosarcoma: a randomized prospective trial.

1987 • 528 citations

Adjuvant Methotrexate and Citrovorum-Factor Treatment of Osteogenic Sarcoma

1974 • 484 citations

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1988 • 461 citations

Long-Term Outcome for Patients With Nonmetastatic Osteosarcoma of the Extremity Treated at the Istituto Ortopedico Rizzoli According to the Istituto Ortopedico Rizzoli/Osteosarcoma-2 Protocol: An Updated Report

2000 • 418 citations

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Current concepts review. The surgical staging of musculoskeletal sarcoma.

1980 • 328 citations

Amputation and Adriamycin in Primary Osteosarcoma

1974 • 319 citations

A comparison of two short intensive adjuvant chemotherapy regimens in operable osteosarcoma of limbs in children and young adults: the first study of the European Osteosarcoma Intergroup.

1992 • 315 citations

Primary chemotherapy and delayed surgery for nonmetastatic osteosarcoma of the extremities. Results in 164 patients preoperatively treated with high doses of methotrexate followed by cisplatin and doxorubicin

1993 • 305 citations

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Recent advances in the chemotherapy of metastatic osteogenic sarcoma

1972 • 276 citations

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1985 • 274 citations

High-dose ifosfamide in bone and soft tissue sarcomas: results of phase II and pilot studies--dose-response and schedule dependence.

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Treatment of osteosarcoma of the extremities with the T-10 protocol, with emphasis on the effects of preoperative chemotherapy with single-agent high-dose methotrexate: a Scandinavian Sarcoma Group study.

1991 • 227 citations

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1982 • 191 citations

Neoadjuvant chemotherapy for osteosarcoma of the extremity

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Scandinavian Sarcoma Group Osteosarcoma Study SSG VIII

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High-Dose Chemotherapy in the Treatment of Relapsed Osteosarcoma: An Italian Sarcoma Group Study

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1978 • 107 citations

High Dose Ifosfamide in Combination with High Dose Methotrexate, Adriamycin and Cisplatin in the Neoadjuvant Treatment of Extremity Osteosarcoma: Preliminary Results of an Italian Sarcoma Group/Scandinavian Sarcoma Group Pilot Study

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Neoadjuvant Chemotherapy for Extremity Osteosarcoma: Preliminary Results of the Rizzoli's 4th Study

1998 • 89 citations

Phase II trial of ifosfamide in children with malignant solid tumors.

1987 • 74 citations

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Prospective evaluation of high-dose ifosfamide-related nephrotoxicity in young adult patients with recurrent osteosarcoma previously treated with cisplatin, methotrexate and standard-dose ifosfamide

1999 • 11 citations